protein

Showing entry for Furin

General Target Information
BXGT Id	BXGT008833
Protein Name	Furin
Uniport Id	P23188
Gene	Furin
Gene Id	18550
Domain	Peptidase_S8; P_proprotein; S8_pro-domain
Pfam	PF01483 PF00082 PF16470
Organism	Mus musculus (Mouse)

Target protein affiliated biological pathways

KEGG

Class	Subclass	KEGG Id	Pathway Name

Gene Ontology

GO Type	GO Id	Gene Ontology
Biological Process	GO:0001825	blastocyst formation
Biological Process	GO:0090472	dibasic protein processing
Biological Process	GO:0032804	negative regulation of low-density lipoprotein particle receptor catabolic process
Biological Process	GO:0032911	negative regulation of transforming growth factor beta1 production
Biological Process	GO:0032902	nerve growth factor production
Biological Process	GO:0043043	peptide biosynthetic process
Biological Process	GO:0016486	peptide hormone processing
Biological Process	GO:0030335	positive regulation of cell migration
Biological Process	GO:1901394	positive regulation of transforming growth factor beta1 activation
Biological Process	GO:0030511	positive regulation of transforming growth factor beta receptor signaling pathway
Biological Process	GO:0016485	protein processing
Biological Process	GO:0052548	regulation of endopeptidase activity
Biological Process	GO:0045714	regulation of low-density lipoprotein particle receptor biosynthetic process
Biological Process	GO:0042176	regulation of protein catabolic process
Biological Process	GO:0009966	regulation of signal transduction
Biological Process	GO:0032940	secretion by cell
Biological Process	GO:0006465	signal peptide processing
Biological Process	GO:0019058	viral life cycle
Biological Process	GO:0031638	zymogen activation
Biological Process	GO:0097341	zymogen inhibition
molecular function	GO:0004175	endopeptidase activity
molecular function	GO:0046872	metal ion binding
molecular function	GO:0048406	nerve growth factor binding
molecular function	GO:0008233	peptidase activity
molecular function	GO:0042277	peptide binding
molecular function	GO:0002020	protease binding
molecular function	GO:0004252	serine-type endopeptidase activity
molecular function	GO:0004867	serine-type endopeptidase inhibitor activity
cellular component	GO:0009986	cell surface
cellular component	GO:0005769	early endosome
cellular component	GO:0005783	endoplasmic reticulum
cellular component	GO:0005788	endoplasmic reticulum lumen
cellular component	GO:0005789	endoplasmic reticulum membrane
cellular component	GO:0010008	endosome membrane
cellular component	GO:0005576	extracellular region
cellular component	GO:0031985	Golgi cisterna
cellular component	GO:0000139	Golgi membrane
cellular component	GO:0030173	integral component of Golgi membrane
cellular component	GO:0016021	integral component of membrane
cellular component	GO:0016020	membrane
cellular component	GO:0045121	membrane raft
cellular component	GO:0005886	plasma membrane
cellular component	GO:0005802	trans-Golgi network
cellular component	GO:0030140	trans-Golgi network transport vesicle
cellular component	GO:0012510	trans-Golgi network transport vesicle membrane

Reactome

Pathway Id	Pathway Name

Target protein-related diseases

Disease

CUI Id	BXGD Id	Disease Name	Disease Class

Target protein-related compounds

Compounds

BXGC Id	Compound Name	Strcuture	Molecular Weight
BXGC0002586	Calcium		40.08
BXGC0018397	beta-1,4-mannan		180.06
BXGC0050194	alpha-D-Mannose		180.06

The target protein-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compound^{? Number of compound in food, higher numbers indicate the food are more associated with the protein}