Showing entry for Thioredoxin-dependent peroxide reductase, mitochondrial


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT009860
Protein NameThioredoxin-dependent peroxide reductase, mitochondrial
Uniport IdP35705
GenePRDX3
Gene Id281998
Domain1-cysPrx_C; AhpC-TSA
Pfam PF10417   PF00578  
OrganismBos taurus (Bovine)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0045454 cell redox homeostasis
Biological Process GO:0034599 cellular response to oxidative stress
Biological Process GO:0034614 cellular response to reactive oxygen species
Biological Process GO:0042744 hydrogen peroxide catabolic process
Biological Process GO:0001893 maternal placenta development
Biological Process GO:0007005 mitochondrion organization
Biological Process GO:0030099 myeloid cell differentiation
Biological Process GO:0033673 negative regulation of kinase activity
Biological Process GO:0018171 peptidyl-cysteine oxidation
Biological Process GO:0008284 positive regulation of cell population proliferation
Biological Process GO:0051092 positive regulation of NF-kappaB transcription factor activity
Biological Process GO:0051881 regulation of mitochondrial membrane potential
Biological Process GO:0042542 response to hydrogen peroxide
Biological Process GO:0032496 response to lipopolysaccharide
molecular function GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process
molecular function GO:0042802 identical protein binding
molecular function GO:0008022 protein C-terminus binding
molecular function GO:0019901 protein kinase binding
molecular function GO:0008379 thioredoxin peroxidase activity
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0005769 early endosome
cellular component GO:0005759 mitochondrial matrix
cellular component GO:0005739 mitochondrion
cellular component GO:0032991 protein-containing complex
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0006198 Citric acid 192.12
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein