Showing entry for Major prion protein


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT008924
Protein NameMajor prion protein
Uniport IdP23907
GenePRNP
Gene Id493887
DomainPrion; Prion_bPrPp
Pfam PF00377   PF11587  
OrganismOvis aries (Sheep)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0035584 calcium-mediated signaling using intracellular calcium source
Biological Process GO:1904646 cellular response to amyloid-beta
Biological Process GO:0071280 cellular response to copper ion
Biological Process GO:0010951 negative regulation of endopeptidase activity
Biological Process GO:0043525 positive regulation of neuron apoptotic process
Biological Process GO:0061098 positive regulation of protein tyrosine kinase activity
Biological Process GO:0031648 protein destabilization
Biological Process GO:0051260 protein homooligomerization
Biological Process GO:1902938 regulation of intracellular calcium activated chloride channel activity
molecular function GO:0001540 amyloid-beta binding
molecular function GO:0005507 copper ion binding
molecular function GO:1903136 cuprous ion binding
molecular function GO:0042802 identical protein binding
molecular function GO:0008017 microtubule binding
molecular function GO:0044877 protein-containing complex binding
molecular function GO:0015631 tubulin binding
molecular function GO:0031802 type 5 metabotropic glutamate receptor binding
cellular component GO:0031225 anchored component of membrane
cellular component GO:0009986 cell surface
cellular component GO:0005829 cytosol
cellular component GO:0030425 dendrite
cellular component GO:0005794 Golgi apparatus
cellular component GO:0016234 inclusion body
cellular component GO:0045121 membrane raft
cellular component GO:0031965 nuclear membrane
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000989 Glutathione 307.32
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein