Showing entry for Calsequestrin-1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT009537
Protein NameCalsequestrin-1
Uniport IdP31415
GeneCASQ1
Gene Id844
DomainCalsequestrin
Pfam PF01216  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
3. Environmental Information Processing 3.2 Signal transduction hsa04020 Calcium signaling pathway
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007029 endoplasmic reticulum organization
Biological Process GO:0034220 ion transmembrane transport
Biological Process GO:0051281 positive regulation of release of sequestered calcium ion into cytosol
Biological Process GO:1901341 positive regulation of store-operated calcium channel activity
Biological Process GO:0051258 protein polymerization
Biological Process GO:1903779 regulation of cardiac conduction
Biological Process GO:0051279 regulation of release of sequestered calcium ion into cytosol
Biological Process GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion
Biological Process GO:2001256 regulation of store-operated calcium entry
Biological Process GO:0014894 response to denervation involved in regulation of muscle adaptation
Biological Process GO:0009408 response to heat
Biological Process GO:0010033 response to organic substance
Biological Process GO:0045214 sarcomere organization
Biological Process GO:0007519 skeletal muscle tissue development
molecular function GO:0005509 calcium ion binding
molecular function GO:0042802 identical protein binding
cellular component GO:0005783 endoplasmic reticulum
cellular component GO:0005794 Golgi apparatus
cellular component GO:0005759 mitochondrial matrix
cellular component GO:0005739 mitochondrion
cellular component GO:0016529 sarcoplasmic reticulum
cellular component GO:0033018 sarcoplasmic reticulum lumen
cellular component GO:0033017 sarcoplasmic reticulum membrane
cellular component GO:0005790 smooth endoplasmic reticulum
cellular component GO:0014804 terminal cisterna lumen
cellular component GO:0030315 T-tubule
cellular component GO:0030018 Z disc
Reactome
Pathway Id Pathway Name
R-HSA-2672351 Stimuli-sensing channels
R-HSA-382551 Transport of small molecules
R-HSA-397014 Muscle contraction
R-HSA-5576891 Cardiac conduction
R-HSA-5578775 Ion homeostasis
R-HSA-983712 Ion channel transport
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0004364 BXGD000270 Autoimmune Diseases Immune System Diseases
C0009917 BXGD000635 Contracture Musculoskeletal Diseases
C0011847 BXGD000749 Diabetes Endocrine System Diseases
C0011849 BXGD000751 Diabetes Mellitus Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011853 BXGD000752 Diabetes Mellitus, Experimental Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0013264 BXGD000808 Muscular Dystrophy, Duchenne Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C0015967 BXGD001030 Fever Pathological Conditions, Signs and Symptoms
C0024591 BXGD001789 Malignant hyperpyrexia due to anesthesia Pathological Conditions, Signs and Symptoms
C0026848 BXGD001941 Myopathy Musculoskeletal Diseases; Nervous System Diseases
C0027121 BXGD001973 Myositis Musculoskeletal Diseases; Nervous System Diseases
C0029182 BXGD002121 orbit (eye disorders) Eye Diseases
C0037763 BXGD002699 Spasm Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0038454 BXGD002760 Cerebrovascular accident Nervous System Diseases; Cardiovascular Diseases
C0154723 BXGD003737 Migraine with Aura Nervous System Diseases
C0221629 BXGD004467 Proximal muscle weakness Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases
C0231528 BXGD004496 Myalgia Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases
C0241005 BXGD005072 Creatine phosphokinase serum increased
C0271650 BXGD006227 Impaired glucose tolerance Nutritional and Metabolic Diseases
C0338480 BXGD007186 Common Migraine Nervous System Diseases
C0339143 BXGD007226 Thyroid associated opthalmopathies Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Immune System Diseases; Endocrine System Diseases
C0410207 BXGD008419 Tubular Aggregate Myopathy Musculoskeletal Diseases; Nervous System Diseases
C1837098 BXGD014198 Easy fatigability
C1839615 BXGD014390 X-linked myopathy with excessive autophagy Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C1842170 BXGD014503 Centrally nucleated skeletal muscle fibers
C1843700 BXGD014604 Increased variability in muscle fiber diameter
C1861451 BXGD016047 Stormorken Syndrome Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Skin and Connective Tissue Diseases; Nervous System Diseases; Mental Disorders; Hemic and Lymphatic Diseases
C1864580 BXGD016235 Type 2 muscle fiber atrophy
C2931230 BXGD017985 Vacuolar myopathy Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Musculoskeletal Diseases; Nervous System Diseases
C4011726 BXGD020114 MYOPATHY, TUBULAR AGGREGATE, 1 Musculoskeletal Diseases; Nervous System Diseases
C4015624 BXGD020215 MYOPATHY, VACUOLAR, WITH CASQ1 AGGREGATES
C4021024 BXGD020522 Muscle fiber tubular inclusions
C4021726 BXGD020735 EMG: myopathic abnormalities Musculoskeletal Diseases; Nervous System Diseases
C4022583 BXGD020924 Fatiguable weakness of proximal limb muscles
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002586 Calcium 40.08
BXGC0037687 (4S)-2-methylpentane-2,4-diol 118.1
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein