Showing entry for Corticotropin-releasing factor-binding protein


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT008966
Protein NameCorticotropin-releasing factor-binding protein
Uniport IdP24387
GeneCRHBP
Gene Id1393
DomainCRF-BP
Pfam PF05428  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0048149 behavioral response to ethanol
Biological Process GO:0071277 cellular response to calcium ion
Biological Process GO:0071320 cellular response to cAMP
Biological Process GO:0071314 cellular response to cocaine
Biological Process GO:0035690 cellular response to drug
Biological Process GO:0071392 cellular response to estradiol stimulus
Biological Process GO:0071391 cellular response to estrogen stimulus
Biological Process GO:0097211 cellular response to gonadotropin-releasing hormone
Biological Process GO:0035865 cellular response to potassium ion
Biological Process GO:0071356 cellular response to tumor necrosis factor
Biological Process GO:0007565 female pregnancy
Biological Process GO:0009755 hormone-mediated signaling pathway
Biological Process GO:0042445 hormone metabolic process
Biological Process GO:0006954 inflammatory response
Biological Process GO:0007611 learning or memory
Biological Process GO:0002125 maternal aggressive behavior
Biological Process GO:1900011 negative regulation of corticotropin-releasing hormone receptor activity
Biological Process GO:0051460 negative regulation of corticotropin secretion
Biological Process GO:0045055 regulated exocytosis
Biological Process GO:0080135 regulation of cellular response to stress
Biological Process GO:0051459 regulation of corticotropin secretion
Biological Process GO:2000310 regulation of NMDA receptor activity
Biological Process GO:0007165 signal transduction
Biological Process GO:0001963 synaptic transmission, dopaminergic
molecular function GO:0051424 corticotropin-releasing hormone binding
molecular function GO:0042277 peptide binding
cellular component GO:0043679 axon terminus
cellular component GO:0030425 dendrite
cellular component GO:0031045 dense core granule
cellular component GO:0005576 extracellular region
cellular component GO:0005615 extracellular space
cellular component GO:0005874 microtubule
cellular component GO:0005771 multivesicular body
cellular component GO:0005634 nucleus
cellular component GO:0043204 perikaryon
cellular component GO:0005767 secondary lysosome
cellular component GO:0030141 secretory granule
cellular component GO:0043196 varicosity
Reactome
Pathway Id Pathway Name
R-HSA-162582 Signal Transduction
R-HSA-372790 Signaling by GPCR
R-HSA-373080 Class B/2 (Secretin family receptors)
R-HSA-500792 GPCR ligand binding
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001956 BXGD000092 Alcohol Use Disorder Chemically-Induced Disorders; Mental Disorders
C0001973 BXGD000095 Alcoholic Intoxication, Chronic Chemically-Induced Disorders; Mental Disorders
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0003467 BXGD000194 Anxiety Behavior and Behavior Mechanisms
C0003469 BXGD000195 Anxiety Disorders Mental Disorders
C0004936 BXGD000295 Mental disorders Mental Disorders
C0005586 BXGD000315 Bipolar Disorder Mental Disorders
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007134 BXGD000443 Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0007682 BXGD000471 CNS disorder Nervous System Diseases
C0009171 BXGD000587 Cocaine Abuse Chemically-Induced Disorders; Mental Disorders
C0011570 BXGD000729 Mental Depression Behavior and Behavior Mechanisms
C0011581 BXGD000733 Depressive disorder Mental Disorders
C0014556 BXGD000932 Epilepsy, Temporal Lobe Nervous System Diseases
C0019163 BXGD001295 Hepatitis B Digestive System Diseases; Infections
C0019337 BXGD001319 Heroin Dependence Chemically-Induced Disorders; Mental Disorders
C0022104 BXGD001529 Irritable Bowel Syndrome Digestive System Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0028047 BXGD002067 Nicotine withdrawal Chemically-Induced Disorders; Mental Disorders
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0030193 BXGD002191 Pain Pathological Conditions, Signs and Symptoms
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0038441 BXGD002756 Stress Disorders, Traumatic Mental Disorders
C0038443 BXGD002757 Stress, Psychological Behavior and Behavior Mechanisms
C0038454 BXGD002760 Cerebrovascular accident Nervous System Diseases; Cardiovascular Diseases
C0041696 BXGD002932 Unipolar Depression Mental Disorders
C0085281 BXGD003152 Addictive Behavior Behavior and Behavior Mechanisms
C0086132 BXGD003264 Depressive Symptoms Behavior and Behavior Mechanisms
C0150055 BXGD003401 Chronic pain Pathological Conditions, Signs and Symptoms
C0154409 BXGD003717 Recurrent major depressive episodes Mental Disorders
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0206081 BXGD004152 Hyperandrogenism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0221406 BXGD004459 Pituitary-dependent Cushing's disease Nervous System Diseases; Endocrine System Diseases
C0236736 BXGD004825 Cocaine-Related Disorders Chemically-Induced Disorders; Mental Disorders
C0279702 BXGD006685 Conventional (Clear Cell) Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0344315 BXGD007666 Depressed mood Behavior and Behavior Mechanisms
C0525045 BXGD009255 Mood Disorders Mental Disorders
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0600427 BXGD009706 Cocaine Dependence Chemically-Induced Disorders; Mental Disorders
C0740457 BXGD010000 Malignant neoplasm of kidney Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0871388 BXGD011314 social stress Behavior and Behavior Mechanisms
C1269683 BXGD012001 Major Depressive Disorder Mental Disorders
C1306214 BXGD012356 ACTH-Secreting Pituitary Adenoma Neoplasms; Nervous System Diseases; Endocrine System Diseases
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1378703 BXGD012933 Renal carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C3178789 BXGD018537 Widespread Chronic Pain Pathological Conditions, Signs and Symptoms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0001200 3-Hydroxy-4-isopentenyl-5-methoxybibenzyl-2-carboxylic acid 340.41
BXGC0016973 Guvacine Hydrochloride 127.06
BXGC0022806 1-(5-Thiophen-2-Ylthiophen-2-Yl)Ethanone 208
BXGC0023490 saikosaponin 780.47
BXGC0036632 Austrobailignan 6 328.17
BXGC0044598 Guvacine 127.06
BXGC0044812 Sid14737105 261.14
BXGC0052566 Sid22414536 180.04
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein