protein

Showing entry for Indoleamine 2,3-dioxygenase 1

General Target Information
BXGT Id	BXGT009290
Protein Name	Indoleamine 2,3-dioxygenase 1
Uniport Id	P28776
Gene	Ido1
Gene Id	15930
Domain	IDO
Pfam	PF01231
Organism	Mus musculus (Mouse)

Target protein affiliated biological pathways

KEGG

Class	Subclass	KEGG Id	Pathway Name

Gene Ontology

GO Type	GO Id	Gene Ontology
Biological Process	GO:0034354	'de novo' NAD biosynthetic process from tryptophan
Biological Process	GO:0002534	cytokine production involved in inflammatory response
Biological Process	GO:0006952	defense response
Biological Process	GO:0002376	immune system process
Biological Process	GO:0006954	inflammatory response
Biological Process	GO:0034276	kynurenic acid biosynthetic process
Biological Process	GO:0033555	multicellular organismal response to stress
Biological Process	GO:0046007	negative regulation of activated T cell proliferation
Biological Process	GO:0032693	negative regulation of interleukin-10 production
Biological Process	GO:0070233	negative regulation of T cell apoptotic process
Biological Process	GO:0042130	negative regulation of T cell proliferation
Biological Process	GO:0043065	positive regulation of apoptotic process
Biological Process	GO:0002678	positive regulation of chronic inflammatory response
Biological Process	GO:0032735	positive regulation of interleukin-12 production
Biological Process	GO:0070234	positive regulation of T cell apoptotic process
Biological Process	GO:0002666	positive regulation of T cell tolerance induction
Biological Process	GO:0002830	positive regulation of type 2 immune response
Biological Process	GO:0032496	response to lipopolysaccharide
Biological Process	GO:0036269	swimming behavior
Biological Process	GO:0019441	tryptophan catabolic process to kynurenine
molecular function	GO:0016597	amino acid binding
molecular function	GO:0020037	heme binding
molecular function	GO:0033754	indoleamine 2,3-dioxygenase activity
molecular function	GO:0046872	metal ion binding
molecular function	GO:0019825	oxygen binding
molecular function	GO:0004833	tryptophan 2,3-dioxygenase activity
cellular component	GO:0005737	cytoplasm
cellular component	GO:0005829	cytosol
cellular component	GO:0030485	smooth muscle contractile fiber
cellular component	GO:0032421	stereocilium bundle

Reactome

Pathway Id	Pathway Name

Target protein-related diseases

Disease

CUI Id	BXGD Id	Disease Name	Disease Class

Target protein-related compounds

Compounds

BXGC Id	Compound Name	Strcuture	Molecular Weight
BXGC0003502	Phenylhydrazine		108.14
BXGC0024988	Nifedipine		346.12
BXGC0031072	Naphthalene-1,4-Diol		160.05

The target protein-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compound^{? Number of compound in food, higher numbers indicate the food are more associated with the protein}