Showing entry for Beta-arrestin-1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT009310
Protein NameBeta-arrestin-1
Uniport IdP29066
GeneArrb1
Gene Id25387
DomainArrestin_C; Arrestin_N
Pfam PF02752   PF00339  
OrganismRattus norvegicus (Rat)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0000187 activation of MAPK activity
Biological Process GO:0007188 adenylate cyclase-modulating G protein-coupled receptor signaling pathway
Biological Process GO:0006897 endocytosis
Biological Process GO:0042699 follicle-stimulating hormone signaling pathway
Biological Process GO:0002031 G protein-coupled receptor internalization
Biological Process GO:0007186 G protein-coupled receptor signaling pathway
Biological Process GO:0016573 histone acetylation
Biological Process GO:0043066 negative regulation of apoptotic process
Biological Process GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
Biological Process GO:0070373 negative regulation of ERK1 and ERK2 cascade
Biological Process GO:0034260 negative regulation of GTPase activity
Biological Process GO:0032715 negative regulation of interleukin-6 production
Biological Process GO:0032717 negative regulation of interleukin-8 production
Biological Process GO:0043524 negative regulation of neuron apoptotic process
Biological Process GO:0032088 negative regulation of NF-kappaB transcription factor activity
Biological Process GO:0045746 negative regulation of Notch signaling pathway
Biological Process GO:0001933 negative regulation of protein phosphorylation
Biological Process GO:0031397 negative regulation of protein ubiquitination
Biological Process GO:0007602 phototransduction
Biological Process GO:0008284 positive regulation of cell population proliferation
Biological Process GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
Biological Process GO:0070374 positive regulation of ERK1 and ERK2 cascade
Biological Process GO:0035066 positive regulation of histone acetylation
Biological Process GO:0090240 positive regulation of histone H4 acetylation
Biological Process GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus
Biological Process GO:0033138 positive regulation of peptidyl-serine phosphorylation
Biological Process GO:0032092 positive regulation of protein binding
Biological Process GO:0001934 positive regulation of protein phosphorylation
Biological Process GO:0031398 positive regulation of protein ubiquitination
Biological Process GO:0002092 positive regulation of receptor internalization
Biological Process GO:0035025 positive regulation of Rho protein signal transduction
Biological Process GO:0034393 positive regulation of smooth muscle cell apoptotic process
Biological Process GO:0045944 positive regulation of transcription by RNA polymerase II
Biological Process GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
Biological Process GO:0015031 protein transport
Biological Process GO:0016567 protein ubiquitination
Biological Process GO:0042981 regulation of apoptotic process
Biological Process GO:0008277 regulation of G protein-coupled receptor signaling pathway
Biological Process GO:0006355 regulation of transcription, DNA-templated
Biological Process GO:0042493 response to drug
Biological Process GO:0019233 sensory perception of pain
Biological Process GO:0050975 sensory perception of touch
Biological Process GO:0043149 stress fiber assembly
Biological Process GO:0006366 transcription by RNA polymerase II
Biological Process GO:0006511 ubiquitin-dependent protein catabolic process
molecular function GO:0031691 alpha-1A adrenergic receptor binding
molecular function GO:0031692 alpha-1B adrenergic receptor binding
molecular function GO:0031701 angiotensin receptor binding
molecular function GO:0035612 AP-2 adaptor complex binding
molecular function GO:1990763 arrestin family protein binding
molecular function GO:0035615 clathrin adaptor activity
molecular function GO:0030276 clathrin binding
molecular function GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process
molecular function GO:0019899 enzyme binding
molecular function GO:0030331 estrogen receptor binding
molecular function GO:0031762 follicle-stimulating hormone receptor binding
molecular function GO:0001664 G protein-coupled receptor binding
molecular function GO:0005096 GTPase activator activity
molecular function GO:0005159 insulin-like growth factor receptor binding
molecular function GO:0044325 ion channel binding
molecular function GO:0031434 mitogen-activated protein kinase kinase binding
molecular function GO:0051219 phosphoprotein binding
molecular function GO:0045309 protein phosphorylated amino acid binding
molecular function GO:0005102 signaling receptor binding
molecular function GO:0003713 transcription coactivator activity
molecular function GO:0008134 transcription factor binding
molecular function GO:0000976 transcription regulatory region sequence-specific DNA binding
molecular function GO:0031625 ubiquitin protein ligase binding
molecular function GO:0031896 V2 vasopressin receptor binding
cellular component GO:0016323 basolateral plasma membrane
cellular component GO:0000785 chromatin
cellular component GO:0005905 clathrin-coated pit
cellular component GO:0005737 cytoplasm
cellular component GO:0031410 cytoplasmic vesicle
cellular component GO:0005829 cytosol
cellular component GO:0043197 dendritic spine
cellular component GO:0005768 endosome
cellular component GO:0016604 nuclear body
cellular component GO:0005634 nucleus
cellular component GO:0005886 plasma membrane
cellular component GO:0014069 postsynaptic density
cellular component GO:0045211 postsynaptic membrane
cellular component GO:0031143 pseudopodium
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0003705 Chloride 35.45
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein