Showing entry for 5-hydroxytryptamine receptor 1B


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT009254
Protein Name5-hydroxytryptamine receptor 1B
Uniport IdP28334
GeneHtr1b
Gene Id15551
Domain7tm_1
Pfam PF00001  
OrganismMus musculus (Mouse)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007193 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway
Biological Process GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway
Biological Process GO:0046849 bone remodeling
Biological Process GO:0071312 cellular response to alkaloid
Biological Process GO:0035690 cellular response to drug
Biological Process GO:0071502 cellular response to temperature stimulus
Biological Process GO:0007268 chemical synaptic transmission
Biological Process GO:0042756 drinking behavior
Biological Process GO:0007631 feeding behavior
Biological Process GO:0002031 G protein-coupled receptor internalization
Biological Process GO:0007187 G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
Biological Process GO:0014053 negative regulation of gamma-aminobutyric acid secretion
Biological Process GO:0014063 negative regulation of serotonin secretion
Biological Process GO:0032229 negative regulation of synaptic transmission, GABAergic
Biological Process GO:0051967 negative regulation of synaptic transmission, glutamatergic
Biological Process GO:1904707 positive regulation of vascular associated smooth muscle cell proliferation
Biological Process GO:0099171 presynaptic modulation of chemical synaptic transmission
Biological Process GO:0007205 protein kinase C-activating G protein-coupled receptor signaling pathway
Biological Process GO:0050795 regulation of behavior
Biological Process GO:0014059 regulation of dopamine secretion
Biological Process GO:2000300 regulation of synaptic vesicle exocytosis
Biological Process GO:0042220 response to cocaine
Biological Process GO:0042493 response to drug
Biological Process GO:0045471 response to ethanol
Biological Process GO:0051385 response to mineralocorticoid
Biological Process GO:0042310 vasoconstriction
molecular function GO:0008144 drug binding
molecular function GO:0004930 G protein-coupled receptor activity
molecular function GO:0004993 G protein-coupled serotonin receptor activity
molecular function GO:0030594 neurotransmitter receptor activity
molecular function GO:0051378 serotonin binding
molecular function GO:0099626 voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels
cellular component GO:0044305 calyx of Held
cellular component GO:0005737 cytoplasm
cellular component GO:0030425 dendrite
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0099056 integral component of presynaptic membrane
cellular component GO:0005886 plasma membrane
cellular component GO:0099154 serotonergic synapse
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0005867 Serotonin 176.22
BXGC0046755 Yohimbine 354.19
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein