Showing entry for Tyrosine-protein kinase Fyn


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT010132
Protein NameTyrosine-protein kinase Fyn
Uniport IdP39688
GeneFyn
Gene Id14360
DomainPkinase_Tyr; SH2; SH3_1
Pfam PF07714   PF00017   PF00018  
OrganismMus musculus (Mouse)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0050798 activated T cell proliferation
Biological Process GO:0002250 adaptive immune response
Biological Process GO:0030154 cell differentiation
Biological Process GO:0007166 cell surface receptor signaling pathway
Biological Process GO:1904646 cellular response to amyloid-beta
Biological Process GO:1905430 cellular response to glycine
Biological Process GO:1905232 cellular response to L-glutamate
Biological Process GO:0071375 cellular response to peptide hormone stimulus
Biological Process GO:0036120 cellular response to platelet-derived growth factor stimulus
Biological Process GO:0071560 cellular response to transforming growth factor beta stimulus
Biological Process GO:0048813 dendrite morphogenesis
Biological Process GO:0050966 detection of mechanical stimulus involved in sensory perception of pain
Biological Process GO:0030900 forebrain development
Biological Process GO:0003015 heart process
Biological Process GO:0045087 innate immune response
Biological Process GO:0050804 modulation of chemical synaptic transmission
Biological Process GO:0042552 myelination
Biological Process GO:1902951 negative regulation of dendritic spine maintenance
Biological Process GO:2001240 negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
Biological Process GO:0010629 negative regulation of gene expression
Biological Process GO:0010730 negative regulation of hydrogen peroxide biosynthetic process
Biological Process GO:0043524 negative regulation of neuron apoptotic process
Biological Process GO:1903202 negative regulation of oxidative stress-induced cell death
Biological Process GO:0042177 negative regulation of protein catabolic process
Biological Process GO:0031397 negative regulation of protein ubiquitination
Biological Process GO:0001764 neuron migration
Biological Process GO:0038083 peptidyl-tyrosine autophosphorylation
Biological Process GO:0018108 peptidyl-tyrosine phosphorylation
Biological Process GO:2001056 positive regulation of cysteine-type endopeptidase activity
Biological Process GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
Biological Process GO:1901216 positive regulation of neuron death
Biological Process GO:0010976 positive regulation of neuron projection development
Biological Process GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling
Biological Process GO:1900182 positive regulation of protein localization to nucleus
Biological Process GO:0090314 positive regulation of protein targeting to membrane
Biological Process GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein
Biological Process GO:0046777 protein autophosphorylation
Biological Process GO:0006468 protein phosphorylation
Biological Process GO:1905664 regulation of calcium ion import across plasma membrane
Biological Process GO:0042127 regulation of cell population proliferation
Biological Process GO:0008360 regulation of cell shape
Biological Process GO:1900449 regulation of glutamate receptor signaling pathway
Biological Process GO:0050730 regulation of peptidyl-tyrosine phosphorylation
Biological Process GO:1904645 response to amyloid-beta
Biological Process GO:0042493 response to drug
Biological Process GO:0045471 response to ethanol
Biological Process GO:0042542 response to hydrogen peroxide
Biological Process GO:0000304 response to singlet oxygen
Biological Process GO:0050852 T cell receptor signaling pathway
Biological Process GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
molecular function GO:0043014 alpha-tubulin binding
molecular function GO:0005524 ATP binding
molecular function GO:0042609 CD4 receptor binding
molecular function GO:0042610 CD8 receptor binding
molecular function GO:0097718 disordered domain specific binding
molecular function GO:0019899 enzyme binding
molecular function GO:0046875 ephrin receptor binding
molecular function GO:0001664 G protein-coupled receptor binding
molecular function GO:0070851 growth factor receptor binding
molecular function GO:0042802 identical protein binding
molecular function GO:0044325 ion channel binding
molecular function GO:0046872 metal ion binding
molecular function GO:0004715 non-membrane spanning protein tyrosine kinase activity
molecular function GO:0051428 peptide hormone receptor binding
molecular function GO:0043548 phosphatidylinositol 3-kinase binding
molecular function GO:0044877 protein-containing complex binding
molecular function GO:0004672 protein kinase activity
molecular function GO:0004713 protein tyrosine kinase activity
molecular function GO:0005102 signaling receptor binding
molecular function GO:0048156 tau protein binding
molecular function GO:0042608 T cell receptor binding
molecular function GO:0015631 tubulin binding
molecular function GO:0031802 type 5 metabotropic glutamate receptor binding
cellular component GO:0005884 actin filament
cellular component GO:0044297 cell body
cellular component GO:0071944 cell periphery
cellular component GO:0005829 cytosol
cellular component GO:0030425 dendrite
cellular component GO:0005768 endosome
cellular component GO:0031234 extrinsic component of cytoplasmic side of plasma membrane
cellular component GO:0097386 glial cell projection
cellular component GO:0098978 glutamatergic synapse
cellular component GO:0043231 intracellular membrane-bounded organelle
cellular component GO:0016020 membrane
cellular component GO:0045121 membrane raft
cellular component GO:0005739 mitochondrion
cellular component GO:0005634 nucleus
cellular component GO:0097038 perinuclear endoplasmic reticulum
cellular component GO:0048471 perinuclear region of cytoplasm
cellular component GO:0005886 plasma membrane
cellular component GO:0014069 postsynaptic density
cellular component GO:0099092 postsynaptic density, intracellular component
cellular component GO:0098685 Schaffer collateral - CA1 synapse
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0003705 Chloride 35.45
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein