Showing entry for ATP-dependent translocase ABCB1



                       
General Target Information
BXGT IdBXGT010370
Protein NameATP-dependent translocase ABCB1
Uniport IdP43245
GeneAbcb1
Gene Id
DomainABC_membrane; ABC_tran
Pfam PF00664   PF00005  
OrganismRattus norvegicus (Rat)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007420 brain development
Biological Process GO:0071217 cellular response to external biotic stimulus
Biological Process GO:0071356 cellular response to tumor necrosis factor
Biological Process GO:0099040 ceramide translocation
Biological Process GO:0014045 establishment of endothelial blood-brain barrier
Biological Process GO:0007595 lactation
Biological Process GO:0045332 phospholipid translocation
Biological Process GO:0001890 placenta development
Biological Process GO:0097327 response to antineoplastic agent
Biological Process GO:0046685 response to arsenic-containing substance
Biological Process GO:0042493 response to drug
Biological Process GO:0033595 response to genistein
Biological Process GO:1903416 response to glycoside
Biological Process GO:0001666 response to hypoxia
Biological Process GO:0010212 response to ionizing radiation
Biological Process GO:0032496 response to lipopolysaccharide
Biological Process GO:0010046 response to mycotoxin
Biological Process GO:0014070 response to organic cyclic compound
Biological Process GO:0048545 response to steroid hormone
Biological Process GO:0033189 response to vitamin A
Biological Process GO:0061843 Sertoli cell barrier remodeling
molecular function GO:0016887 ATPase activity
molecular function GO:0042626 ATPase-coupled transmembrane transporter activity
molecular function GO:0008559 ATPase-coupled xenobiotic transmembrane transporter activity
molecular function GO:0005524 ATP binding
molecular function GO:0099038 ceramide floppase activity
molecular function GO:0140328 floppase activity
molecular function GO:0090554 phosphatidylcholine floppase activity
molecular function GO:0090555 phosphatidylethanolamine flippase activity
cellular component GO:0016324 apical plasma membrane
cellular component GO:0098591 external side of apical plasma membrane
cellular component GO:0000139 Golgi membrane
cellular component GO:0016021 integral component of membrane
cellular component GO:0046581 intercellular canaliculus
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000563 1H-Indole-3-methanol 147.17
BXGC0034783 Doxorubicin 543.17
BXGC0044017 Verapamil 454.28
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein