Showing entry for ADP-ribosylation factor-like protein 2


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT009919
Protein NameADP-ribosylation factor-like protein 2
Uniport IdP36404
GeneARL2
Gene Id402
DomainArf
Pfam PF00025  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0070830 bicellular tight junction assembly
Biological Process GO:0007098 centrosome cycle
Biological Process GO:0051457 maintenance of protein location in nucleus
Biological Process GO:0034260 negative regulation of GTPase activity
Biological Process GO:0010811 positive regulation of cell-substrate adhesion
Biological Process GO:0031116 positive regulation of microtubule polymerization
Biological Process GO:0050796 regulation of insulin secretion
Biological Process GO:0031113 regulation of microtubule polymerization
Biological Process GO:0007021 tubulin complex assembly
molecular function GO:0019003 GDP binding
molecular function GO:0003924 GTPase activity
molecular function GO:0005095 GTPase inhibitor activity
molecular function GO:0005525 GTP binding
cellular component GO:0005813 centrosome
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0005925 focal adhesion
cellular component GO:0005794 Golgi apparatus
cellular component GO:0016328 lateral plasma membrane
cellular component GO:0015630 microtubule cytoskeleton
cellular component GO:0005758 mitochondrial intermembrane space
cellular component GO:0005759 mitochondrial matrix
cellular component GO:0005730 nucleolus
cellular component GO:0005654 nucleoplasm
cellular component GO:0005634 nucleus
Reactome
Pathway Id Pathway Name
R-HSA-1280215 Cytokine Signaling in Immune system
R-HSA-162582 Signal Transduction
R-HSA-168256 Immune System
R-HSA-382551 Transport of small molecules
R-HSA-389977 Post-chaperonin tubulin folding pathway
R-HSA-391251 Protein folding
R-HSA-392499 Metabolism of proteins
R-HSA-425397 Transport of vitamins, nucleosides, and related molecules
R-HSA-425407 SLC-mediated transmembrane transport
R-HSA-5673001 RAF/MAP kinase cascade
R-HSA-5683057 MAPK family signaling cascades
R-HSA-5684996 MAPK1/MAPK3 signaling
R-HSA-83936 Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane
R-HSA-9607240 FLT3 Signaling
R-HSA-9648002 RAS processing
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001418 BXGD000050 Adenocarcinoma Neoplasms
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0017638 BXGD001132 Glioma Neoplasms
C0025202 BXGD001832 melanoma Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0029463 BXGD002160 Osteosarcoma Neoplasms
C0035334 BXGD002539 Retinitis Pigmentosa Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0264802 BXGD005430 Dilated cardiomyopathy secondary to metabolic disorder Nutritional and Metabolic Diseases; Cardiovascular Diseases
C0585442 BXGD009593 Osteosarcoma of bone Neoplasms
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C1269955 BXGD012005 Tumor Cell Invasion
C1332986 BXGD012574 Childhood Osteosarcoma Neoplasms
C1384666 BXGD012948 hearing impairment Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C1998028 BXGD016865 Photoreceptor degeneration Eye Diseases
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2674009 BXGD017236 Microcornea, Rod-Cone Dystrophy, Cataract, And Posterior Staphyloma Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C4749856 BXGD024066 Microcornea, rod-cone dystrophy, cataract, posterior staphyloma syndrome Eye Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002588 Magnesium 24.31
BXGC0048845 Guanosine Triphosphate 522.99
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein