protein

Showing entry for Antigen peptide transporter 1

General Target Information
BXGT Id	BXGT009917
Protein Name	Antigen peptide transporter 1
Uniport Id	P36370
Gene	Tap1
Gene Id
Domain	ABC_membrane; ABC_tran
Pfam	PF00664 PF00005
Organism	Rattus norvegicus (Rat)

Target protein affiliated biological pathways

KEGG

Class	Subclass	KEGG Id	Pathway Name

Gene Ontology

GO Type	GO Id	Gene Ontology
Biological Process	GO:0002250	adaptive immune response
Biological Process	GO:0019885	antigen processing and presentation of endogenous peptide antigen via MHC class I
Biological Process	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
Biological Process	GO:0046967	cytosol to endoplasmic reticulum transport
Biological Process	GO:0006952	defense response
Biological Process	GO:0046968	peptide antigen transport
Biological Process	GO:0015833	peptide transport
Biological Process	GO:0042270	protection from natural killer cell mediated cytotoxicity
Biological Process	GO:0015031	protein transport
Biological Process	GO:0055085	transmembrane transport
molecular function	GO:0043531	ADP binding
molecular function	GO:0016887	ATPase activity
molecular function	GO:0015433	ATPase-coupled peptide antigen transmembrane transporter activity
molecular function	GO:0015440	ATPase-coupled peptide transmembrane transporter activity
molecular function	GO:0042626	ATPase-coupled transmembrane transporter activity
molecular function	GO:0005524	ATP binding
molecular function	GO:0023029	MHC class Ib protein binding
molecular function	GO:0042288	MHC class I protein binding
molecular function	GO:0000166	nucleotide binding
molecular function	GO:1904680	peptide transmembrane transporter activity
molecular function	GO:0044877	protein-containing complex binding
molecular function	GO:0042803	protein homodimerization activity
molecular function	GO:0046978	TAP1 binding
molecular function	GO:0046979	TAP2 binding
molecular function	GO:0046980	tapasin binding
cellular component	GO:0030176	integral component of endoplasmic reticulum membrane
cellular component	GO:0016021	integral component of membrane
cellular component	GO:0043231	intracellular membrane-bounded organelle
cellular component	GO:0042824	MHC class I peptide loading complex
cellular component	GO:0042825	TAP complex

Reactome

Pathway Id	Pathway Name

Target protein-related diseases

Disease

CUI Id	BXGD Id	Disease Name	Disease Class

Target protein-related compounds

Compounds

BXGC Id	Compound Name	Strcuture	Molecular Weight
BXGC0000436	Glycerol		92.09
BXGC0002588	Magnesium		24.31
BXGC0006198	Citric acid		192.12

The target protein-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compound^{? Number of compound in food, higher numbers indicate the food are more associated with the protein}