Showing entry for Receptor-type tyrosine-protein phosphatase mu


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT009293
Protein NameReceptor-type tyrosine-protein phosphatase mu
Uniport IdP28827
GenePTPRM
Gene Id5797
Domainfn3; ig; MAM; Y_phosphatase
Pfam PF00041   PF00047   PF00629   PF00102  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
3. Environmental Information Processing 3.3 Signaling molecules and interaction hsa04514 Cell adhesion molecules (CAMs)
4. Cellular Processes 4.3 Cellular community - eukaryotes hsa04520 Adherens junction
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules
Biological Process GO:0016525 negative regulation of angiogenesis
Biological Process GO:0010596 negative regulation of endothelial cell migration
Biological Process GO:0001937 negative regulation of endothelial cell proliferation
Biological Process GO:0031175 neuron projection development
Biological Process GO:0097755 positive regulation of blood vessel diameter
Biological Process GO:0006470 protein dephosphorylation
Biological Process GO:0042493 response to drug
Biological Process GO:0010842 retina layer formation
Biological Process GO:0031290 retinal ganglion cell axon guidance
Biological Process GO:0007165 signal transduction
molecular function GO:0045296 cadherin binding
molecular function GO:0042802 identical protein binding
molecular function GO:0004725 protein tyrosine phosphatase activity
molecular function GO:0005001 transmembrane receptor protein tyrosine phosphatase activity
cellular component GO:0005912 adherens junction
cellular component GO:0005911 cell-cell junction
cellular component GO:0005737 cytoplasm
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0030027 lamellipodium
cellular component GO:0048471 perinuclear region of cytoplasm
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001430 BXGD000054 Adenoma Neoplasms
C0004364 BXGD000270 Autoimmune Diseases Immune System Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0007097 BXGD000424 Carcinoma Neoplasms
C0007102 BXGD000425 Malignant tumor of colon Digestive System Diseases; Neoplasms
C0026769 BXGD001930 Multiple Sclerosis Immune System Diseases; Nervous System Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0036868 BXGD002639 Sex Chromosome Aberrations Pathological Conditions, Signs and Symptoms
C0206754 BXGD004289 Neuroendocrine Tumors Neoplasms
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0699790 BXGD009866 Colon Carcinoma Digestive System Diseases; Neoplasms
C1266708 BXGD011994 Polybrominated biphenyl measurement
C1269955 BXGD012005 Tumor Cell Invasion
C1302401 BXGD012303 Adenoma of large intestine Digestive System Diseases; Neoplasms
C2939419 BXGD018178 Secondary Neoplasm Pathological Conditions, Signs and Symptoms; Neoplasms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0050194 alpha-D-Mannose 180.06
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein