Showing entry for GMP reductase 1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT009948
Protein NameGMP reductase 1
Uniport IdP36959
GeneGMPR
Gene Id2766
DomainIMPDH
Pfam PF00478  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.4 Nucleotide metabolism hsa00230 Purine metabolism
1. Metabolism 1.0 Global and overview maps hsa01100 Metabolic pathways
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0043101 purine-containing compound salvage
Biological Process GO:0006144 purine nucleobase metabolic process
Biological Process GO:0006163 purine nucleotide metabolic process
Biological Process GO:0009409 response to cold
molecular function GO:0003920 GMP reductase activity
molecular function GO:0046872 metal ion binding
cellular component GO:0005829 cytosol
cellular component GO:1902560 GMP reductase complex
Reactome
Pathway Id Pathway Name
R-HSA-1430728 Metabolism
R-HSA-15869 Metabolism of nucleotides
R-HSA-74217 Purine salvage
R-HSA-8956321 Nucleotide salvage
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0014772 BXGD000948 Red Blood Cell Count measurement
C0025202 BXGD001832 melanoma Neoplasms
C0087031 BXGD003319 Juvenile-Onset Still Disease Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0206161 BXGD004167 Reticulocyte count (procedure)
C0427460 BXGD008616 Red cell distribution width determination
C0429028 BXGD008646 QT interval feature (observable entity)
C0518015 BXGD009068 Hemoglobin measurement
C0524587 BXGD009232 Mean Corpuscular Volume (result)
C1261502 BXGD011856 Finding of Mean Corpuscular Hemoglobin
C1269683 BXGD012001 Major Depressive Disorder Mental Disorders
C1269955 BXGD012005 Tumor Cell Invasion
C1304746 BXGD012343 RDW - Red blood cell distribution width result
C3495559 BXGD018994 Juvenile arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C3714758 BXGD019431 Juvenile psoriatic arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C4528257 BXGD023159 Corpuscular Hemoglobin Concentration Mean
C4552091 BXGD023485 Polyarthritis, Juvenile, Rheumatoid Factor Negative Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C4704862 BXGD023681 Polyarthritis, Juvenile, Rheumatoid Factor Positive Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002591 Potassium 39.1
BXGC0027925 Cpg 363.06
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein