Showing entry for Peroxisome proliferator-activated receptor alpha


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT009971
Protein NamePeroxisome proliferator-activated receptor alpha
Uniport IdP37230
GenePpara
Gene Id25747
DomainHormone_recep; zf-C4
Pfam PF00104   PF00105  
OrganismRattus norvegicus (Rat)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0035095 behavioral response to nicotine
Biological Process GO:0030154 cell differentiation
Biological Process GO:0009267 cellular response to starvation
Biological Process GO:0032922 circadian regulation of gene expression
Biological Process GO:0070166 enamel mineralization
Biological Process GO:0008544 epidermis development
Biological Process GO:0006631 fatty acid metabolic process
Biological Process GO:0007507 heart development
Biological Process GO:0009755 hormone-mediated signaling pathway
Biological Process GO:0010876 lipid localization
Biological Process GO:0042157 lipoprotein metabolic process
Biological Process GO:0032099 negative regulation of appetite
Biological Process GO:0045776 negative regulation of blood pressure
Biological Process GO:0061052 negative regulation of cell growth involved in cardiac muscle cell development
Biological Process GO:0010887 negative regulation of cholesterol storage
Biological Process GO:0045820 negative regulation of glycolytic process
Biological Process GO:0050728 negative regulation of inflammatory response
Biological Process GO:1903038 negative regulation of leukocyte cell-cell adhesion
Biological Process GO:0010745 negative regulation of macrophage derived foam cell differentiation
Biological Process GO:1901215 negative regulation of neuron death
Biological Process GO:1902894 negative regulation of pri-miRNA transcription by RNA polymerase II
Biological Process GO:0032091 negative regulation of protein binding
Biological Process GO:0010871 negative regulation of receptor biosynthetic process
Biological Process GO:0010891 negative regulation of sequestering of triglyceride
Biological Process GO:0000122 negative regulation of transcription by RNA polymerase II
Biological Process GO:0045923 positive regulation of fatty acid metabolic process
Biological Process GO:0046321 positive regulation of fatty acid oxidation
Biological Process GO:0045722 positive regulation of gluconeogenesis
Biological Process GO:0045893 positive regulation of transcription, DNA-templated
Biological Process GO:0045944 positive regulation of transcription by RNA polymerase II
Biological Process GO:0010565 regulation of cellular ketone metabolic process
Biological Process GO:0042752 regulation of circadian rhythm
Biological Process GO:0019217 regulation of fatty acid metabolic process
Biological Process GO:0010468 regulation of gene expression
Biological Process GO:0019216 regulation of lipid metabolic process
Biological Process GO:0010883 regulation of lipid storage
Biological Process GO:0006355 regulation of transcription, DNA-templated
Biological Process GO:0045471 response to ethanol
Biological Process GO:0001666 response to hypoxia
Biological Process GO:0032868 response to insulin
Biological Process GO:0033993 response to lipid
Biological Process GO:0014070 response to organic cyclic compound
Biological Process GO:0042060 wound healing
molecular function GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
molecular function GO:0003700 DNA-binding transcription factor activity
molecular function GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific
molecular function GO:0008144 drug binding
molecular function GO:0008289 lipid binding
molecular function GO:0097371 MDM2/MDM4 family protein binding
molecular function GO:0051525 NFAT protein binding
molecular function GO:0004879 nuclear receptor activity
molecular function GO:0019902 phosphatase binding
molecular function GO:0044877 protein-containing complex binding
molecular function GO:0019904 protein domain specific binding
molecular function GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
molecular function GO:0001103 RNA polymerase II repressing transcription factor binding
molecular function GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
molecular function GO:0043565 sequence-specific DNA binding
molecular function GO:0038023 signaling receptor activity
molecular function GO:0003707 steroid hormone receptor activity
molecular function GO:0001223 transcription coactivator binding
molecular function GO:0008134 transcription factor binding
molecular function GO:0031624 ubiquitin conjugating enzyme binding
molecular function GO:0008270 zinc ion binding
cellular component GO:0005654 nucleoplasm
cellular component GO:0005634 nucleus
cellular component GO:0090575 RNA polymerase II transcription regulator complex
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000894 2-Methylthioribosyl-trans-zeatin 323.8
BXGC0039750 Resveratrol 4'-Methyl Ether 242.09
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein