Showing entry for Inward rectifier potassium channel 2


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT009848
Protein NameInward rectifier potassium channel 2
Uniport IdP35561
GeneKcnj2
Gene Id16518
DomainIRK; IRK_C; IRK_N
Pfam PF01007   PF17655   PF08466  
OrganismMus musculus (Mouse)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0086001 cardiac muscle cell action potential
Biological Process GO:0086002 cardiac muscle cell action potential involved in contraction
Biological Process GO:0071260 cellular response to mechanical stimulus
Biological Process GO:0015693 magnesium ion transport
Biological Process GO:0086011 membrane repolarization during action potential
Biological Process GO:0086013 membrane repolarization during cardiac muscle cell action potential
Biological Process GO:1901381 positive regulation of potassium ion transmembrane transport
Biological Process GO:1990573 potassium ion import across plasma membrane
Biological Process GO:0071805 potassium ion transmembrane transport
Biological Process GO:0006813 potassium ion transport
Biological Process GO:0051289 protein homotetramerization
Biological Process GO:0086004 regulation of cardiac muscle cell contraction
Biological Process GO:0086091 regulation of heart rate by cardiac conduction
Biological Process GO:0034765 regulation of ion transmembrane transport
Biological Process GO:0060306 regulation of membrane repolarization
Biological Process GO:0014861 regulation of skeletal muscle contraction via regulation of action potential
Biological Process GO:0055119 relaxation of cardiac muscle
Biological Process GO:0090076 relaxation of skeletal muscle
molecular function GO:0042802 identical protein binding
molecular function GO:0005242 inward rectifier potassium channel activity
molecular function GO:0005546 phosphatidylinositol-4,5-bisphosphate binding
molecular function GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization
cellular component GO:0030425 dendrite
cellular component GO:0043197 dendritic spine
cellular component GO:0005794 Golgi apparatus
cellular component GO:0014704 intercalated disc
cellular component GO:0031224 intrinsic component of membrane
cellular component GO:0043025 neuronal cell body
cellular component GO:0005886 plasma membrane
cellular component GO:0005791 rough endoplasmic reticulum
cellular component GO:0005790 smooth endoplasmic reticulum
cellular component GO:0030315 T-tubule
cellular component GO:0008076 voltage-gated potassium channel complex
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002591 Potassium 39.1
BXGC0037687 (4S)-2-methylpentane-2,4-diol 118.1
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein