Showing entry for Interleukin-12 subunit beta


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT009348
Protein NameInterleukin-12 subunit beta
Uniport IdP29460
GeneIL12B
Gene Id3593
DomainIL12p40_C
Pfam PF10420  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
3. Environmental Information Processing 3.3 Signaling molecules and interaction hsa04060 Cytokine-cytokine receptor interaction
5. Organismal Systems 5.1 Immune system hsa04620 Toll-like receptor signaling pathway
5. Organismal Systems 5.1 Immune system hsa04622 RIG-I-like receptor signaling pathway
5. Organismal Systems 5.1 Immune system hsa04625 C-type lectin receptor signaling pathway
3. Environmental Information Processing 3.2 Signal transduction hsa04630 Jak-STAT signaling pathway
5. Organismal Systems 5.1 Immune system hsa04658 Th1 and Th2 cell differentiation
6. Human Diseases 6.7 Endocrine and metabolic diseases hsa04940 Type I diabetes mellitus
6. Human Diseases 6.8 Infectious diseases: Bacterial hsa05133 Pertussis
6. Human Diseases 6.8 Infectious diseases: Bacterial hsa05134 Legionellosis
6. Human Diseases 6.10 Infectious diseases: Parasitic hsa05140 Leishmaniasis
6. Human Diseases 6.10 Infectious diseases: Parasitic hsa05142 Chagas disease (American trypanosomiasis)
6. Human Diseases 6.10 Infectious diseases: Parasitic hsa05143 African trypanosomiasis
6. Human Diseases 6.10 Infectious diseases: Parasitic hsa05145 Toxoplasmosis
6. Human Diseases 6.10 Infectious diseases: Parasitic hsa05146 Amoebiasis
6. Human Diseases 6.8 Infectious diseases: Bacterial hsa05152 Tuberculosis
6. Human Diseases 6.9 Infectious diseases: Viral hsa05162 Measles
6. Human Diseases 6.9 Infectious diseases: Viral hsa05164 Influenza A
6. Human Diseases 6.9 Infectious diseases: Viral hsa05168 Herpes simplex virus 1 infection
6. Human Diseases 6.1 Cancers: Overview hsa05200 Pathways in cancer
6. Human Diseases 6.1 Cancers: Overview hsa05205 Proteoglycans in cancer
6. Human Diseases 6.3 Immune diseases hsa05321 Inflammatory bowel disease (IBD)
6. Human Diseases 6.3 Immune diseases hsa05330 Allograft rejection
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007050 cell cycle arrest
Biological Process GO:0016477 cell migration
Biological Process GO:0008283 cell population proliferation
Biological Process GO:0071346 cellular response to interferon-gamma
Biological Process GO:0071222 cellular response to lipopolysaccharide
Biological Process GO:0019221 cytokine-mediated signaling pathway
Biological Process GO:0050829 defense response to Gram-negative bacterium
Biological Process GO:0042832 defense response to protozoan
Biological Process GO:0051607 defense response to virus
Biological Process GO:0032609 interferon-gamma production
Biological Process GO:0035722 interleukin-12-mediated signaling pathway
Biological Process GO:0038155 interleukin-23-mediated signaling pathway
Biological Process GO:0030101 natural killer cell activation
Biological Process GO:0002323 natural killer cell activation involved in immune response
Biological Process GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis
Biological Process GO:0002862 negative regulation of inflammatory response to antigenic stimulus
Biological Process GO:0032693 negative regulation of interleukin-10 production
Biological Process GO:0032700 negative regulation of interleukin-17 production
Biological Process GO:0050709 negative regulation of protein secretion
Biological Process GO:0048662 negative regulation of smooth muscle cell proliferation
Biological Process GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway
Biological Process GO:0042104 positive regulation of activated T cell proliferation
Biological Process GO:0010536 positive regulation of activation of Janus kinase activity
Biological Process GO:0045785 positive regulation of cell adhesion
Biological Process GO:0002230 positive regulation of defense response to virus by host
Biological Process GO:0032725 positive regulation of granulocyte macrophage colony-stimulating factor production
Biological Process GO:0050729 positive regulation of inflammatory response
Biological Process GO:0032729 positive regulation of interferon-gamma production
Biological Process GO:0032733 positive regulation of interleukin-10 production
Biological Process GO:0032735 positive regulation of interleukin-12 production
Biological Process GO:0032740 positive regulation of interleukin-17 production
Biological Process GO:0050671 positive regulation of lymphocyte proliferation
Biological Process GO:0043382 positive regulation of memory T cell differentiation
Biological Process GO:0032946 positive regulation of mononuclear cell proliferation
Biological Process GO:0032816 positive regulation of natural killer cell activation
Biological Process GO:0002860 positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target
Biological Process GO:0032819 positive regulation of natural killer cell proliferation
Biological Process GO:1901224 positive regulation of NIK/NF-kappaB signaling
Biological Process GO:0051135 positive regulation of NK T cell activation
Biological Process GO:0051142 positive regulation of NK T cell proliferation
Biological Process GO:0045672 positive regulation of osteoclast differentiation
Biological Process GO:0034393 positive regulation of smooth muscle cell apoptotic process
Biological Process GO:0001916 positive regulation of T cell mediated cytotoxicity
Biological Process GO:0042102 positive regulation of T cell proliferation
Biological Process GO:2000330 positive regulation of T-helper 17 cell lineage commitment
Biological Process GO:2000318 positive regulation of T-helper 17 type immune response
Biological Process GO:0002827 positive regulation of T-helper 1 type immune response
Biological Process GO:0034105 positive regulation of tissue remodeling
Biological Process GO:0032760 positive regulation of tumor necrosis factor production
Biological Process GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein
Biological Process GO:0042035 regulation of cytokine biosynthetic process
Biological Process GO:0042509 regulation of tyrosine phosphorylation of STAT protein
Biological Process GO:0010224 response to UV-B
Biological Process GO:0019233 sensory perception of pain
Biological Process GO:0019953 sexual reproduction
Biological Process GO:0035744 T-helper 1 cell cytokine production
Biological Process GO:0042088 T-helper 1 type immune response
Biological Process GO:0042093 T-helper cell differentiation
molecular function GO:0005125 cytokine activity
molecular function GO:0019955 cytokine binding
molecular function GO:0004896 cytokine receptor activity
molecular function GO:0042802 identical protein binding
molecular function GO:0042164 interleukin-12 alpha subunit binding
molecular function GO:0005143 interleukin-12 receptor binding
molecular function GO:0044877 protein-containing complex binding
molecular function GO:0046982 protein heterodimerization activity
cellular component GO:0005829 cytosol
cellular component GO:0005788 endoplasmic reticulum lumen
cellular component GO:0009897 external side of plasma membrane
cellular component GO:0005576 extracellular region
cellular component GO:0005615 extracellular space
cellular component GO:0043514 interleukin-12 complex
cellular component GO:0070743 interleukin-23 complex
cellular component GO:0031906 late endosome lumen
cellular component GO:0043235 receptor complex
Reactome
Pathway Id Pathway Name
R-HSA-1280215 Cytokine Signaling in Immune system
R-HSA-1280215 Cytokine Signaling in Immune system
R-HSA-168256 Immune System
R-HSA-168256 Immune System
R-HSA-447115 Interleukin-12 family signaling
R-HSA-447115 Interleukin-12 family signaling
R-HSA-449147 Signaling by Interleukins
R-HSA-449147 Signaling by Interleukins
R-HSA-6783783 Interleukin-10 signaling
R-HSA-6785807 Interleukin-4 and Interleukin-13 signaling
R-HSA-9020591 Interleukin-12 signaling
R-HSA-9020591 Interleukin-12 signaling
R-HSA-9020933 Interleukin-23 signaling
R-HSA-9020933 Interleukin-23 signaling
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0000786 BXGD000010 Spontaneous abortion Female Urogenital Diseases and Pregnancy Complications
C0000822 BXGD000012 Abortion, Tubal Female Urogenital Diseases and Pregnancy Complications
C0001175 BXGD000029 Acquired Immunodeficiency Syndrome Infections; Immune System Diseases
C0001339 BXGD000041 Acute pancreatitis Digestive System Diseases
C0001418 BXGD000050 Adenocarcinoma Neoplasms
C0001973 BXGD000095 Alcoholic Intoxication, Chronic Chemically-Induced Disorders; Mental Disorders
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0002871 BXGD000132 Anemia Hemic and Lymphatic Diseases
C0003123 BXGD000178 Anorexia Pathological Conditions, Signs and Symptoms
C0003164 BXGD000185 Anthracosilicosis Respiratory Tract Diseases; Occupational Diseases
C0003862 BXGD000230 Arthralgia Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases
C0003864 BXGD000231 Arthritis Musculoskeletal Diseases
C0003872 BXGD000235 Arthritis, Psoriatic Skin and Connective Tissue Diseases; Musculoskeletal Diseases
C0003873 BXGD000236 Rheumatoid Arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0004096 BXGD000252 Asthma Respiratory Tract Diseases; Immune System Diseases
C0004364 BXGD000270 Autoimmune Diseases Immune System Diseases
C0004763 BXGD000289 Barrett Esophagus Digestive System Diseases; Neoplasms
C0004943 BXGD000297 Behcet Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Skin and Connective Tissue Diseases; Stomatognathic Diseases; Cardiovascular Diseases
C0006118 BXGD000372 Brain Neoplasms Neoplasms; Nervous System Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006309 BXGD000392 Brucellosis Infections
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007131 BXGD000441 Non-Small Cell Lung Carcinoma Neoplasms; Respiratory Tract Diseases
C0007194 BXGD000452 Hypertrophic Cardiomyopathy Cardiovascular Diseases
C0007570 BXGD000467 Celiac Disease Digestive System Diseases; Nutritional and Metabolic Diseases
C0007766 BXGD000478 Intracranial Aneurysm Nervous System Diseases; Cardiovascular Diseases
C0007847 BXGD000492 Malignant tumor of cervix Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0007930 BXGD000502 Chagas Cardiomyopathy Infections; Cardiovascular Diseases
C0008031 BXGD000511 Chest Pain Pathological Conditions, Signs and Symptoms
C0008312 BXGD000527 Primary biliary cirrhosis Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0009324 BXGD000597 Ulcerative Colitis Digestive System Diseases
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0009763 BXGD000628 Conjunctivitis Eye Diseases
C0010054 BXGD000647 Coronary Arteriosclerosis Cardiovascular Diseases
C0010068 BXGD000648 Coronary heart disease Cardiovascular Diseases
C0010346 BXGD000664 Crohn Disease Digestive System Diseases
C0010823 BXGD000690 Cytomegalovirus Infections Infections
C0011195 BXGD000702 Dejerine-Sottas Disease (disorder) Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0011265 BXGD000708 Presenile dementia Nervous System Diseases; Mental Disorders
C0011615 BXGD000738 Dermatitis, Atopic Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases; Immune System Diseases
C0011847 BXGD000749 Diabetes Endocrine System Diseases
C0011849 BXGD000751 Diabetes Mellitus Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011854 BXGD000753 Diabetes Mellitus, Insulin-Dependent Nutritional and Metabolic Diseases; Immune System Diseases; Endocrine System Diseases
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0012754 BXGD000788 Distemper Infections; Animal Diseases
C0013595 BXGD000858 Eczema Skin and Connective Tissue Diseases
C0014060 BXGD000882 Encephalitis, St. Louis Infections; Nervous System Diseases
C0014072 BXGD000888 Experimental Autoimmune Encephalomyelitis Immune System Diseases; Nervous System Diseases
C0014175 BXGD000904 Endometriosis Female Urogenital Diseases and Pregnancy Complications
C0014859 BXGD000961 Esophageal Neoplasms Digestive System Diseases; Neoplasms
C0014869 BXGD000966 Peptic Esophagitis Digestive System Diseases
C0015397 BXGD000983 Disorder of eye Eye Diseases
C0015672 BXGD001011 Fatigue Pathological Conditions, Signs and Symptoms
C0015967 BXGD001030 Fever Pathological Conditions, Signs and Symptoms
C0017086 BXGD001091 Gangrene Pathological Conditions, Signs and Symptoms
C0017638 BXGD001132 Glioma Neoplasms
C0018213 BXGD001187 Graves Disease Eye Diseases; Immune System Diseases; Endocrine System Diseases
C0018378 BXGD001190 Guillain-Barre Syndrome Immune System Diseases; Nervous System Diseases
C0019079 BXGD001278 Hemoptysis Pathological Conditions, Signs and Symptoms; Respiratory Tract Diseases
C0019100 BXGD001283 Severe Dengue Infections
C0019158 BXGD001293 Hepatitis Digestive System Diseases
C0019159 BXGD001294 Hepatitis A Digestive System Diseases; Infections
C0019163 BXGD001295 Hepatitis B Digestive System Diseases; Infections
C0019196 BXGD001301 Hepatitis C Digestive System Diseases; Infections
C0019372 BXGD001329 Herpesviridae Infections Infections
C0019829 BXGD001350 Hodgkin Disease Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0020179 BXGD001363 Huntington Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Mental Disorders
C0020458 BXGD001393 Hyperhidrosis disorder Skin and Connective Tissue Diseases
C0020538 BXGD001422 Hypertensive disease Cardiovascular Diseases
C0020546 BXGD001428 Hypertensive crisis Nervous System Diseases; Cardiovascular Diseases
C0020550 BXGD001429 Hyperthyroidism Endocrine System Diseases
C0020672 BXGD001461 Hypothermia, natural Pathological Conditions, Signs and Symptoms
C0021051 BXGD001475 Immunologic Deficiency Syndromes Immune System Diseases
C0021053 BXGD001476 Immune System Diseases Immune System Diseases
C0021368 BXGD001502 Inflammation Pathological Conditions, Signs and Symptoms
C0021390 BXGD001503 Inflammatory Bowel Diseases Digestive System Diseases
C0021831 BXGD001516 Intestinal Diseases Digestive System Diseases
C0022568 BXGD001552 Keratitis Eye Diseases
C0023343 BXGD001635 Leprosy Infections
C0023348 BXGD001636 Leprosy, Lepromatous Infections
C0023418 BXGD001642 leukemia Neoplasms
C0023449 BXGD001650 Acute lymphocytic leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023452 BXGD001651 Childhood Acute Lymphoblastic Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023892 BXGD001715 Biliary cirrhosis Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0023896 BXGD001718 Alcoholic Liver Diseases Digestive System Diseases; Chemically-Induced Disorders
C0023903 BXGD001720 Liver neoplasms Digestive System Diseases; Neoplasms
C0024115 BXGD001732 Lung diseases Respiratory Tract Diseases
C0024117 BXGD001734 Chronic Obstructive Airway Disease Respiratory Tract Diseases
C0024137 BXGD001737 Lupus Erythematosus, Cutaneous Skin and Connective Tissue Diseases
C0024141 BXGD001740 Lupus Erythematosus, Systemic Skin and Connective Tissue Diseases; Immune System Diseases
C0024299 BXGD001758 Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0024305 BXGD001763 Lymphoma, Non-Hodgkin Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0024530 BXGD001783 Malaria Infections
C0024534 BXGD001784 Malaria, Cerebral Infections; Nervous System Diseases
C0024535 BXGD001785 Malaria, Falciparum Infections
C0025007 BXGD001821 Measles Infections
C0025202 BXGD001832 melanoma Neoplasms
C0026272 BXGD001898 Mixed Connective Tissue Disease Skin and Connective Tissue Diseases
C0026691 BXGD001917 Mucocutaneous Lymph Node Syndrome Skin and Connective Tissue Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C0026769 BXGD001930 Multiple Sclerosis Immune System Diseases; Nervous System Diseases
C0026857 BXGD001943 Musculoskeletal Diseases Musculoskeletal Diseases
C0026896 BXGD001946 Myasthenia Gravis Neoplasms; Immune System Diseases; Nervous System Diseases
C0026918 BXGD001948 Mycobacterium Infections Infections
C0026919 BXGD001949 Mycobacterium Infections, Nontuberculous Infections
C0027051 BXGD001963 Myocardial Infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0027659 BXGD002012 Neoplasms, Experimental Neoplasms
C0027726 BXGD002030 Nephrotic Syndrome Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0027796 BXGD002037 Neuralgia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0029463 BXGD002160 Osteosarcoma Neoplasms
C0030246 BXGD002198 Pustulosis of Palms and Soles Skin and Connective Tissue Diseases
C0030409 BXGD002217 Paracoccidioidomycosis Infections
C0030524 BXGD002236 Paratuberculosis Infections; Animal Diseases
C0030920 BXGD002263 Peptic Ulcer Digestive System Diseases
C0031030 BXGD002272 Periapical Periodontitis Stomatognathic Diseases
C0031099 BXGD002282 Periodontitis Stomatognathic Diseases
C0033860 BXGD002438 Psoriasis Skin and Connective Tissue Diseases
C0034069 BXGD002458 Pulmonary Fibrosis Respiratory Tract Diseases
C0035309 BXGD002530 Retinal Diseases Eye Diseases
C0035455 BXGD002554 Rhinitis Infections; Respiratory Tract Diseases; Otorhinolaryngologic Diseases
C0035920 BXGD002570 Rubella Infections
C0036117 BXGD002577 Salmonella infections Infections
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0036572 BXGD002625 Seizures Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0037116 BXGD002666 Silicosis Respiratory Tract Diseases; Occupational Diseases
C0037299 BXGD002685 Skin Ulcer Skin and Connective Tissue Diseases
C0037822 BXGD002706 Speech Disorders Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0038013 BXGD002725 Ankylosing spondylitis Musculoskeletal Diseases
C0038356 BXGD002747 Stomach Neoplasms Digestive System Diseases; Neoplasms
C0038436 BXGD002755 Post-Traumatic Stress Disorder Mental Disorders
C0038454 BXGD002760 Cerebrovascular accident Nervous System Diseases; Cardiovascular Diseases
C0038522 BXGD002767 Subacute Sclerosing Panencephalitis Infections; Nervous System Diseases
C0039263 BXGD002805 Takayasu Arteritis Skin and Connective Tissue Diseases; Cardiovascular Diseases
C0040100 BXGD002840 Thymoma Neoplasms; Hemic and Lymphatic Diseases
C0040517 BXGD002872 Gilles de la Tourette syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Mental Disorders
C0041234 BXGD002901 Chagas Disease Infections
C0041296 BXGD002903 Tuberculosis Infections
C0041318 BXGD002909 Tuberculosis, Meningeal Infections; Nervous System Diseases
C0041327 BXGD002916 Tuberculosis, Pulmonary Infections; Respiratory Tract Diseases
C0042170 BXGD002969 Uveomeningoencephalitic Syndrome Eye Diseases; Immune System Diseases; Nervous System Diseases
C0042384 BXGD002979 Vasculitis Cardiovascular Diseases
C0042769 BXGD002999 Virus Diseases Infections
C0085082 BXGD003119 Fungemia Pathological Conditions, Signs and Symptoms; Infections
C0149793 BXGD003366 Amaurosis Fugax Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C0149931 BXGD003388 Migraine Disorders Nervous System Diseases
C0151313 BXGD003413 Sensory neuropathy Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0151332 BXGD003415 Active tuberculosis Infections
C0151786 BXGD003475 Muscle Weakness Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases
C0151811 BXGD003478 Subcutaneous nodule Neoplasms; Skin and Connective Tissue Diseases; Musculoskeletal Diseases
C0152018 BXGD003518 Esophageal carcinoma Digestive System Diseases; Neoplasms
C0153381 BXGD003626 Malignant neoplasm of mouth Neoplasms; Stomatognathic Diseases
C0155877 BXGD003830 Allergic asthma Respiratory Tract Diseases; Immune System Diseases
C0156147 BXGD003838 Crohn's disease of large bowel Digestive System Diseases
C0156344 BXGD003851 Endometriosis of ovary Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0162309 BXGD003934 Adrenoleukodystrophy Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases; Endocrine System Diseases
C0162871 BXGD003996 Aortic Aneurysm, Abdominal Cardiovascular Diseases
C0178468 BXGD004029 Autoimmune thyroid disease Immune System Diseases; Endocrine System Diseases
C0202117 BXGD004074 Low density lipoprotein cholesterol measurement
C0220597 BXGD004292 Adult Hodgkin Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0220641 BXGD004305 Lip and Oral Cavity Carcinoma Neoplasms; Stomatognathic Diseases
C0220644 BXGD004306 Childhood Hodgkin Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0231528 BXGD004496 Myalgia Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases
C0234428 BXGD004666 Disturbance of consciousness
C0238065 BXGD004869 Secondary Biliary Cholangitis Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0238301 BXGD004909 Cancer of Nasopharynx Neoplasms; Stomatognathic Diseases; Otorhinolaryngologic Diseases
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0242380 BXGD005158 Libman-Sacks Disease Skin and Connective Tissue Diseases; Immune System Diseases
C0242723 BXGD005193 Parasitemia Pathological Conditions, Signs and Symptoms; Infections
C0243026 BXGD005210 Sepsis Pathological Conditions, Signs and Symptoms; Infections
C0259783 BXGD005221 mixed gliomas Neoplasms
C0263361 BXGD005292 Psoriasis vulgaris Skin and Connective Tissue Diseases
C0264408 BXGD005387 Childhood asthma Respiratory Tract Diseases; Immune System Diseases
C0266929 BXGD005722 Chronic Periodontitis Stomatognathic Diseases
C0267380 BXGD005743 Crohn's disease of the ileum Digestive System Diseases
C0279671 BXGD006677 Cervical Squamous Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0302592 BXGD006851 Cervix carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0334634 BXGD007144 Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0339143 BXGD007226 Thyroid associated opthalmopathies Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Immune System Diseases; Endocrine System Diseases
C0345904 BXGD007745 Malignant neoplasm of liver Digestive System Diseases; Neoplasms
C0345967 BXGD007756 Malignant mesothelioma Neoplasms; Respiratory Tract Diseases
C0374997 BXGD007967 Helicobacter pylori (H. pylori) infection in conditions classified elsewhere and of unspecified site
C0403396 BXGD008276 Steroid-sensitive nephrotic syndrome Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0406317 BXGD008334 Chronic small plaque psoriasis Skin and Connective Tissue Diseases
C0428474 BXGD008631 Serum LDL cholesterol measurement
C0497169 BXGD009054 hiv-infection/aids Infections
C0497327 BXGD009061 Dementia Nervous System Diseases; Mental Disorders
C0546837 BXGD009343 Malignant neoplasm of esophagus Digestive System Diseases; Neoplasms
C0555198 BXGD009432 Malignant Glioma Neoplasms
C0585442 BXGD009593 Osteosarcoma of bone Neoplasms
C0677607 BXGD009721 Hashimoto Disease Endocrine System Diseases
C0677659 BXGD009724 Gastro-esophageal reflux disease with esophagitis Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0678202 BXGD009747 Regional enteritis Digestive System Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0740302 BXGD009975 5q-syndrome Pathological Conditions, Signs and Symptoms; Hemic and Lymphatic Diseases
C0745287 BXGD010125 infertility tubal factor
C0751606 BXGD010523 Adult Acute Lymphocytic Leukemia
C0751967 BXGD010657 Multiple Sclerosis, Relapsing-Remitting Immune System Diseases; Nervous System Diseases
C0856747 BXGD011112 Aneurysm of ascending aorta Respiratory Tract Diseases; Cardiovascular Diseases
C0858321 BXGD011175 Plasmodium vivax infection Infections
C0877445 BXGD011350 Candidemia Pathological Conditions, Signs and Symptoms; Infections
C0878544 BXGD011368 Cardiomyopathies Cardiovascular Diseases
C0917798 BXGD011409 Cerebral Ischemia Nervous System Diseases; Cardiovascular Diseases
C0949272 BXGD011573 IIeocolitis Digestive System Diseases
C1096155 BXGD011605 Macrophage Activation Syndrome Immune System Diseases
C1262477 BXGD011882 Weight decreased Pathological Conditions, Signs and Symptoms
C1282241 BXGD012142 Sterile keratitis Eye Diseases
C1292779 BXGD012238 Myelodysplastic Syndrome with Isolated del(5q) Hemic and Lymphatic Diseases
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C1332986 BXGD012574 Childhood Osteosarcoma Neoplasms
C1519176 BXGD013232 Salivary Gland Pleomorphic Adenoma Neoplasms; Stomatognathic Diseases
C1619738 BXGD013464 Immune Reconstitution Inflammatory Syndrome Immune System Diseases
C1719495 BXGD013656 Aggressive periodontitis, generalized Stomatognathic Diseases
C1802398 BXGD013758 Chromosome 5, trisomy 5q Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C1827849 BXGD013780 IgE-mediated allergic asthma Immune System Diseases
C1837388 BXGD014225 Abnormal pattern of respiration
C1848296 BXGD014918 DOSAGE-SENSITIVE SEX REVERSAL Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C1853829 BXGD015362 Arthropathy, Erosive Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases; Musculoskeletal Diseases
C1956346 BXGD016627 Coronary Artery Disease Cardiovascular Diseases
C1962966 BXGD016678 Retinopathy, CTCAE
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2363741 BXGD017100 HIV-1 infection
C2607914 BXGD017148 Allergic rhinitis (disorder) Respiratory Tract Diseases; Immune System Diseases; Otorhinolaryngologic Diseases
C2747816 BXGD017577 Complicated malaria Infections
C2895206 BXGD017852 Autoimmune disease (systemic) NOS
C2939419 BXGD018178 Secondary Neoplasm Pathological Conditions, Signs and Symptoms; Neoplasms
C2973725 BXGD018205 Pulmonary arterial hypertension Respiratory Tract Diseases; Cardiovascular Diseases
C3152231 BXGD018463 Gastrointestinal infarctions
C3164445 BXGD018529 Abnormality of aortic valve
C3203102 BXGD018555 Idiopathic pulmonary arterial hypertension Respiratory Tract Diseases
C3249881 BXGD018583 Infection - suppurative Pathological Conditions, Signs and Symptoms; Infections
C3489393 BXGD018928 Hiatal Hernia Pathological Conditions, Signs and Symptoms
C3714514 BXGD019409 Infection Infections
C3830362 BXGD019751 Early Pregnancy Loss Female Urogenital Diseases and Pregnancy Complications
C3840565 BXGD019797 Autoimmune thyroid disease (AITD)
C3874381 BXGD019865 Childhood nephrotic syndrome Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C3887645 BXGD019910 Job Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Immune System Diseases; Hemic and Lymphatic Diseases
C3887654 BXGD019912 POLYARTERITIS NODOSA, CHILDHOOD-ONSET Skin and Connective Tissue Diseases; Cardiovascular Diseases
C4013948 BXGD020134 IMMUNODEFICIENCY 29
C4020969 BXGD020517 Inflammatory abnormality of the eye
C4021662 BXGD020726 Abnormal endocardium morphology Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C4048328 BXGD021903 cervical cancer Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C4290046 BXGD022507 trachomatis
C4551595 BXGD023367 Biliary Cirrhosis, Primary, 1 Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C4552766 BXGD023523 Miscarriage Female Urogenital Diseases and Pregnancy Complications
C4721507 BXGD023747 Alveolitis, Fibrosing Respiratory Tract Diseases
C4722085 BXGD023788 Malignant neoplasm of colon and/or rectum
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002591 Potassium 39.1
BXGC0003705 Chloride 35.45
BXGC0018397 beta-1,4-mannan 180.06
BXGC0030612 tetraethylene glycol 194.12
BXGC0050194 alpha-D-Mannose 180.06
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein