Showing entry for Ecdysone receptor


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT009746
Protein NameEcdysone receptor
Uniport IdP34021
GeneEcR
Gene Id35540
DomainHormone_recep; zf-C4
Pfam PF00104   PF00105  
OrganismDrosophila melanogaster (Fruit fly)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006914 autophagy
Biological Process GO:0007298 border follicle cell migration
Biological Process GO:0048738 cardiac muscle tissue development
Biological Process GO:0010002 cardioblast differentiation
Biological Process GO:0007155 cell adhesion
Biological Process GO:0030154 cell differentiation
Biological Process GO:0040003 chitin-based cuticle development
Biological Process GO:0008362 chitin-based embryonic cuticle biosynthetic process
Biological Process GO:0042632 cholesterol homeostasis
Biological Process GO:0048813 dendrite morphogenesis
Biological Process GO:0008340 determination of adult lifespan
Biological Process GO:0035053 dorsal vessel heart proper cell fate commitment
Biological Process GO:0018990 ecdysis, chitin-based cuticle
Biological Process GO:0035072 ecdysone-mediated induction of salivary gland cell autophagic cell death
Biological Process GO:0035076 ecdysone receptor-mediated signaling pathway
Biological Process GO:0008544 epidermis development
Biological Process GO:0007390 germ-band shortening
Biological Process GO:0007281 germ cell development
Biological Process GO:0035188 hatching
Biological Process GO:0008258 head involution
Biological Process GO:0007488 histoblast morphogenesis
Biological Process GO:0007476 imaginal disc-derived wing morphogenesis
Biological Process GO:0035193 larval central nervous system remodeling
Biological Process GO:0002164 larval development
Biological Process GO:0035180 larval wandering behavior
Biological Process GO:0055088 lipid homeostasis
Biological Process GO:0006629 lipid metabolic process
Biological Process GO:0007616 long-term memory
Biological Process GO:0007443 Malpighian tubule morphogenesis
Biological Process GO:0007552 metamorphosis
Biological Process GO:0016319 mushroom body development
Biological Process GO:0045892 negative regulation of transcription, DNA-templated
Biological Process GO:0000122 negative regulation of transcription by RNA polymerase II
Biological Process GO:0016322 neuron remodeling
Biological Process GO:0048477 oogenesis
Biological Process GO:0007422 peripheral nervous system development
Biological Process GO:0006911 phagocytosis, engulfment
Biological Process GO:0043065 positive regulation of apoptotic process
Biological Process GO:0045938 positive regulation of circadian sleep/wake cycle, sleep
Biological Process GO:1904801 positive regulation of neuron remodeling
Biological Process GO:0045893 positive regulation of transcription, DNA-templated
Biological Process GO:0045944 positive regulation of transcription by RNA polymerase II
Biological Process GO:0035073 pupariation
Biological Process GO:0010506 regulation of autophagy
Biological Process GO:0043457 regulation of cellular respiration
Biological Process GO:0040034 regulation of development, heterochronic
Biological Process GO:0035206 regulation of hemocyte proliferation
Biological Process GO:0035297 regulation of Malpighian tubule diameter
Biological Process GO:1904799 regulation of neuron remodeling
Biological Process GO:0007468 regulation of rhodopsin gene expression
Biological Process GO:0006357 regulation of transcription by RNA polymerase II
Biological Process GO:0042220 response to cocaine
Biological Process GO:0035075 response to ecdysone
Biological Process GO:0035071 salivary gland cell autophagic cell death
Biological Process GO:0007291 sperm individualization
molecular function GO:0001046 core promoter sequence-specific DNA binding
molecular function GO:0003677 DNA binding
molecular function GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
molecular function GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
molecular function GO:0035100 ecdysone binding
molecular function GO:0004879 nuclear receptor activity
molecular function GO:0046982 protein heterodimerization activity
molecular function GO:0042803 protein homodimerization activity
molecular function GO:0070491 repressing transcription factor binding
molecular function GO:0001225 RNA polymerase II transcription coactivator binding
molecular function GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
molecular function GO:0038023 signaling receptor activity
molecular function GO:0005102 signaling receptor binding
molecular function GO:0005496 steroid binding
molecular function GO:0008134 transcription factor binding
molecular function GO:0000976 transcription regulatory region sequence-specific DNA binding
molecular function GO:0008270 zinc ion binding
cellular component GO:0008232 activator ecdysone receptor complex
cellular component GO:0005737 cytoplasm
cellular component GO:0030425 dendrite
cellular component GO:0008230 ecdysone receptor holocomplex
cellular component GO:0005634 nucleus
cellular component GO:0005700 polytene chromosome
cellular component GO:0008231 repressor ecdysone receptor complex
cellular component GO:0090575 RNA polymerase II transcription regulator complex
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0003905 Ecdysone 464.63
BXGC0022186 Ponasterone A 464.31
BXGC0026446 Inokosterone 480.31
BXGC0028273 Makisterone A 494.32
BXGC0034674 20-Hydroxyecdysone 480.31
BXGC0046797 Cyasterone 520.3
BXGC0046850 Inokosterone 480.31
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein