protein

Showing entry for 72 kDa type IV collagenase

General Target Information
BXGT Id	BXGT009724
Protein Name	72 kDa type IV collagenase
Uniport Id	P33436
Gene	Mmp2
Gene Id	81686
Domain	fn2; Hemopexin; Peptidase_M10; PG_binding_1
Pfam	PF00040 PF00045 PF00413 PF01471
Organism	Rattus norvegicus (Rat)

Target protein affiliated biological pathways

KEGG

Class	Subclass	KEGG Id	Pathway Name

Gene Ontology

GO Type	GO Id	Gene Ontology
Biological Process	GO:0007568	aging
Biological Process	GO:0001525	angiogenesis
Biological Process	GO:0001955	blood vessel maturation
Biological Process	GO:0060346	bone trabecula formation
Biological Process	GO:0016477	cell migration
Biological Process	GO:0071230	cellular response to amino acid stimulus
Biological Process	GO:0071345	cellular response to cytokine stimulus
Biological Process	GO:0071392	cellular response to estradiol stimulus
Biological Process	GO:0071498	cellular response to fluid shear stress
Biological Process	GO:0071347	cellular response to interleukin-1
Biological Process	GO:0034614	cellular response to reactive oxygen species
Biological Process	GO:0030574	collagen catabolic process
Biological Process	GO:0007566	embryo implantation
Biological Process	GO:0035987	endodermal cell differentiation
Biological Process	GO:0030198	extracellular matrix organization
Biological Process	GO:0060325	face morphogenesis
Biological Process	GO:0007565	female pregnancy
Biological Process	GO:0007507	heart development
Biological Process	GO:0001957	intramembranous ossification
Biological Process	GO:0001553	luteinization
Biological Process	GO:0007162	negative regulation of cell adhesion
Biological Process	GO:0045906	negative regulation of vasoconstriction
Biological Process	GO:0001541	ovarian follicle development
Biological Process	GO:0001542	ovulation from ovarian follicle
Biological Process	GO:0007567	parturition
Biological Process	GO:0014012	peripheral nervous system axon regeneration
Biological Process	GO:0043065	positive regulation of apoptotic process
Biological Process	GO:0030335	positive regulation of cell migration
Biological Process	GO:0045089	positive regulation of innate immune response
Biological Process	GO:0048661	positive regulation of smooth muscle cell proliferation
Biological Process	GO:1904707	positive regulation of vascular associated smooth muscle cell proliferation
Biological Process	GO:0060740	prostate gland epithelium morphogenesis
Biological Process	GO:0006508	proteolysis
Biological Process	GO:0014823	response to activity
Biological Process	GO:1904645	response to amyloid-beta
Biological Process	GO:0034097	response to cytokine
Biological Process	GO:0042493	response to drug
Biological Process	GO:0051602	response to electrical stimulus
Biological Process	GO:0043627	response to estrogen
Biological Process	GO:0042542	response to hydrogen peroxide
Biological Process	GO:0055093	response to hyperoxia
Biological Process	GO:0001666	response to hypoxia
Biological Process	GO:0009612	response to mechanical stimulus
Biological Process	GO:0035094	response to nicotine
Biological Process	GO:0006979	response to oxidative stress
Biological Process	GO:0009314	response to radiation
Biological Process	GO:0032526	response to retinoic acid
Biological Process	GO:0048705	skeletal system morphogenesis
Biological Process	GO:0048771	tissue remodeling
molecular function	GO:0004175	endopeptidase activity
molecular function	GO:0001968	fibronectin binding
molecular function	GO:0004222	metalloendopeptidase activity
molecular function	GO:0008237	metallopeptidase activity
molecular function	GO:0008233	peptidase activity
molecular function	GO:0004252	serine-type endopeptidase activity
molecular function	GO:0008270	zinc ion binding
cellular component	GO:0005737	cytoplasm
cellular component	GO:0031012	extracellular matrix
cellular component	GO:0005615	extracellular space
cellular component	GO:0005739	mitochondrion
cellular component	GO:0005634	nucleus
cellular component	GO:0005886	plasma membrane
cellular component	GO:0030017	sarcomere

Reactome

Pathway Id	Pathway Name

Target protein-related diseases

Disease

CUI Id	BXGD Id	Disease Name	Disease Class

Target protein-related compounds

Compounds

BXGC Id	Compound Name	Strcuture	Molecular Weight
BXGC0018442	Lithospermic Acid		538.11
BXGC0021834	Methyl Rosmarinate		374.1
BXGC0026028	Clinopodic acid A		344.09
BXGC0048313	Rosmarinic Acid		360.08

The target protein-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compound^{? Number of compound in food, higher numbers indicate the food are more associated with the protein}