Showing entry for Sodium-dependent dopamine transporter



                       
General Target Information
BXGT IdBXGT008936
Protein NameSodium-dependent dopamine transporter
Uniport IdP23977
GeneSlc6a3
Gene Id24898
DomainSNF
Pfam PF00209  
OrganismRattus norvegicus (Rat)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0021984 adenohypophysis development
Biological Process GO:0007568 aging
Biological Process GO:0042416 dopamine biosynthetic process
Biological Process GO:0042420 dopamine catabolic process
Biological Process GO:0015872 dopamine transport
Biological Process GO:0090494 dopamine uptake
Biological Process GO:0051583 dopamine uptake involved in synaptic transmission
Biological Process GO:1990384 hyaloid vascular plexus regression
Biological Process GO:0007595 lactation
Biological Process GO:0007626 locomotory behavior
Biological Process GO:0015844 monoamine transport
Biological Process GO:0001504 neurotransmitter uptake
Biological Process GO:0015874 norepinephrine transport
Biological Process GO:0040018 positive regulation of multicellular organism growth
Biological Process GO:0060134 prepulse inhibition
Biological Process GO:0042053 regulation of dopamine metabolic process
Biological Process GO:0051591 response to cAMP
Biological Process GO:0042220 response to cocaine
Biological Process GO:0042493 response to drug
Biological Process GO:0045471 response to ethanol
Biological Process GO:0010039 response to iron ion
Biological Process GO:0035094 response to nicotine
Biological Process GO:0014070 response to organic cyclic compound
Biological Process GO:0007608 sensory perception of smell
molecular function GO:0005330 dopamine:sodium symporter activity
molecular function GO:0035240 dopamine binding
molecular function GO:0008144 drug binding
molecular function GO:0046872 metal ion binding
molecular function GO:0008504 monoamine transmembrane transporter activity
molecular function GO:0005326 neurotransmitter transmembrane transporter activity
molecular function GO:0005334 norepinephrine:sodium symporter activity
molecular function GO:0002020 protease binding
molecular function GO:0044877 protein-containing complex binding
molecular function GO:0047485 protein N-terminus binding
molecular function GO:0051721 protein phosphatase 2A binding
molecular function GO:0005102 signaling receptor binding
cellular component GO:0030424 axon
cellular component GO:0009986 cell surface
cellular component GO:0016600 flotillin complex
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0045121 membrane raft
cellular component GO:0043025 neuronal cell body
cellular component GO:0032809 neuronal cell body membrane
cellular component GO:0043005 neuron projection
cellular component GO:0005886 plasma membrane
cellular component GO:0042734 presynaptic membrane
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000191 Tyramine 137.18
BXGC0000538 (R)-Norepinephrine 169.18
BXGC0000548 Tryptamine 160.22
BXGC0000653 1,2,3,4-Tetrahydro-2-methyl-b-carboline 186.25
BXGC0000994 Liriodenine 275.26
BXGC0003845 But-3-en-2-one 70.09
BXGC0004283 2-Propenal 56.06
BXGC0005645 Quinoline 129.16
BXGC0005867 Serotonin 176.22
BXGC0005871 Dopamine 153.18
BXGC0006635 Luteolin 286.24
BXGC0012888 2-Methyl-3,4-Dihydro-1H-Isoquinoline 147.1
BXGC0013581 Isotetrandrine 622.3
BXGC0014063 Norstephalagine 295.12
BXGC0014068 Amphetamine 135.1
BXGC0014893 2,3-Dimethoxy-6-Methyl-5,6,6A,7-Tetrahydro-4H-Dibenzo[De,G]Quinolin-1-Ol 311.15
BXGC0016891 Nortriptyline 263.17
BXGC0018317 isoquinoline 129.06
BXGC0019520 Anolobine 281.11
BXGC0021893 Norepinephrine 169.07
BXGC0022524 Isopiline 297.14
BXGC0024748 Anonaine 265.11
BXGC0027312 Norarmepavine 299.15
BXGC0027700 Lysicamine 291.09
BXGC0029047 9H-Fluoren-9-Ol 182.07
BXGC0030110 (-)-ephedrinium 166.12
BXGC0031211 3-Phenylpiperidine 161.12
BXGC0034371 1,2,3,4-Tetrahydroisoquinoline 133.09
BXGC0034961 Norboldine 313.13
BXGC0035865 (+)-Pentazocine 285.21
BXGC0036175 Homoaromoline 608.29
BXGC0037084 L-Coclaurine 285.14
BXGC0042510 Fluoxetine 309.13
BXGC0042562 Acrylamide 71.04
BXGC0042574 Ibogaine 310.2
BXGC0046755 Yohimbine 354.19
BXGC0048699 Obaberine 622.3
BXGC0051494 Rel-Pentazocine 285.21
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein