Showing entry for Leiomodin-1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT009361
Protein NameLeiomodin-1
Uniport IdP29536
GeneLMOD1
Gene Id25802
DomainTropomodulin; WH2
Pfam PF03250   PF02205  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007015 actin filament organization
Biological Process GO:0045010 actin nucleation
Biological Process GO:0006936 muscle contraction
Biological Process GO:0030239 myofibril assembly
Biological Process GO:0051694 pointed-end actin filament capping
Biological Process GO:0030838 positive regulation of actin filament polymerization
molecular function GO:0003779 actin binding
molecular function GO:0005523 tropomyosin binding
cellular component GO:0005884 actin filament
cellular component GO:0005856 cytoskeleton
cellular component GO:0005829 cytosol
cellular component GO:0016020 membrane
cellular component GO:0030016 myofibril
cellular component GO:0030017 sarcomere
cellular component GO:0005865 striated muscle thin filament
Reactome
Pathway Id Pathway Name
R-HSA-397014 Muscle contraction
R-HSA-445355 Smooth Muscle Contraction
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0000731 BXGD000002 Abdomen distended Digestive System Diseases
C0003850 BXGD000225 Arteriosclerosis Cardiovascular Diseases
C0004153 BXGD000260 Atherosclerosis Cardiovascular Diseases
C0007766 BXGD000478 Intracranial Aneurysm Nervous System Diseases; Cardiovascular Diseases
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0010054 BXGD000647 Coronary Arteriosclerosis Cardiovascular Diseases
C0010068 BXGD000648 Coronary heart disease Cardiovascular Diseases
C0010417 BXGD000670 Cryptorchidism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Male Urogenital Diseases; Endocrine System Diseases
C0011854 BXGD000753 Diabetes Mellitus, Insulin-Dependent Nutritional and Metabolic Diseases; Immune System Diseases; Endocrine System Diseases
C0014175 BXGD000904 Endometriosis Female Urogenital Diseases and Pregnancy Complications
C0018213 BXGD001187 Graves Disease Eye Diseases; Immune System Diseases; Endocrine System Diseases
C0018809 BXGD001230 Heart Neoplasm Neoplasms; Cardiovascular Diseases
C0020224 BXGD001366 Polyhydramnios Female Urogenital Diseases and Pregnancy Complications
C0020550 BXGD001429 Hyperthyroidism Endocrine System Diseases
C0023269 BXGD001627 leiomyosarcoma Neoplasms
C0027498 BXGD001994 Nausea and vomiting Pathological Conditions, Signs and Symptoms
C0036202 BXGD002581 Sarcoidosis Hemic and Lymphatic Diseases
C0038868 BXGD002781 Progressive supranuclear palsy Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C0042781 BXGD003000 Visceral Myopathy Digestive System Diseases
C0149632 BXGD003335 Abnormality of the bladder Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0202117 BXGD004074 Low density lipoprotein cholesterol measurement
C0221210 BXGD004406 Congenital malrotation of intestine Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases
C0232475 BXGD004545 Decreased peristalsis
C0243026 BXGD005210 Sepsis Pathological Conditions, Signs and Symptoms; Infections
C0266200 BXGD005630 Microcolon Digestive System Diseases
C0269102 BXGD006053 Endometrioma Female Urogenital Diseases and Pregnancy Complications
C0278607 BXGD006548 Adult Leiomyosarcoma Neoplasms
C0279626 BXGD006657 Squamous cell carcinoma of esophagus Digestive System Diseases; Neoplasms
C0279986 BXGD006705 Childhood Leiomyosarcoma Neoplasms
C0424574 BXGD008534 Duration of sleep
C0425782 BXGD008551 Breast size
C0428474 BXGD008631 Serum LDL cholesterol measurement
C0521620 BXGD009150 Dilatation of ureter Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0525045 BXGD009255 Mood Disorders Mental Disorders
C0795690 BXGD010728 Congenital omphalocele Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C1269683 BXGD012001 Major Depressive Disorder Mental Disorders
C1305855 BXGD012348 Body mass index
C1306503 BXGD012363 Congenital exomphalos Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C1608393 BXGD013433 Megacystis microcolon intestinal hypoperistalsis syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases
C1855311 BXGD015486 Megacystis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications
C1857276 BXGD015688 Trichohepatoenteric Syndrome Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Skin and Connective Tissue Diseases
C1858430 BXGD015792 Death in infancy
C1956346 BXGD016627 Coronary Artery Disease Cardiovascular Diseases
C2931117 BXGD017960 Fetal megacystis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications
C3658353 BXGD019261 Nodding Syndrome Nervous System Diseases
C3714581 BXGD019415 Multicystic Dysplastic Kidney Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C3887938 BXGD019929 Deuteranomaly Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C3888088 BXGD019947 SMITH-MCCORT DYSPLASIA 1 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C4049938 BXGD021956 Physical Activity Measurement
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0003705 Chloride 35.45
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein