Showing entry for Agrin


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT009033
Protein NameAgrin
Uniport IdP25304
GeneAgrn
Gene Id25592
DomainEGF; Kazal_1; Kazal_2; Laminin_EGF; Laminin_G_1; SEA
Pfam PF00008   PF00050   PF07648   PF00053   PF00054   PF01390  
OrganismRattus norvegicus (Rat)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0009887 animal organ morphogenesis
Biological Process GO:0007268 chemical synaptic transmission
Biological Process GO:1903407 negative regulation of sodium:potassium-exchanging ATPase activity
Biological Process GO:1903277 negative regulation of sodium ion export across plasma membrane
Biological Process GO:0007528 neuromuscular junction development
Biological Process GO:0045213 neurotransmitter receptor metabolic process
Biological Process GO:0007009 plasma membrane organization
Biological Process GO:0051491 positive regulation of filopodium assembly
Biological Process GO:0043547 positive regulation of GTPase activity
Biological Process GO:0043525 positive regulation of neuron apoptotic process
Biological Process GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation
Biological Process GO:0032092 positive regulation of protein binding
Biological Process GO:2000541 positive regulation of protein geranylgeranylation
Biological Process GO:0001934 positive regulation of protein phosphorylation
Biological Process GO:0061098 positive regulation of protein tyrosine kinase activity
Biological Process GO:0045887 positive regulation of synaptic growth at neuromuscular junction
Biological Process GO:0045944 positive regulation of transcription by RNA polymerase II
Biological Process GO:0043113 receptor clustering
Biological Process GO:1902667 regulation of axon guidance
Biological Process GO:0086036 regulation of cardiac muscle cell membrane potential
Biological Process GO:0055117 regulation of cardiac muscle contraction
Biological Process GO:0043087 regulation of GTPase activity
Biological Process GO:0070507 regulation of microtubule cytoskeleton organization
Biological Process GO:0001932 regulation of protein phosphorylation
Biological Process GO:0008582 regulation of synaptic growth at neuromuscular junction
Biological Process GO:0071340 skeletal muscle acetylcholine-gated channel clustering
Biological Process GO:0007416 synapse assembly
Biological Process GO:0009888 tissue development
molecular function GO:0030548 acetylcholine receptor regulator activity
molecular function GO:0042030 ATPase inhibitor activity
molecular function GO:0036122 BMP binding
molecular function GO:0005509 calcium ion binding
molecular function GO:0035374 chondroitin sulfate binding
molecular function GO:0002162 dystroglycan binding
molecular function GO:0043395 heparan sulfate proteoglycan binding
molecular function GO:0044325 ion channel binding
molecular function GO:0033691 sialic acid binding
molecular function GO:0050431 transforming growth factor beta binding
cellular component GO:0044295 axonal growth cone
cellular component GO:0005604 basement membrane
cellular component GO:0009986 cell surface
cellular component GO:0062023 collagen-containing extracellular matrix
cellular component GO:0031012 extracellular matrix
cellular component GO:0005576 extracellular region
cellular component GO:0005615 extracellular space
cellular component GO:0016021 integral component of membrane
cellular component GO:0042383 sarcolemma
cellular component GO:0045202 synapse
cellular component GO:0043083 synaptic cleft
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002586 Calcium 40.08
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein