Showing entry for Ras-specific guanine nucleotide-releasing factor 1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT009195
Protein NameRas-specific guanine nucleotide-releasing factor 1
Uniport IdP27671
GeneRasgrf1
Gene Id19417
DomainPH; RasGEF; RasGEF_N; RhoGEF
Pfam PF00169   PF00617   PF00618   PF00621  
OrganismMus musculus (Mouse)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0090630 activation of GTPase activity
Biological Process GO:0008283 cell population proliferation
Biological Process GO:0031175 neuron projection development
Biological Process GO:0048146 positive regulation of fibroblast proliferation
Biological Process GO:0043547 positive regulation of GTPase activity
Biological Process GO:0046579 positive regulation of Ras protein signal transduction
Biological Process GO:0048168 regulation of neuronal synaptic plasticity
Biological Process GO:2000310 regulation of NMDA receptor activity
Biological Process GO:0035020 regulation of Rac protein signal transduction
Biological Process GO:0046578 regulation of Ras protein signal transduction
Biological Process GO:0035023 regulation of Rho protein signal transduction
Biological Process GO:0048167 regulation of synaptic plasticity
Biological Process GO:0034976 response to endoplasmic reticulum stress
Biological Process GO:0007264 small GTPase mediated signal transduction
molecular function GO:0035254 glutamate receptor binding
molecular function GO:0008022 protein C-terminus binding
molecular function GO:0019901 protein kinase binding
molecular function GO:0017016 Ras GTPase binding
molecular function GO:0005088 Ras guanyl-nucleotide exchange factor activity
molecular function GO:0030971 receptor tyrosine kinase binding
cellular component GO:0097440 apical dendrite
cellular component GO:0016327 apicolateral plasma membrane
cellular component GO:0016323 basolateral plasma membrane
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0030426 growth cone
cellular component GO:0043025 neuronal cell body
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein