protein

Showing entry for Tyrosine-protein kinase BTK

General Target Information
BXGT Id	BXGT009889
Protein Name	Tyrosine-protein kinase BTK
Uniport Id	P35991
Gene	Btk
Gene Id	12229
Domain	BTK; PH; Pkinase_Tyr; SH2; SH3_1
Pfam	PF00779 PF00169 PF07714 PF00017 PF00018
Organism	Mus musculus (Mouse)

Target protein affiliated biological pathways

KEGG

Class	Subclass	KEGG Id	Pathway Name

Gene Ontology

GO Type	GO Id	Gene Ontology
Biological Process	GO:0006915	apoptotic process
Biological Process	GO:0002344	B cell affinity maturation
Biological Process	GO:0048469	cell maturation
Biological Process	GO:0098761	cellular response to interleukin-7
Biological Process	GO:0071226	cellular response to molecule of fungal origin
Biological Process	GO:0034614	cellular response to reactive oxygen species
Biological Process	GO:0002553	histamine secretion by mast cell
Biological Process	GO:0007249	I-kappaB kinase/NF-kappaB signaling
Biological Process	GO:0045087	innate immune response
Biological Process	GO:0030889	negative regulation of B cell proliferation
Biological Process	GO:0001818	negative regulation of cytokine production
Biological Process	GO:0018108	peptidyl-tyrosine phosphorylation
Biological Process	GO:0001812	positive regulation of type I hypersensitivity
Biological Process	GO:0001805	positive regulation of type III hypersensitivity
Biological Process	GO:0046777	protein autophosphorylation
Biological Process	GO:0006468	protein phosphorylation
Biological Process	GO:0010033	response to organic substance
molecular function	GO:0005524	ATP binding
molecular function	GO:0042802	identical protein binding
molecular function	GO:0046872	metal ion binding
molecular function	GO:0004715	non-membrane spanning protein tyrosine kinase activity
molecular function	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding
molecular function	GO:0004713	protein tyrosine kinase activity
cellular component	GO:0005737	cytoplasm
cellular component	GO:0031410	cytoplasmic vesicle
cellular component	GO:0005829	cytosol
cellular component	GO:0042629	mast cell granule
cellular component	GO:0045121	membrane raft
cellular component	GO:0005634	nucleus
cellular component	GO:0048471	perinuclear region of cytoplasm
cellular component	GO:0005886	plasma membrane

Reactome

Pathway Id	Pathway Name

Target protein-related diseases

Disease

CUI Id	BXGD Id	Disease Name	Disease Class

Target protein-related compounds

Compounds

BXGC Id	Compound Name	Strcuture	Molecular Weight
BXGC0036869	Harpagoside		494.18

The target protein-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compound^{? Number of compound in food, higher numbers indicate the food are more associated with the protein}