Showing entry for Acetylcholinesterase


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT009967
Protein NameAcetylcholinesterase
Uniport IdP37136
GeneAche
Gene Id83817
DomainAChE_tetra; COesterase
Pfam PF08674   PF00135  
OrganismRattus norvegicus (Rat)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006581 acetylcholine catabolic process
Biological Process GO:0001507 acetylcholine catabolic process in synaptic cleft
Biological Process GO:0008291 acetylcholine metabolic process
Biological Process GO:0007155 cell adhesion
Biological Process GO:0019695 choline metabolic process
Biological Process GO:0070997 neuron death
Biological Process GO:0045212 neurotransmitter receptor biosynthetic process
Biological Process GO:0002076 osteoblast development
Biological Process GO:0050772 positive regulation of axonogenesis
Biological Process GO:0120162 positive regulation of cold-induced thermogenesis
Biological Process GO:0050775 positive regulation of dendrite morphogenesis
Biological Process GO:0031623 receptor internalization
Biological Process GO:0001919 regulation of receptor recycling
Biological Process GO:0060041 retina development in camera-type eye
Biological Process GO:0007416 synapse assembly
molecular function GO:0042166 acetylcholine binding
molecular function GO:0003990 acetylcholinesterase activity
molecular function GO:0033265 choline binding
molecular function GO:0004104 cholinesterase activity
molecular function GO:0005518 collagen binding
molecular function GO:0016787 hydrolase activity
molecular function GO:0042802 identical protein binding
molecular function GO:0043236 laminin binding
molecular function GO:0042803 protein homodimerization activity
molecular function GO:0043621 protein self-association
molecular function GO:0017171 serine hydrolase activity
cellular component GO:0031225 anchored component of membrane
cellular component GO:0030424 axon
cellular component GO:0005604 basement membrane
cellular component GO:0009986 cell surface
cellular component GO:0005737 cytoplasm
cellular component GO:0030425 dendrite
cellular component GO:0005788 endoplasmic reticulum lumen
cellular component GO:0005576 extracellular region
cellular component GO:0005615 extracellular space
cellular component GO:0005794 Golgi apparatus
cellular component GO:0016020 membrane
cellular component GO:0031594 neuromuscular junction
cellular component GO:0043025 neuronal cell body
cellular component GO:0043005 neuron projection
cellular component GO:0005635 nuclear envelope
cellular component GO:0048471 perinuclear region of cytoplasm
cellular component GO:0005886 plasma membrane
cellular component GO:0045211 postsynaptic membrane
cellular component GO:0042734 presynaptic membrane
cellular component GO:0005791 rough endoplasmic reticulum
cellular component GO:0045202 synapse
cellular component GO:0043083 synaptic cleft
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000642 4-Aminobenzoic acid 137.14
BXGC0000663 Papain 206.28
BXGC0001024 Cirsimaritin 314.29
BXGC0001778 Scutellarein 286.24
BXGC0002061 Aloeemodin 270.24
BXGC0004965 Rhein 284.22
BXGC0005624 Genistein 270.24
BXGC0006366 trans-Ferulic acid 194.18
BXGC0015867 4-[4-O-(beta-D-Glucopyranosyl)-beta-D-glucopyranosyloxy]benzyl alcohol 448.16
BXGC0017673 Acaciin 592.18
BXGC0021102 4-[4-O-(alpha-D-Glucopyranosyl)-beta-D-glucopyranosyloxy]benzyl alcohol 448.16
BXGC0021254 1,2,3,9-Tetrahydropyrrolo[2,1-B]Quinazoline 172.1
BXGC0029964 (3R)-3-Isobutyl-3-(beta-D-glucopyranosyloxy)butanedioic acid 1-[4-(beta-D-glucopyranosyloxy)benzyl] ester 620.23
BXGC0030685 Physostigmine 275.16
BXGC0033316 n.a 1066.37
BXGC0034568 N-demethylhuperzinine 256.16
BXGC0035557 Pratol 268.07
BXGC0040408 n.a 488.19
BXGC0040419 (2S,3R)-2,3-Dihydroxy-3-isobutylbutanedioic acid 1-[4-[6-O-(beta-D-glucopyranosyl)-beta-D-glucopyranosyloxy]benzyl]4-[4-(beta-D-glucopyranosyloxy)benzyl] ester 904.32
BXGC0045683 huperzine A 242.14
BXGC0046755 Yohimbine 354.19
BXGC0047867 Dalfampridine 94.05
BXGC0049738 Dexibuprofen 206.13
BXGC0050733 4-[3-O-(beta-D-Glucopyranosyl)-beta-D-glucopyranosyloxy]benzyl alcohol 448.16
BXGC0050816 Galantamine 287.15
BXGC0052157 4-(Ethoxymethyl)phenyl 3-O-(beta-D-glucopyranosyl)-beta-D-glucopyranoside 476.19
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein