Showing entry for Endothelin-1 receptor



                       
General Target Information
BXGT IdBXGT009130
Protein NameEndothelin-1 receptor
Uniport IdP26684
GeneEdnra
Gene Id24326
Domain7tm_1
Pfam PF00001  
OrganismRattus norvegicus (Rat)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007193 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway
Biological Process GO:0007568 aging
Biological Process GO:0014824 artery smooth muscle contraction
Biological Process GO:0001569 branching involved in blood vessel morphogenesis
Biological Process GO:0071260 cellular response to mechanical stimulus
Biological Process GO:0048484 enteric nervous system development
Biological Process GO:0048144 fibroblast proliferation
Biological Process GO:0003094 glomerular filtration
Biological Process GO:0060322 head development
Biological Process GO:0007507 heart development
Biological Process GO:0001821 histamine secretion
Biological Process GO:0001701 in utero embryonic development
Biological Process GO:0060137 maternal process involved in parturition
Biological Process GO:0043066 negative regulation of apoptotic process
Biological Process GO:0014032 neural crest cell development
Biological Process GO:0043084 penile erection
Biological Process GO:0051928 positive regulation of calcium ion transport
Biological Process GO:0008284 positive regulation of cell population proliferation
Biological Process GO:0007204 positive regulation of cytosolic calcium ion concentration
Biological Process GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway
Biological Process GO:0070374 positive regulation of ERK1 and ERK2 cascade
Biological Process GO:0050729 positive regulation of inflammatory response
Biological Process GO:0090184 positive regulation of kidney development
Biological Process GO:0090023 positive regulation of neutrophil chemotaxis
Biological Process GO:0042482 positive regulation of odontogenesis
Biological Process GO:0001934 positive regulation of protein phosphorylation
Biological Process GO:0051281 positive regulation of release of sequestered calcium ion into cytosol
Biological Process GO:0007205 protein kinase C-activating G protein-coupled receptor signaling pathway
Biological Process GO:0050678 regulation of epithelial cell proliferation
Biological Process GO:0010827 regulation of glucose transmembrane transport
Biological Process GO:0007585 respiratory gaseous exchange by respiratory system
Biological Process GO:0001666 response to hypoxia
Biological Process GO:0032496 response to lipopolysaccharide
Biological Process GO:0043278 response to morphine
Biological Process GO:0014070 response to organic cyclic compound
Biological Process GO:0007266 Rho protein signal transduction
Biological Process GO:0019233 sensory perception of pain
Biological Process GO:0048659 smooth muscle cell proliferation
Biological Process GO:0042310 vasoconstriction
molecular function GO:0004962 endothelin receptor activity
cellular component GO:0016021 integral component of membrane
cellular component GO:0016020 membrane
cellular component GO:0031965 nuclear membrane
cellular component GO:0030315 T-tubule
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0051235 Phyllanthin 418.24
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein