Showing entry for Hepatocyte nuclear factor 4-alpha


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT008769
Protein NameHepatocyte nuclear factor 4-alpha
Uniport IdP22449
GeneHnf4a
Gene Id25735
DomainHormone_recep; zf-C4
Pfam PF00104   PF00105  
OrganismRattus norvegicus (Rat)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006637 acyl-CoA metabolic process
Biological Process GO:0007568 aging
Biological Process GO:0048856 anatomical structure development
Biological Process GO:0007596 blood coagulation
Biological Process GO:0045216 cell-cell junction organization
Biological Process GO:0030154 cell differentiation
Biological Process GO:0071456 cellular response to hypoxia
Biological Process GO:0042632 cholesterol homeostasis
Biological Process GO:0007164 establishment of tissue polarity
Biological Process GO:0042593 glucose homeostasis
Biological Process GO:0070365 hepatocyte differentiation
Biological Process GO:0055088 lipid homeostasis
Biological Process GO:0006629 lipid metabolic process
Biological Process GO:1902569 negative regulation of activation of Janus kinase activity
Biological Process GO:0030308 negative regulation of cell growth
Biological Process GO:0030336 negative regulation of cell migration
Biological Process GO:0008285 negative regulation of cell population proliferation
Biological Process GO:0043433 negative regulation of DNA-binding transcription factor activity
Biological Process GO:0045930 negative regulation of mitotic cell cycle
Biological Process GO:0042308 negative regulation of protein import into nucleus
Biological Process GO:0045892 negative regulation of transcription, DNA-templated
Biological Process GO:0042532 negative regulation of tyrosine phosphorylation of STAT protein
Biological Process GO:0006591 ornithine metabolic process
Biological Process GO:0055091 phospholipid homeostasis
Biological Process GO:0045723 positive regulation of fatty acid biosynthetic process
Biological Process GO:0045722 positive regulation of gluconeogenesis
Biological Process GO:0045893 positive regulation of transcription, DNA-templated
Biological Process GO:0045944 positive regulation of transcription by RNA polymerase II
Biological Process GO:0042752 regulation of circadian rhythm
Biological Process GO:0010470 regulation of gastrulation
Biological Process GO:0050796 regulation of insulin secretion
Biological Process GO:0019216 regulation of lipid metabolic process
Biological Process GO:0032534 regulation of microvillus assembly
Biological Process GO:0006355 regulation of transcription, DNA-templated
Biological Process GO:0006357 regulation of transcription by RNA polymerase II
Biological Process GO:0051591 response to cAMP
Biological Process GO:0071548 response to dexamethasone
Biological Process GO:0042493 response to drug
Biological Process GO:0009749 response to glucose
Biological Process GO:0032496 response to lipopolysaccharide
Biological Process GO:0031667 response to nutrient levels
Biological Process GO:0048511 rhythmic process
Biological Process GO:0007548 sex differentiation
Biological Process GO:0023019 signal transduction involved in regulation of gene expression
Biological Process GO:0060395 SMAD protein signal transduction
Biological Process GO:0070328 triglyceride homeostasis
Biological Process GO:0003323 type B pancreatic cell development
Biological Process GO:0006805 xenobiotic metabolic process
molecular function GO:0050544 arachidonic acid binding
molecular function GO:0003682 chromatin binding
molecular function GO:0000987 cis-regulatory region sequence-specific DNA binding
molecular function GO:0003677 DNA binding
molecular function GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
molecular function GO:0003700 DNA-binding transcription factor activity
molecular function GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
molecular function GO:0005504 fatty acid binding
molecular function GO:0000062 fatty-acyl-CoA binding
molecular function GO:0036042 long-chain fatty acyl-CoA binding
molecular function GO:0016290 palmitoyl-CoA hydrolase activity
molecular function GO:0044877 protein-containing complex binding
molecular function GO:0042803 protein homodimerization activity
molecular function GO:0070491 repressing transcription factor binding
molecular function GO:0001102 RNA polymerase II activating transcription factor binding
molecular function GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
molecular function GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
molecular function GO:0043565 sequence-specific DNA binding
molecular function GO:0005102 signaling receptor binding
molecular function GO:0070540 stearic acid binding
molecular function GO:0008134 transcription factor binding
molecular function GO:0000976 transcription regulatory region sequence-specific DNA binding
molecular function GO:0008270 zinc ion binding
cellular component GO:0005737 cytoplasm
cellular component GO:0005634 nucleus
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002248 Dodecanoic acid 200.32
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein