Showing entry for 5-hydroxytryptamine receptor 2C


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT009776
Protein Name5-hydroxytryptamine receptor 2C
Uniport IdP34968
GeneHtr2c
Gene Id15560
Domain7tm_1
Pfam PF00001  
OrganismMus musculus (Mouse)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0001662 behavioral fear response
Biological Process GO:0035095 behavioral response to nicotine
Biological Process GO:0006874 cellular calcium ion homeostasis
Biological Process GO:0019934 cGMP-mediated signaling
Biological Process GO:0007268 chemical synaptic transmission
Biological Process GO:0007631 feeding behavior
Biological Process GO:0007187 G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
Biological Process GO:0048016 inositol phosphate-mediated signaling
Biological Process GO:0007626 locomotory behavior
Biological Process GO:0045963 negative regulation of dopamine metabolic process
Biological Process GO:0040013 negative regulation of locomotion
Biological Process GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway
Biological Process GO:0007208 phospholipase C-activating serotonin receptor signaling pathway
Biological Process GO:0031583 phospholipase D-activating G protein-coupled receptor signaling pathway
Biological Process GO:0014057 positive regulation of acetylcholine secretion, neurotransmission
Biological Process GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway
Biological Process GO:0070374 positive regulation of ERK1 and ERK2 cascade
Biological Process GO:0045600 positive regulation of fat cell differentiation
Biological Process GO:0014054 positive regulation of gamma-aminobutyric acid secretion
Biological Process GO:0010513 positive regulation of phosphatidylinositol biosynthetic process
Biological Process GO:0045907 positive regulation of vasoconstriction
Biological Process GO:0032098 regulation of appetite
Biological Process GO:0043397 regulation of corticotropin-releasing hormone secretion
Biological Process GO:0031644 regulation of nervous system process
Biological Process GO:0051930 regulation of sensory perception of pain
Biological Process GO:0051209 release of sequestered calcium ion into cytosol
Biological Process GO:0042493 response to drug
Biological Process GO:0007210 serotonin receptor signaling pathway
molecular function GO:0071886 1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding
molecular function GO:0008144 drug binding
molecular function GO:0004930 G protein-coupled receptor activity
molecular function GO:0004993 G protein-coupled serotonin receptor activity
molecular function GO:0001587 Gq/11-coupled serotonin receptor activity
molecular function GO:0042802 identical protein binding
molecular function GO:0030594 neurotransmitter receptor activity
molecular function GO:0051378 serotonin binding
cellular component GO:0009986 cell surface
cellular component GO:0030425 dendrite
cellular component GO:0009897 external side of plasma membrane
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0005886 plasma membrane
cellular component GO:0045202 synapse
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0005867 Serotonin 176.22
BXGC0046755 Yohimbine 354.19
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein