Showing entry for Tyrosine-protein kinase CSK



                       
General Target Information
BXGT IdBXGT009649
Protein NameTyrosine-protein kinase CSK
Uniport IdP32577
GeneCsk
Gene Id315707
DomainPkinase_Tyr; SH2; SH3_1
Pfam PF07714   PF00017   PF00018  
OrganismRattus norvegicus (Rat)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0002250 adaptive immune response
Biological Process GO:0034332 adherens junction organization
Biological Process GO:0007420 brain development
Biological Process GO:0071375 cellular response to peptide hormone stimulus
Biological Process GO:0045779 negative regulation of bone resorption
Biological Process GO:0008285 negative regulation of cell population proliferation
Biological Process GO:0070373 negative regulation of ERK1 and ERK2 cascade
Biological Process GO:0042997 negative regulation of Golgi to plasma membrane protein transport
Biological Process GO:0032715 negative regulation of interleukin-6 production
Biological Process GO:0033673 negative regulation of kinase activity
Biological Process GO:0010989 negative regulation of low-density lipoprotein particle clearance
Biological Process GO:0050765 negative regulation of phagocytosis
Biological Process GO:0048709 oligodendrocyte differentiation
Biological Process GO:0043406 positive regulation of MAP kinase activity
Biological Process GO:0046777 protein autophosphorylation
Biological Process GO:0006468 protein phosphorylation
Biological Process GO:0060368 regulation of Fc receptor mediated stimulatory signaling pathway
molecular function GO:0005524 ATP binding
molecular function GO:0042802 identical protein binding
molecular function GO:0046872 metal ion binding
molecular function GO:0004715 non-membrane spanning protein tyrosine kinase activity
molecular function GO:0070064 proline-rich region binding
molecular function GO:0034236 protein kinase A catalytic subunit binding
molecular function GO:0019903 protein phosphatase binding
molecular function GO:0004713 protein tyrosine kinase activity
cellular component GO:0005911 cell-cell junction
cellular component GO:0005737 cytoplasm
cellular component GO:0045121 membrane raft
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0006193 Ellagic acid 302.19
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein