Showing entry for Granulocyte-macrophage colony-stimulating factor


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT009289
Protein NameGranulocyte-macrophage colony-stimulating factor
Uniport IdP28773
GeneCSF2
Gene Id443400
DomainGM_CSF
Pfam PF01109  
OrganismOvis aries (Sheep)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus
Biological Process GO:0001892 embryonic placenta development
Biological Process GO:0006955 immune response
Biological Process GO:0030225 macrophage differentiation
Biological Process GO:0030224 monocyte differentiation
Biological Process GO:0043011 myeloid dendritic cell differentiation
Biological Process GO:2001240 negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
Biological Process GO:0045892 negative regulation of transcription, DNA-templated
Biological Process GO:0030223 neutrophil differentiation
Biological Process GO:0008284 positive regulation of cell population proliferation
Biological Process GO:0032747 positive regulation of interleukin-23 production
Biological Process GO:0010744 positive regulation of macrophage derived foam cell differentiation
Biological Process GO:0071803 positive regulation of podosome assembly
Biological Process GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein
molecular function GO:0005125 cytokine activity
molecular function GO:0005129 granulocyte macrophage colony-stimulating factor receptor binding
molecular function GO:0008083 growth factor activity
cellular component GO:0005615 extracellular space
cellular component GO:0043231 intracellular membrane-bounded organelle
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0049447 acetate 59.01
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein