Showing entry for Nitric oxide synthase, endothelial


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT009351
Protein NameNitric oxide synthase, endothelial
Uniport IdP29473
GeneNOS3
Gene Id
DomainFAD_binding_1; Flavodoxin_1; NAD_binding_1; NO_synthase
Pfam PF00667   PF00258   PF00175   PF02898  
OrganismBos taurus (Bovine)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006527 arginine catabolic process
Biological Process GO:0007596 blood coagulation
Biological Process GO:0071499 cellular response to laminar fluid shear stress
Biological Process GO:0007005 mitochondrion organization
Biological Process GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
Biological Process GO:1903038 negative regulation of leukocyte cell-cell adhesion
Biological Process GO:0006809 nitric oxide biosynthetic process
Biological Process GO:0031284 positive regulation of guanylate cyclase activity
molecular function GO:0005516 calmodulin binding
molecular function GO:0050660 flavin adenine dinucleotide binding
molecular function GO:0010181 FMN binding
molecular function GO:0020037 heme binding
molecular function GO:0046872 metal ion binding
molecular function GO:0050661 NADP binding
molecular function GO:0004517 nitric-oxide synthase activity
cellular component GO:0005901 caveola
cellular component GO:0005856 cytoskeleton
cellular component GO:0005794 Golgi apparatus
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000245 NG,NG-Dimethyl-L-arginine 202.25
BXGC0000247 L-Targinine 188.23
BXGC0000436 Glycerol 92.09
BXGC0001630 Arginine 174.2
BXGC0002690 alpha-Catechin 290.27
BXGC0003705 Chloride 35.45
BXGC0005750 2,6-Di-tert-butyl-4-methylphenol 220.35
BXGC0008676 Haem 616.49
BXGC0023600 4a-carbinolamine tetrahydrobiopterin 239.1
BXGC0029829 Epicatechin Pentaacetate 500.13
BXGC0037242 Homoarginine 188.13
BXGC0044637 1400W 177.13
BXGC0048267 Canavanine 176.09
BXGC0049200 Arginine 175.12
BXGC0049447 acetate 59.01
BXGC0051982 Mannitol 182.08
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein