Showing entry for Catechol O-methyltransferase


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT008799
Protein NameCatechol O-methyltransferase
Uniport IdP22734
GeneComt
Gene Id24267
DomainMethyltransf_3
Pfam PF01596  
OrganismRattus norvegicus (Rat)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0042424 catecholamine catabolic process
Biological Process GO:0009712 catechol-containing compound metabolic process
Biological Process GO:0016036 cellular response to phosphate starvation
Biological Process GO:0032502 developmental process
Biological Process GO:0042420 dopamine catabolic process
Biological Process GO:0042417 dopamine metabolic process
Biological Process GO:0008210 estrogen metabolic process
Biological Process GO:0007565 female pregnancy
Biological Process GO:0007612 learning
Biological Process GO:0032259 methylation
Biological Process GO:0048609 multicellular organismal reproductive process
Biological Process GO:0045963 negative regulation of dopamine metabolic process
Biological Process GO:0035814 negative regulation of renal sodium excretion
Biological Process GO:0048662 negative regulation of smooth muscle cell proliferation
Biological Process GO:0042135 neurotransmitter catabolic process
Biological Process GO:0050668 positive regulation of homocysteine metabolic process
Biological Process GO:0051930 regulation of sensory perception of pain
Biological Process GO:0042493 response to drug
Biological Process GO:0043627 response to estrogen
Biological Process GO:0032496 response to lipopolysaccharide
Biological Process GO:0014070 response to organic cyclic compound
Biological Process GO:0048265 response to pain
Biological Process GO:0046498 S-adenosylhomocysteine metabolic process
Biological Process GO:0046500 S-adenosylmethionine metabolic process
Biological Process GO:0007614 short-term memory
molecular function GO:0016206 catechol O-methyltransferase activity
molecular function GO:0102084 L-dopa O-methyltransferase activity
molecular function GO:0000287 magnesium ion binding
molecular function GO:0008171 O-methyltransferase activity
molecular function GO:0102938 orcinol O-methyltransferase activity
cellular component GO:0030424 axon
cellular component GO:0044297 cell body
cellular component GO:0005829 cytosol
cellular component GO:0030425 dendrite
cellular component GO:0043197 dendritic spine
cellular component GO:0016021 integral component of membrane
cellular component GO:0043231 intracellular membrane-bounded organelle
cellular component GO:0016020 membrane
cellular component GO:0045211 postsynaptic membrane
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000441 Dimethyl sulfoxide 78.13
BXGC0000485 3,5-Dihydroxy-4-methoxybenzaldehyde 168.15
BXGC0000516 Diosmetin 300.26
BXGC0000696 Tartaric acid 150.09
BXGC0001876 Chrysoeriol 300.26
BXGC0002588 Magnesium 24.31
BXGC0002591 Potassium 39.1
BXGC0003705 Chloride 35.45
BXGC0004266 2-Propanol 60.1
BXGC0005066 2R,3R-Butanediol 90.12
BXGC0006368 Formic acid 46.03
BXGC0014736 Isovanillin 152.05
BXGC0015880 3-Hydroxy-4,5-Dimethoxybenzoic Acid 198.05
BXGC0020437 EC-1-1 342.11
BXGC0031384 Epinephrine 183.09
BXGC0037943 isovanillic acid 168.04
BXGC0042127 Oxyquinoline 145.05
BXGC0049447 acetate 59.01
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein