Showing entry for Mitogen-activated protein kinase 8


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT010494
Protein NameMitogen-activated protein kinase 8
Uniport IdP45983
GeneMAPK8
Gene Id5599
DomainPkinase
Pfam PF00069  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
6. Human Diseases 6.12 Drug resistance: Antineoplastic hsa01522 Endocrine resistance
3. Environmental Information Processing 3.2 Signal transduction hsa04010 MAPK signaling pathway
3. Environmental Information Processing 3.2 Signal transduction hsa04012 ErbB signaling pathway
3. Environmental Information Processing 3.2 Signal transduction hsa04014 Ras signaling pathway
3. Environmental Information Processing 3.2 Signal transduction hsa04024 cAMP signaling pathway
3. Environmental Information Processing 3.2 Signal transduction hsa04068 FoxO signaling pathway
3. Environmental Information Processing 3.2 Signal transduction hsa04071 Sphingolipid signaling pathway
4. Cellular Processes 4.1 Transport and catabolism hsa04137 Mitophagy - animal
4. Cellular Processes 4.1 Transport and catabolism hsa04140 Autophagy - animal
2. Genetic Information Processing 2.3 Folding, sorting and degradation hsa04141 Protein processing in endoplasmic reticulum
4. Cellular Processes 4.2 Cell growth and death hsa04210 Apoptosis
4. Cellular Processes 4.2 Cell growth and death hsa04215 Apoptosis - multiple species
4. Cellular Processes 4.2 Cell growth and death hsa04217 Necroptosis
3. Environmental Information Processing 3.2 Signal transduction hsa04310 Wnt signaling pathway
5. Organismal Systems 5.8 Development hsa04380 Osteoclast differentiation
4. Cellular Processes 4.3 Cellular community - eukaryotes hsa04510 Focal adhesion
4. Cellular Processes 4.3 Cellular community - eukaryotes hsa04530 Tight junction
5. Organismal Systems 5.1 Immune system hsa04620 Toll-like receptor signaling pathway
5. Organismal Systems 5.1 Immune system hsa04621 NOD-like receptor signaling pathway
5. Organismal Systems 5.1 Immune system hsa04622 RIG-I-like receptor signaling pathway
5. Organismal Systems 5.1 Immune system hsa04625 C-type lectin receptor signaling pathway
5. Organismal Systems 5.1 Immune system hsa04657 IL-17 signaling pathway
5. Organismal Systems 5.1 Immune system hsa04658 Th1 and Th2 cell differentiation
5. Organismal Systems 5.1 Immune system hsa04659 Th17 cell differentiation
5. Organismal Systems 5.1 Immune system hsa04664 Fc epsilon RI signaling pathway
3. Environmental Information Processing 3.2 Signal transduction hsa04668 TNF signaling pathway
5. Organismal Systems 5.6 Nervous system hsa04722 Neurotrophin signaling pathway
5. Organismal Systems 5.6 Nervous system hsa04723 Retrograde endocannabinoid signaling
5. Organismal Systems 5.6 Nervous system hsa04728 Dopaminergic synapse
5. Organismal Systems 5.7 Sensory system hsa04750 Inflammatory mediator regulation of TRP channels
5. Organismal Systems 5.2 Endocrine system hsa04910 Insulin signaling pathway
5. Organismal Systems 5.2 Endocrine system hsa04912 GnRH signaling pathway
5. Organismal Systems 5.2 Endocrine system hsa04914 Progesterone-mediated oocyte maturation
5. Organismal Systems 5.2 Endocrine system hsa04917 Prolactin signaling pathway
5. Organismal Systems 5.2 Endocrine system hsa04920 Adipocytokine signaling pathway
5. Organismal Systems 5.2 Endocrine system hsa04926 Relaxin signaling pathway
6. Human Diseases 6.7 Endocrine and metabolic diseases hsa04930 Type II diabetes mellitus
6. Human Diseases 6.7 Endocrine and metabolic diseases hsa04931 Insulin resistance
6. Human Diseases 6.7 Endocrine and metabolic diseases hsa04932 Non-alcoholic fatty liver disease (NAFLD)
6. Human Diseases 6.7 Endocrine and metabolic diseases hsa04933 AGE-RAGE signaling pathway in diabetic complications
6. Human Diseases 6.8 Infectious diseases: Bacterial hsa05120 Epithelial cell signaling in Helicobacter pylori infection
6. Human Diseases 6.8 Infectious diseases: Bacterial hsa05131 Shigellosis
6. Human Diseases 6.8 Infectious diseases: Bacterial hsa05132 Salmonella infection
6. Human Diseases 6.8 Infectious diseases: Bacterial hsa05133 Pertussis
6. Human Diseases 6.8 Infectious diseases: Bacterial hsa05135 Yersinia infection
6. Human Diseases 6.10 Infectious diseases: Parasitic hsa05142 Chagas disease (American trypanosomiasis)
6. Human Diseases 6.10 Infectious diseases: Parasitic hsa05145 Toxoplasmosis
6. Human Diseases 6.8 Infectious diseases: Bacterial hsa05152 Tuberculosis
6. Human Diseases 6.9 Infectious diseases: Viral hsa05161 Hepatitis B
6. Human Diseases 6.9 Infectious diseases: Viral hsa05162 Measles
6. Human Diseases 6.9 Infectious diseases: Viral hsa05166 Human T-cell leukemia virus 1 infection
6. Human Diseases 6.9 Infectious diseases: Viral hsa05167 Kaposi sarcoma-associated herpesvirus infection
6. Human Diseases 6.9 Infectious diseases: Viral hsa05169 Epstein-Barr virus infection
6. Human Diseases 6.9 Infectious diseases: Viral hsa05170 Human immunodeficiency virus 1 infection
6. Human Diseases 6.1 Cancers: Overview hsa05200 Pathways in cancer
6. Human Diseases 6.2 Cancers: Specific types hsa05210 Colorectal cancer
6. Human Diseases 6.2 Cancers: Specific types hsa05212 Pancreatic cancer
6. Human Diseases 6.1 Cancers: Overview hsa05231 Choline metabolism in cancer
6. Human Diseases 6.6 Cardiovascular diseases hsa05418 Fluid shear stress and atherosclerosis
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0034198 cellular response to amino acid starvation
Biological Process GO:0071276 cellular response to cadmium ion
Biological Process GO:0071345 cellular response to cytokine stimulus
Biological Process GO:0071222 cellular response to lipopolysaccharide
Biological Process GO:0071260 cellular response to mechanical stimulus
Biological Process GO:0034614 cellular response to reactive oxygen species
Biological Process GO:0038095 Fc-epsilon receptor signaling pathway
Biological Process GO:0035556 intracellular signal transduction
Biological Process GO:0007254 JNK cascade
Biological Process GO:0007258 JUN phosphorylation
Biological Process GO:0043066 negative regulation of apoptotic process
Biological Process GO:0032091 negative regulation of protein binding
Biological Process GO:0018105 peptidyl-serine phosphorylation
Biological Process GO:0018107 peptidyl-threonine phosphorylation
Biological Process GO:0043065 positive regulation of apoptotic process
Biological Process GO:0031281 positive regulation of cyclase activity
Biological Process GO:0090045 positive regulation of deacetylase activity
Biological Process GO:0010628 positive regulation of gene expression
Biological Process GO:1900740 positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
Biological Process GO:0051247 positive regulation of protein metabolic process
Biological Process GO:0006468 protein phosphorylation
Biological Process GO:0042752 regulation of circadian rhythm
Biological Process GO:0051090 regulation of DNA-binding transcription factor activity
Biological Process GO:1902595 regulation of DNA replication origin binding
Biological Process GO:0010468 regulation of gene expression
Biological Process GO:0016241 regulation of macroautophagy
Biological Process GO:0032880 regulation of protein localization
Biological Process GO:0009612 response to mechanical stimulus
Biological Process GO:0009411 response to UV
Biological Process GO:0048511 rhythmic process
Biological Process GO:0051403 stress-activated MAPK cascade
molecular function GO:0005524 ATP binding
molecular function GO:0019899 enzyme binding
molecular function GO:0042826 histone deacetylase binding
molecular function GO:0035033 histone deacetylase regulator activity
molecular function GO:0004705 JUN kinase activity
molecular function GO:0016301 kinase activity
molecular function GO:0004707 MAP kinase activity
molecular function GO:0004674 protein serine/threonine kinase activity
cellular component GO:0030424 axon
cellular component GO:0097441 basal dendrite
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0005739 mitochondrion
cellular component GO:0005654 nucleoplasm
cellular component GO:0005634 nucleus
cellular component GO:0045202 synapse
Reactome
Pathway Id Pathway Name
R-HSA-109581 Apoptosis
R-HSA-109606 Intrinsic Pathway for Apoptosis
R-HSA-111446 Activation of BIM and translocation to mitochondria
R-HSA-114452 Activation of BH3-only proteins
R-HSA-1266738 Developmental Biology
R-HSA-1280215 Cytokine Signaling in Immune system
R-HSA-139910 Activation of BMF and translocation to mitochondria
R-HSA-162582 Signal Transduction
R-HSA-162582 Signal Transduction
R-HSA-1643685 Disease
R-HSA-166016 Toll Like Receptor 4 (TLR4) Cascade
R-HSA-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane
R-HSA-166166 MyD88-independent TLR4 cascade
R-HSA-168138 Toll Like Receptor 9 (TLR9) Cascade
R-HSA-168142 Toll Like Receptor 10 (TLR10) Cascade
R-HSA-168164 Toll Like Receptor 3 (TLR3) Cascade
R-HSA-168176 Toll Like Receptor 5 (TLR5) Cascade
R-HSA-168179 Toll Like Receptor TLR1:TLR2 Cascade
R-HSA-168181 Toll Like Receptor 7/8 (TLR7/8) Cascade
R-HSA-168188 Toll Like Receptor TLR6:TLR2 Cascade
R-HSA-168249 Innate Immune System
R-HSA-168256 Immune System
R-HSA-168898 Toll-like Receptor Cascades
R-HSA-181438 Toll Like Receptor 2 (TLR2) Cascade
R-HSA-193648 NRAGE signals death through JNK
R-HSA-193648 NRAGE signals death through JNK
R-HSA-193704 p75 NTR receptor-mediated signalling
R-HSA-193704 p75 NTR receptor-mediated signalling
R-HSA-204998 Cell death signalling via NRAGE, NRIF and NADE
R-HSA-204998 Cell death signalling via NRAGE, NRIF and NADE
R-HSA-205043 NRIF signals cell death from the nucleus
R-HSA-2262752 Cellular responses to stress
R-HSA-2454202 Fc epsilon receptor (FCERI) signaling
R-HSA-2559580 Oxidative Stress Induced Senescence
R-HSA-2559583 Cellular Senescence
R-HSA-2871796 FCERI mediated MAPK activation
R-HSA-373752 Netrin-1 signaling
R-HSA-376172 DSCAM interactions
R-HSA-422475 Axon guidance
R-HSA-446652 Interleukin-1 family signaling
R-HSA-448424 Interleukin-17 signaling
R-HSA-449147 Signaling by Interleukins
R-HSA-450282 MAPK targets/ Nuclear events mediated by MAP kinases
R-HSA-450294 MAP kinase activation
R-HSA-450321 JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
R-HSA-450341 Activation of the AP-1 family of transcription factors
R-HSA-5357801 Programmed Cell Death
R-HSA-5663205 Infectious disease
R-HSA-5693532 DNA Double-Strand Break Repair
R-HSA-5693565 Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
R-HSA-5693606 DNA Double Strand Break Response
R-HSA-73887 Death Receptor Signalling
R-HSA-73887 Death Receptor Signalling
R-HSA-73894 DNA Repair
R-HSA-8953897 Cellular responses to external stimuli
R-HSA-9007892 Interleukin-38 signaling
R-HSA-937061 TRIF(TICAM1)-mediated TLR4 signaling
R-HSA-9658195 Leishmania infection
R-HSA-9664420 Killing mechanisms
R-HSA-9673324 WNT5:FZD7-mediated leishmania damping
R-HSA-9675108 Nervous system development
R-HSA-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation
R-HSA-975155 MyD88 dependent cascade initiated on endosome
R-HSA-975871 MyD88 cascade initiated on plasma membrane
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001193 BXGD000030 Apert syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0001339 BXGD000041 Acute pancreatitis Digestive System Diseases
C0001815 BXGD000078 Primary Myelofibrosis Hemic and Lymphatic Diseases
C0001973 BXGD000095 Alcoholic Intoxication, Chronic Chemically-Induced Disorders; Mental Disorders
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0002438 BXGD000113 Amebiasis Infections
C0002622 BXGD000119 Amnesia Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0002726 BXGD000125 Amyloidosis Nutritional and Metabolic Diseases
C0002736 BXGD000127 Amyotrophic Lateral Sclerosis Nutritional and Metabolic Diseases; Nervous System Diseases
C0002793 BXGD000130 Anaplasia Pathological Conditions, Signs and Symptoms; Neoplasms
C0002895 BXGD000152 Anemia, Sickle Cell Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0003467 BXGD000194 Anxiety Behavior and Behavior Mechanisms
C0003469 BXGD000195 Anxiety Disorders Mental Disorders
C0003486 BXGD000197 Aortic Aneurysm Cardiovascular Diseases
C0003504 BXGD000202 Aortic Valve Insufficiency Cardiovascular Diseases
C0003850 BXGD000225 Arteriosclerosis Cardiovascular Diseases
C0003864 BXGD000231 Arthritis Musculoskeletal Diseases
C0003873 BXGD000236 Rheumatoid Arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0004096 BXGD000252 Asthma Respiratory Tract Diseases; Immune System Diseases
C0004114 BXGD000255 Astrocytoma Neoplasms
C0004153 BXGD000260 Atherosclerosis Cardiovascular Diseases
C0004623 BXGD000282 Bacterial Infections Infections
C0004763 BXGD000289 Barrett Esophagus Digestive System Diseases; Neoplasms
C0005398 BXGD000311 Cholestasis, Extrahepatic Digestive System Diseases
C0005684 BXGD000319 Malignant neoplasm of urinary bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0005695 BXGD000323 Bladder Neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0005699 BXGD000325 Blast Phase Pathological Conditions, Signs and Symptoms; Neoplasms; Hemic and Lymphatic Diseases
C0005940 BXGD000352 Bone Diseases Musculoskeletal Diseases
C0005944 BXGD000355 Metabolic Bone Disorder Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0006118 BXGD000372 Brain Neoplasms Neoplasms; Nervous System Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006277 BXGD000387 Bronchitis Infections; Respiratory Tract Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0006845 BXGD000410 Candidiasis, Chronic Mucocutaneous Infections; Skin and Connective Tissue Diseases
C0007097 BXGD000424 Carcinoma Neoplasms
C0007102 BXGD000425 Malignant tumor of colon Digestive System Diseases; Neoplasms
C0007103 BXGD000426 Malignant neoplasm of endometrium Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0007107 BXGD000428 Malignant neoplasm of larynx Neoplasms; Respiratory Tract Diseases; Otorhinolaryngologic Diseases
C0007113 BXGD000430 Rectal Carcinoma Digestive System Diseases; Neoplasms
C0007115 BXGD000432 Malignant neoplasm of thyroid Neoplasms; Endocrine System Diseases
C0007131 BXGD000441 Non-Small Cell Lung Carcinoma Neoplasms; Respiratory Tract Diseases
C0007134 BXGD000443 Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0007137 BXGD000445 Squamous cell carcinoma Neoplasms
C0007196 BXGD000453 Restrictive cardiomyopathy Cardiovascular Diseases
C0007222 BXGD000454 Cardiovascular Diseases Cardiovascular Diseases
C0007621 BXGD000468 Neoplastic Cell Transformation Pathological Conditions, Signs and Symptoms; Neoplasms
C0007682 BXGD000471 CNS disorder Nervous System Diseases
C0007785 BXGD000485 Cerebral Infarction Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0007786 BXGD000486 Brain Ischemia Nervous System Diseases; Cardiovascular Diseases
C0007847 BXGD000492 Malignant tumor of cervix Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0008055 BXGD000514 Chikungunya Fever Infections
C0008272 BXGD000521 Asiderotic anemia Hemic and Lymphatic Diseases
C0008370 BXGD000534 Cholestasis Digestive System Diseases
C0009207 BXGD000593 Cockayne Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Musculoskeletal Diseases; Nervous System Diseases
C0009241 BXGD000595 Cognition Disorders Mental Disorders
C0009319 BXGD000596 Colitis Digestive System Diseases
C0009324 BXGD000597 Ulcerative Colitis Digestive System Diseases
C0009375 BXGD000602 Colonic Neoplasms Digestive System Diseases; Neoplasms
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0009404 BXGD000606 Colorectal Neoplasms Digestive System Diseases; Neoplasms
C0009766 BXGD000629 Allergic Conjunctivitis Eye Diseases; Immune System Diseases
C0009782 BXGD000631 Connective Tissue Diseases Skin and Connective Tissue Diseases
C0010054 BXGD000647 Coronary Arteriosclerosis Cardiovascular Diseases
C0010068 BXGD000648 Coronary heart disease Cardiovascular Diseases
C0010278 BXGD000660 Craniosynostosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0010346 BXGD000664 Crohn Disease Digestive System Diseases
C0010674 BXGD000683 Cystic Fibrosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Respiratory Tract Diseases
C0011195 BXGD000702 Dejerine-Sottas Disease (disorder) Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0011570 BXGD000729 Mental Depression Behavior and Behavior Mechanisms
C0011581 BXGD000733 Depressive disorder Mental Disorders
C0011603 BXGD000734 Dermatitis Skin and Connective Tissue Diseases
C0011615 BXGD000738 Dermatitis, Atopic Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases; Immune System Diseases
C0011847 BXGD000749 Diabetes Endocrine System Diseases
C0011849 BXGD000751 Diabetes Mellitus Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011854 BXGD000753 Diabetes Mellitus, Insulin-Dependent Nutritional and Metabolic Diseases; Immune System Diseases; Endocrine System Diseases
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011881 BXGD000760 Diabetic Nephropathy Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0012739 BXGD000786 Disseminated Intravascular Coagulation Hemic and Lymphatic Diseases
C0013370 BXGD000822 Amebic colitis Digestive System Diseases; Infections
C0013595 BXGD000858 Eczema Skin and Connective Tissue Diseases
C0014175 BXGD000904 Endometriosis Female Urogenital Diseases and Pregnancy Complications
C0014544 BXGD000926 Epilepsy Nervous System Diseases
C0014556 BXGD000932 Epilepsy, Temporal Lobe Nervous System Diseases
C0014599 BXGD000939 Epithelial hyperplasia Pathological Conditions, Signs and Symptoms
C0014859 BXGD000961 Esophageal Neoplasms Digestive System Diseases; Neoplasms
C0015625 BXGD001006 Fanconi Anemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Hemic and Lymphatic Diseases
C0015695 BXGD001013 Fatty Liver Digestive System Diseases
C0015934 BXGD001026 Fetal Growth Retardation Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications
C0015967 BXGD001030 Fever Pathological Conditions, Signs and Symptoms
C0016053 BXGD001041 Fibromyalgia Musculoskeletal Diseases; Nervous System Diseases
C0016057 BXGD001042 Fibrosarcoma Neoplasms
C0017160 BXGD001099 Gastroenteritis Digestive System Diseases
C0017601 BXGD001125 Glaucoma Eye Diseases
C0017636 BXGD001131 Glioblastoma Neoplasms
C0017638 BXGD001132 Glioma Neoplasms
C0018378 BXGD001190 Guillain-Barre Syndrome Immune System Diseases; Nervous System Diseases
C0018553 BXGD001203 Hamartoma Syndrome, Multiple Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms
C0018801 BXGD001226 Heart failure Cardiovascular Diseases
C0018802 BXGD001227 Congestive heart failure Cardiovascular Diseases
C0018834 BXGD001238 Heartburn Pathological Conditions, Signs and Symptoms
C0018965 BXGD001258 Hematuria Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0019158 BXGD001293 Hepatitis Digestive System Diseases
C0019159 BXGD001294 Hepatitis A Digestive System Diseases; Infections
C0019163 BXGD001295 Hepatitis B Digestive System Diseases; Infections
C0019196 BXGD001301 Hepatitis C Digestive System Diseases; Infections
C0019202 BXGD001302 Hepatolenticular Degeneration Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Nutritional and Metabolic Diseases; Nervous System Diseases
C0019337 BXGD001319 Heroin Dependence Chemically-Induced Disorders; Mental Disorders
C0020179 BXGD001363 Huntington Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Mental Disorders
C0020429 BXGD001378 Hyperalgesia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0020456 BXGD001392 Hyperglycemia Nutritional and Metabolic Diseases
C0020459 BXGD001394 Hyperinsulinism Nutritional and Metabolic Diseases
C0020538 BXGD001422 Hypertensive disease Cardiovascular Diseases
C0020615 BXGD001445 Hypoglycemia Nutritional and Metabolic Diseases
C0021051 BXGD001475 Immunologic Deficiency Syndromes Immune System Diseases
C0021390 BXGD001503 Inflammatory Bowel Diseases Digestive System Diseases
C0021400 BXGD001504 Influenza Infections; Respiratory Tract Diseases
C0021670 BXGD001509 insulinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0022408 BXGD001544 Arthropathy Musculoskeletal Diseases
C0022568 BXGD001552 Keratitis Eye Diseases
C0022650 BXGD001568 Kidney Calculi Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0022658 BXGD001570 Kidney Diseases Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0022660 BXGD001571 Kidney Failure, Acute Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0023418 BXGD001642 leukemia Neoplasms
C0023434 BXGD001643 Chronic Lymphocytic Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023440 BXGD001646 Acute Erythroblastic Leukemia Neoplasms; Hemic and Lymphatic Diseases
C0023449 BXGD001650 Acute lymphocytic leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023452 BXGD001651 Childhood Acute Lymphoblastic Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023465 BXGD001656 Acute monocytic leukemia Neoplasms
C0023467 BXGD001658 Leukemia, Myelocytic, Acute Neoplasms
C0023473 BXGD001661 Myeloid Leukemia, Chronic Neoplasms; Hemic and Lymphatic Diseases
C0023487 BXGD001669 Acute Promyelocytic Leukemia Neoplasms
C0023890 BXGD001713 Liver Cirrhosis Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0023895 BXGD001717 Liver diseases Digestive System Diseases
C0023903 BXGD001720 Liver neoplasms Digestive System Diseases; Neoplasms
C0024115 BXGD001732 Lung diseases Respiratory Tract Diseases
C0024117 BXGD001734 Chronic Obstructive Airway Disease Respiratory Tract Diseases
C0024121 BXGD001735 Lung Neoplasms Neoplasms; Respiratory Tract Diseases
C0024299 BXGD001758 Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0024305 BXGD001763 Lymphoma, Non-Hodgkin Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0024623 BXGD001791 Malignant neoplasm of stomach Digestive System Diseases; Neoplasms
C0025149 BXGD001826 Medulloblastoma Neoplasms
C0025202 BXGD001832 melanoma Neoplasms
C0025286 BXGD001850 Meningioma Neoplasms; Nervous System Diseases
C0025500 BXGD001874 Mesothelioma Neoplasms
C0025517 BXGD001875 Metabolic Diseases Nutritional and Metabolic Diseases
C0025958 BXGD001882 Microcephaly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C0026618 BXGD001909 Dental Fluorosis, Acquired Stomatognathic Diseases
C0026764 BXGD001928 Multiple Myeloma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C0026769 BXGD001930 Multiple Sclerosis Immune System Diseases; Nervous System Diseases
C0026837 BXGD001937 Muscle Rigidity Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases
C0026987 BXGD001957 Myelofibrosis Pathological Conditions, Signs and Symptoms; Neoplasms; Hemic and Lymphatic Diseases
C0027051 BXGD001963 Myocardial Infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0027055 BXGD001964 Myocardial Reperfusion Injury Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0027059 BXGD001965 Myocarditis Cardiovascular Diseases
C0027073 BXGD001968 Myofascial Pain Syndromes Musculoskeletal Diseases
C0027341 BXGD001982 Nail-Patella Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases; Musculoskeletal Diseases
C0027430 BXGD001988 Nasal Polyps Pathological Conditions, Signs and Symptoms; Respiratory Tract Diseases; Otorhinolaryngologic Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0027765 BXGD002033 nervous system disorder Nervous System Diseases
C0027794 BXGD002036 Neural Tube Defects Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0027796 BXGD002037 Neuralgia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0027819 BXGD002043 Neuroblastoma Neoplasms
C0027831 BXGD002047 Neurofibromatosis 1 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Nervous System Diseases
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0029132 BXGD002117 Disorder of the optic nerve Eye Diseases; Nervous System Diseases
C0029408 BXGD002137 Degenerative polyarthritis Musculoskeletal Diseases
C0029453 BXGD002154 Osteopenia Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0029456 BXGD002157 Osteoporosis Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0029463 BXGD002160 Osteosarcoma Neoplasms
C0029925 BXGD002181 Ovarian Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0030193 BXGD002191 Pain Pathological Conditions, Signs and Symptoms
C0030297 BXGD002204 Pancreatic Neoplasm Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0030567 BXGD002240 Parkinson Disease Nervous System Diseases
C0030809 BXGD002258 Pemphigus Vulgaris Skin and Connective Tissue Diseases; Immune System Diseases
C0031511 BXGD002304 Pheochromocytoma Neoplasms
C0032000 BXGD002318 Pituitary Adenoma Neoplasms; Nervous System Diseases; Endocrine System Diseases
C0032285 BXGD002344 Pneumonia Infections; Respiratory Tract Diseases
C0032460 BXGD002355 Polycystic Ovary Syndrome Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0032461 BXGD002356 Polycythemia Hemic and Lymphatic Diseases
C0032580 BXGD002362 Adenomatous Polyposis Coli Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Neoplasms
C0032927 BXGD002381 Precancerous Conditions Neoplasms
C0033578 BXGD002408 Prostatic Neoplasms Neoplasms; Male Urogenital Diseases
C0033860 BXGD002438 Psoriasis Skin and Connective Tissue Diseases
C0034069 BXGD002458 Pulmonary Fibrosis Respiratory Tract Diseases
C0035112 BXGD002508 Reoviridae Infections Infections
C0035126 BXGD002509 Reperfusion Injury Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0035204 BXGD002511 Respiration Disorders Respiratory Tract Diseases
C0035222 BXGD002513 Respiratory Distress Syndrome, Adult Respiratory Tract Diseases
C0035235 BXGD002519 Respiratory Syncytial Virus Infections Infections
C0035242 BXGD002521 Respiratory Tract Diseases Respiratory Tract Diseases
C0035335 BXGD002540 Retinoblastoma Neoplasms; Eye Diseases
C0035412 BXGD002548 Rhabdomyosarcoma Neoplasms
C0035869 BXGD002569 Rotavirus Infections Infections
C0036220 BXGD002587 Kaposi Sarcoma Neoplasms; Infections
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0036690 BXGD002632 Septicemia Pathological Conditions, Signs and Symptoms; Infections
C0037274 BXGD002676 Dermatologic disorders Skin and Connective Tissue Diseases
C0037284 BXGD002679 Skin lesion Skin and Connective Tissue Diseases
C0037773 BXGD002704 Spastic Paraplegia, Hereditary Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0038220 BXGD002740 Status Epilepticus Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0038354 BXGD002746 Stomach Diseases Digestive System Diseases
C0038356 BXGD002747 Stomach Neoplasms Digestive System Diseases; Neoplasms
C0038443 BXGD002757 Stress, Psychological Behavior and Behavior Mechanisms
C0038454 BXGD002760 Cerebrovascular accident Nervous System Diseases; Cardiovascular Diseases
C0038525 BXGD002768 Subarachnoid Hemorrhage Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0039101 BXGD002790 synovial sarcoma Neoplasms
C0039483 BXGD002813 Giant Cell Arteritis Skin and Connective Tissue Diseases; Immune System Diseases; Nervous System Diseases; Cardiovascular Diseases
C0040021 BXGD002834 Thromboangiitis Obliterans Cardiovascular Diseases
C0040136 BXGD002845 Thyroid Neoplasm Neoplasms; Endocrine System Diseases
C0040997 BXGD002894 Trigeminal Neuralgia Nervous System Diseases; Stomatognathic Diseases
C0041296 BXGD002903 Tuberculosis Infections
C0041956 BXGD002942 Ureteral obstruction Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0042384 BXGD002979 Vasculitis Cardiovascular Diseases
C0042769 BXGD002999 Virus Diseases Infections
C0043346 BXGD003043 Xeroderma Pigmentosum Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases
C0079298 BXGD003073 Epidermolysis Bullosa Simplex Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C0079588 BXGD003084 Ichthyosis, X-Linked Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases
C0079731 BXGD003087 B-Cell Lymphomas Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0079772 BXGD003099 T-Cell Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0085129 BXGD003128 Bronchial Hyperreactivity Respiratory Tract Diseases
C0085207 BXGD003140 Gestational Diabetes Nutritional and Metabolic Diseases; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0086196 BXGD003269 Eczema, Infantile Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases; Immune System Diseases
C0149516 BXGD003324 Chronic sinusitis Infections; Respiratory Tract Diseases; Otorhinolaryngologic Diseases
C0149678 BXGD003346 Epstein-Barr Virus Infections Infections
C0149721 BXGD003349 Left Ventricular Hypertrophy Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0149782 BXGD003365 Squamous cell carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0149925 BXGD003387 Small cell carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0151650 BXGD003454 Renal fibrosis Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0151718 BXGD003464 Hypocholesterolemia Nutritional and Metabolic Diseases
C0151846 BXGD003485 Periosteal Disorder Musculoskeletal Diseases
C0152013 BXGD003516 Adenocarcinoma of lung (disorder) Neoplasms
C0152018 BXGD003518 Esophageal carcinoma Digestive System Diseases; Neoplasms
C0152020 BXGD003519 Gastroparesis Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0153381 BXGD003626 Malignant neoplasm of mouth Neoplasms; Stomatognathic Diseases
C0153452 BXGD003647 Malignant neoplasm of gallbladder Digestive System Diseases; Neoplasms
C0153676 BXGD003679 Secondary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0155626 BXGD003806 Acute myocardial infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0156149 BXGD003839 Gastrointestinal tract vascular insufficiency Digestive System Diseases
C0162309 BXGD003934 Adrenoleukodystrophy Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases; Endocrine System Diseases
C0162557 BXGD003956 Liver Failure, Acute Digestive System Diseases
C0162770 BXGD003980 Right Ventricular Hypertrophy Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0162871 BXGD003996 Aortic Aneurysm, Abdominal Cardiovascular Diseases
C0175754 BXGD004015 Agenesis of corpus callosum Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0178782 BXGD004034 Orofacial Pain Pathological Conditions, Signs and Symptoms
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0206180 BXGD004170 Ki-1+ Anaplastic Large Cell Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0206655 BXGD004218 Alveolar rhabdomyosarcoma Neoplasms
C0206656 BXGD004219 Embryonal Rhabdomyosarcoma Neoplasms
C0206698 BXGD004248 Cholangiocarcinoma Neoplasms
C0220611 BXGD004295 Childhood Rhabdomyosarcoma Neoplasms
C0220630 BXGD004302 Adult Liver Carcinoma Digestive System Diseases; Neoplasms
C0220641 BXGD004305 Lip and Oral Cavity Carcinoma Neoplasms; Stomatognathic Diseases
C0220668 BXGD004317 Congenital contractural arachnodactyly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0221023 BXGD004369 Cyclic neutropenia Hemic and Lymphatic Diseases
C0221391 BXGD004456 Melanosis coli Pathological Conditions, Signs and Symptoms; Digestive System Diseases; Skin and Connective Tissue Diseases
C0233794 BXGD004618 Memory impairment Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
C0235782 BXGD004769 Gallbladder Carcinoma Digestive System Diseases; Neoplasms
C0235974 BXGD004796 Pancreatic carcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0235989 BXGD004801 Renal interstitial fibrosis Female Urogenital Diseases and Pregnancy Complications; Skin and Connective Tissue Diseases; Male Urogenital Diseases
C0236642 BXGD004815 Pick Disease of the Brain Nervous System Diseases; Mental Disorders
C0238421 BXGD004928 Selenium deficiency
C0238463 BXGD004938 Papillary thyroid carcinoma Neoplasms; Endocrine System Diseases
C0238790 BXGD004956 bone destruction
C0239946 BXGD005010 Fibrosis, Liver Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0242172 BXGD005138 Pelvic Inflammatory Disease Female Urogenital Diseases and Pregnancy Complications; Infections
C0242350 BXGD005154 Erectile dysfunction Male Urogenital Diseases; Mental Disorders
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0242383 BXGD005160 Age related macular degeneration Eye Diseases
C0242422 BXGD005163 Parkinsonian Disorders Nervous System Diseases
C0243026 BXGD005210 Sepsis Pathological Conditions, Signs and Symptoms; Infections
C0263420 BXGD005303 Hyperkeratosis lenticularis perstans Skin and Connective Tissue Diseases
C0263630 BXGD005335 Hypertrophic disorder of skin, unspecified Skin and Connective Tissue Diseases
C0264716 BXGD005417 Chronic heart failure Cardiovascular Diseases
C0264886 BXGD005432 Conduction disorder of the heart Cardiovascular Diseases
C0265219 BXGD005468 Miller Dieker syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0266526 BXGD005687 Norrie disease Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Nervous System Diseases
C0267797 BXGD005777 Acute hepatitis Digestive System Diseases
C0267952 BXGD005794 Fibrosis of pancreas Digestive System Diseases
C0268398 BXGD005933 Familial lichen amyloidosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases
C0271160 BXGD006166 Cortical cataract Eye Diseases
C0271650 BXGD006227 Impaired glucose tolerance Nutritional and Metabolic Diseases
C0272302 BXGD006340 Gray Platelet Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0276447 BXGD006425 Rhinovirus infection Infections
C0276496 BXGD006426 Familial Alzheimer Disease (FAD) Nervous System Diseases; Mental Disorders
C0276501 BXGD006427 Human immunodeficiency virus II infection Female Urogenital Diseases and Pregnancy Complications; Infections; Male Urogenital Diseases; Immune System Diseases
C0276680 BXGD006443 Infection by Candida albicans Infections
C0278510 BXGD006526 Childhood Medulloblastoma Neoplasms
C0278595 BXGD006545 Adult Fibrosarcoma Neoplasms
C0278660 BXGD006555 Adult Synovial Sarcoma Neoplasms
C0278876 BXGD006607 Adult Medulloblastoma Neoplasms
C0278878 BXGD006609 Adult Glioblastoma Neoplasms
C0278996 BXGD006621 Malignant Head and Neck Neoplasm Neoplasms
C0279000 BXGD006622 Liver and Intrahepatic Biliary Tract Carcinoma Digestive System Diseases; Neoplasms
C0279550 BXGD006635 Adult Rhabdomyosarcoma Neoplasms
C0279626 BXGD006657 Squamous cell carcinoma of esophagus Digestive System Diseases; Neoplasms
C0279680 BXGD006680 Transitional cell carcinoma of bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0279702 BXGD006685 Conventional (Clear Cell) Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0279982 BXGD006702 Childhood Synovial Sarcoma Neoplasms
C0280321 BXGD006739 Squamous cell carcinoma of the hypopharynx
C0280449 BXGD006746 secondary acute myeloid leukemia Neoplasms
C0280474 BXGD006748 Childhood Glioblastoma Neoplasms
C0280781 BXGD006758 Adult Pilocytic Astrocytoma Neoplasms
C0281361 BXGD006774 Adenocarcinoma of pancreas Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0281658 BXGD006778 Intraocular Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0281773 BXGD006780 Acute glaucoma
C0282160 BXGD006797 Aplasia Cutis Congenita Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C0282193 BXGD006798 Iron Overload Nutritional and Metabolic Diseases
C0282313 BXGD006803 Condition, Preneoplastic Neoplasms
C0282488 BXGD006804 Interstitial Cystitis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0302592 BXGD006851 Cervix carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0333463 BXGD006954 Senile Plaques Pathological Conditions, Signs and Symptoms
C0333516 BXGD006957 Tumor necrosis Pathological Conditions, Signs and Symptoms
C0334359 BXGD007044 Papillary serous cystadenocarcinoma Neoplasms
C0334583 BXGD007124 Pilocytic Astrocytoma Neoplasms
C0334634 BXGD007144 Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0338106 BXGD007167 Adenocarcinoma of colon Digestive System Diseases; Neoplasms
C0338451 BXGD007176 Frontotemporal dementia Nutritional and Metabolic Diseases; Nervous System Diseases; Mental Disorders
C0338656 BXGD007211 Impaired cognition Mental Disorders
C0340803 BXGD007366 Capillary malformation (disorder) Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0341439 BXGD007408 Chronic liver disease Digestive System Diseases
C0342335 BXGD007461 insulin resistance in diabetes Nutritional and Metabolic Diseases
C0342384 BXGD007470 Idiopathic hypogonadotropic hypogonadism Endocrine System Diseases
C0342418 BXGD007478 Hypothalamic hamartomas Neoplasms; Nervous System Diseases
C0344315 BXGD007666 Depressed mood Behavior and Behavior Mechanisms
C0345904 BXGD007745 Malignant neoplasm of liver Digestive System Diseases; Neoplasms
C0345905 BXGD007746 Intrahepatic Cholangiocarcinoma Neoplasms
C0346388 BXGD007819 Malignant melanoma of choroid Neoplasms; Eye Diseases
C0346647 BXGD007832 Malignant neoplasm of pancreas Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0362046 BXGD007959 Prediabetes syndrome Nutritional and Metabolic Diseases; Endocrine System Diseases
C0375023 BXGD007970 Respiratory syncytial virus (RSV) infection in conditions classified elsewhere and of unspecified site
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0392525 BXGD008052 Nephrolithiasis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0393786 BXGD008144 Trigeminal Neuralgia, Idiopathic Nervous System Diseases; Stomatognathic Diseases
C0393787 BXGD008145 Secondary Trigeminal Neuralgia Nervous System Diseases; Stomatognathic Diseases
C0398650 BXGD008212 Immune thrombocytopenic purpura Pathological Conditions, Signs and Symptoms; Immune System Diseases; Hemic and Lymphatic Diseases
C0399440 BXGD008244 Hereditary gingival fibromatosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Stomatognathic Diseases
C0400966 BXGD008266 Non-alcoholic Fatty Liver Disease Digestive System Diseases
C0406557 BXGD008349 Poikiloderma of Kindler Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases; Stomatognathic Diseases
C0409959 BXGD008400 Osteoarthritis, Knee Musculoskeletal Diseases
C0410158 BXGD008408 Muscle damage
C0424295 BXGD008524 Hyperactive behavior Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0458219 BXGD008903 Complex Regional Pain Syndromes Nervous System Diseases
C0458247 BXGD008904 Allodynia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0476089 BXGD008977 Endometrial Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0519030 BXGD009078 Pneumonia due to Klebsiella pneumoniae Infections; Respiratory Tract Diseases
C0520459 BXGD009084 Necrotizing Enterocolitis Digestive System Diseases
C0521158 BXGD009130 Recurrent tumor
C0524620 BXGD009236 Metabolic Syndrome X Nutritional and Metabolic Diseases
C0524851 BXGD009246 Neurodegenerative Disorders Nervous System Diseases
C0542476 BXGD009276 Forgetful Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0546837 BXGD009343 Malignant neoplasm of esophagus Digestive System Diseases; Neoplasms
C0549473 BXGD009384 Thyroid carcinoma Neoplasms; Endocrine System Diseases
C0553580 BXGD009399 Ewings sarcoma Neoplasms
C0553723 BXGD009416 Squamous cell carcinoma of skin Neoplasms; Skin and Connective Tissue Diseases
C0555198 BXGD009432 Malignant Glioma Neoplasms
C0585442 BXGD009593 Osteosarcoma of bone Neoplasms
C0595921 BXGD009626 Intraocular pressure disorder Eye Diseases
C0595989 BXGD009632 Carcinoma of larynx Neoplasms; Respiratory Tract Diseases; Otorhinolaryngologic Diseases
C0596240 BXGD009638 Cancer Pain Pathological Conditions, Signs and Symptoms
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0598608 BXGD009668 Hyperhomocysteinemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0598935 BXGD009674 Tumor Initiation Pathological Conditions, Signs and Symptoms; Neoplasms
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0677886 BXGD009734 Epithelial ovarian cancer Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0685938 BXGD009829 Malignant neoplasm of gastrointestinal tract Digestive System Diseases; Neoplasms
C0686619 BXGD009835 Secondary malignant neoplasm of lymph node Pathological Conditions, Signs and Symptoms; Neoplasms
C0699790 BXGD009866 Colon Carcinoma Digestive System Diseases; Neoplasms
C0699791 BXGD009867 Stomach Carcinoma Digestive System Diseases; Neoplasms
C0699885 BXGD009869 Carcinoma of bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0700095 BXGD009875 Central neuroblastoma Neoplasms; Nervous System Diseases
C0702166 BXGD009912 Acne Skin and Connective Tissue Diseases
C0730328 BXGD009959 Central Serous Chorioretinopathy Eye Diseases
C0740391 BXGD009987 Middle Cerebral Artery Occlusion Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0740447 BXGD009998 Diabetic peripheral neuropathy Nervous System Diseases; Endocrine System Diseases
C0740457 BXGD010000 Malignant neoplasm of kidney Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0742343 BXGD010061 Acute Chest Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Respiratory Tract Diseases; Hemic and Lymphatic Diseases
C0747102 BXGD010159 Ovarian failure Endocrine System Diseases
C0751211 BXGD010350 Hyperalgesia, Primary Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0751212 BXGD010351 Hyperalgesia, Secondary Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0751213 BXGD010352 Tactile Allodynia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0751214 BXGD010353 Hyperalgesia, Thermal Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0751295 BXGD010383 Memory Loss Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
C0751606 BXGD010523 Adult Acute Lymphocytic Leukemia
C0751690 BXGD010553 Malignant Peripheral Nerve Sheath Tumor Neoplasms; Nervous System Diseases
C0751748 BXGD010573 Nonketotic Hyperglycinemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C0752304 BXGD010711 Hypoxic-Ischemic Encephalopathy Nervous System Diseases; Cardiovascular Diseases
C0752351 BXGD010723 Embryo Loss Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications
C0796195 BXGD010811 Waisman syndrome Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0848558 BXGD010882 Hypospadias Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0853897 BXGD010985 Diabetic Cardiomyopathies Endocrine System Diseases; Cardiovascular Diseases
C0854094 BXGD010998 HIV-2 infection Infections; Immune System Diseases
C0854530 BXGD011023 Infection by human herpesvirus 6 Infections
C0856169 BXGD011096 Endothelial dysfunction
C0860659 BXGD011240 Aloof
C0878500 BXGD011365 Intraepithelial Neoplasia Neoplasms
C0878544 BXGD011368 Cardiomyopathies Cardiovascular Diseases
C0917799 BXGD011410 Hypersomnia Nervous System Diseases; Mental Disorders
C0919267 BXGD011426 ovarian neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0936223 BXGD011477 Metastatic Prostate Carcinoma Neoplasms; Male Urogenital Diseases
C0948008 BXGD011499 Ischemic stroke Nervous System Diseases; Cardiovascular Diseases
C0948089 BXGD011504 Acute Coronary Syndrome Cardiovascular Diseases
C0949664 BXGD011583 Tauopathies Nervous System Diseases
C1134719 BXGD011688 Invasive Ductal Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C1140680 BXGD011718 Malignant neoplasm of ovary Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1168401 BXGD011792 Squamous cell carcinoma of the head and neck Neoplasms
C1176475 BXGD011798 Ductal Carcinoma Neoplasms
C1257958 BXGD011816 Glucose Metabolism Disorders Nutritional and Metabolic Diseases
C1260899 BXGD011841 Anemia, Diamond-Blackfan Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C1261473 BXGD011855 Sarcoma Neoplasms
C1262148 BXGD011873 Grip strength decreased
C1266025 BXGD011935 Traditional Serrated Adenoma Neoplasms
C1266050 BXGD011945 Poorly Differentiated Thyroid Carcinoma Neoplasms; Endocrine System Diseases
C1269683 BXGD012001 Major Depressive Disorder Mental Disorders
C1269955 BXGD012005 Tumor Cell Invasion
C1275122 BXGD012060 Familial multiple trichoepitheliomata Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Skin and Connective Tissue Diseases
C1282496 BXGD012147 Metastasis from malignant tumor of prostate
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C1318485 BXGD012394 Liver regeneration disorder Digestive System Diseases
C1327920 BXGD012457 Childhood Chronic Myelogenous Leukemia, BCR-ABL1 Positive Neoplasms; Hemic and Lymphatic Diseases
C1328407 BXGD012465 Hip Dysplasia Musculoskeletal Diseases; Wounds and Injuries
C1328504 BXGD012469 Hormone refractory prostate cancer Neoplasms; Male Urogenital Diseases
C1332182 BXGD012495 Adult Anaplastic Large Cell Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1332206 BXGD012504 Adult Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1332309 BXGD012521 Anti-Basement Membrane Glomerulonephritis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1332942 BXGD012558 Childhood Anaplastic Large Cell Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1332977 BXGD012569 Childhood Leukemia Neoplasms
C1332979 BXGD012571 Childhood Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1332986 BXGD012574 Childhood Osteosarcoma Neoplasms
C1332995 BXGD012575 Childhood Pilocytic Astrocytoma Neoplasms
C1378703 BXGD012933 Renal carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1397307 BXGD012996 Cardiac fibrosis
C1442837 BXGD013060 Myocardial necrosis Cardiovascular Diseases
C1449563 BXGD013086 Cardiomyopathy, Familial Idiopathic Cardiovascular Diseases
C1458155 BXGD013136 Mammary Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C1512409 BXGD013188 Hepatocarcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C1519670 BXGD013241 Tumor Angiogenesis Pathological Conditions, Signs and Symptoms
C1519689 BXGD013245 Tumor Promotion Pathological Conditions, Signs and Symptoms; Neoplasms
C1527336 BXGD013271 Sjogren's Syndrome Eye Diseases; Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases; Stomatognathic Diseases
C1527390 BXGD013285 Neoplasms, Intracranial Neoplasms; Nervous System Diseases
C1608408 BXGD013434 Malignant transformation
C1621958 BXGD013468 Glioblastoma Multiforme Neoplasms
C1691215 BXGD013491 Penile hypospadias Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1701940 BXGD013526 Pneumonia, Ventilator-Associated Pathological Conditions, Signs and Symptoms; Infections; Respiratory Tract Diseases
C1707446 BXGD013587 Columnar Cell Hyperplasia of the Breast
C1708349 BXGD013597 Hereditary Diffuse Gastric Cancer Digestive System Diseases; Neoplasms
C1800706 BXGD013755 Idiopathic Pulmonary Fibrosis Respiratory Tract Diseases
C1832586 BXGD013854 DERMATITIS HERPETIFORMIS, FAMILIAL Skin and Connective Tissue Diseases; Immune System Diseases
C1832661 BXGD013866 ANOPHTHALMIA AND PULMONARY HYPOPLASIA Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Respiratory Tract Diseases
C1841972 BXGD014484 Glucocorticoid Receptor Deficiency Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C1848296 BXGD014918 DOSAGE-SENSITIVE SEX REVERSAL Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C1855038 BXGD015452 Hepatocellular necrosis
C1855739 BXGD015538 Indifference to Pain, Congenital, Autosomal Recessive Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C1863844 BXGD016200 Adult-onset citrullinemia type 2 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C1956346 BXGD016627 Coronary Artery Disease Cardiovascular Diseases
C1959589 BXGD016641 Angioma, Cavernous Neoplasms; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C1960398 BXGD016658 HER2-positive carcinoma of breast Neoplasms; Skin and Connective Tissue Diseases
C1961099 BXGD016672 Precursor T-Cell Lymphoblastic Leukemia-Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1969372 BXGD016775 Tubulointerstitial fibrosis
C2004435 BXGD016871 Vascular insufficiency of intestine Digestive System Diseases; Cardiovascular Diseases
C2020625 BXGD016882 Group B Streptococcal Infection Infections
C2062441 BXGD016897 Influenza A
C2118460 BXGD016927 Acute colitis Digestive System Diseases
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2347748 BXGD017041 Adult Erythroleukemia
C2347761 BXGD017049 Childhood Myelodysplastic Syndrome Hemic and Lymphatic Diseases
C2363741 BXGD017100 HIV-1 infection
C2363866 BXGD017110 Traumatic occlusion
C2711227 BXGD017478 Steatohepatitis Digestive System Diseases
C2717836 BXGD017510 Steroid Sulfatase Deficiency Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases
C2745900 BXGD017568 Promyelocytic leukemia
C2750440 BXGD017660 FATTY LIVER DISEASE, NONALCOHOLIC, SUSCEPTIBILITY TO, 1
C2750441 BXGD017661 LIVER DISEASE, ALCOHOLIC, SUSCEPTIBILITY TO, 1
C2931822 BXGD018068 Nasopharyngeal carcinoma Neoplasms; Stomatognathic Diseases; Otorhinolaryngologic Diseases
C2936719 BXGD018130 Mechanical Allodynia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C2939419 BXGD018178 Secondary Neoplasm Pathological Conditions, Signs and Symptoms; Neoplasms
C3150651 BXGD018316 FATTY LIVER DISEASE, NONALCOHOLIC, SUSCEPTIBILITY TO, 2
C3241937 BXGD018578 Nonalcoholic Steatohepatitis Digestive System Diseases
C3463824 BXGD018899 MYELODYSPLASTIC SYNDROME Hemic and Lymphatic Diseases
C3469521 BXGD018910 FANCONI ANEMIA, COMPLEMENTATION GROUP A (disorder) Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Hemic and Lymphatic Diseases
C3469526 BXGD018914 FANCONI ANEMIA, COMPLEMENTATION GROUP F Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Hemic and Lymphatic Diseases
C3489791 BXGD018949 Parkinson Disease, Familial, Type 1 Nervous System Diseases
C3539878 BXGD019087 Triple Negative Breast Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C3696954 BXGD019349 Precapillary pulmonary hypertension Respiratory Tract Diseases
C3714636 BXGD019421 Pneumonitis Infections; Respiratory Tract Diseases
C3714948 BXGD019440 PACHYONYCHIA CONGENITA 3
C3826634 BXGD019731 Bronchitis in children
C3828416 BXGD019740 Radiation Damage Wounds and Injuries
C3887461 BXGD019876 Head and Neck Carcinoma Neoplasms
C3887709 BXGD019918 Optic Neuropathy Eye Diseases; Nervous System Diseases
C3888194 BXGD019955 MIXED LINEAGE LEUKEMIA
C3900098 BXGD020106 Adult Myelodysplastic Syndrome Hemic and Lymphatic Diseases
C4020732 BXGD020474 Mitochondrial abnormalities
C4048328 BXGD021903 cervical cancer Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C4048329 BXGD021904 Immunosuppression
C4054188 BXGD021977 Ph-Like Acute Lymphoblastic Leukemia
C4082937 BXGD022095 Necrotizing enterocolitis in fetus OR newborn Digestive System Diseases
C4083008 BXGD022100 Guillain-Barre Syndrome, Familial Immune System Diseases; Nervous System Diseases
C4086152 BXGD022123 Childhood Astrocytoma Neoplasms
C4086165 BXGD022126 Childhood Neuroblastoma Neoplasms
C4511452 BXGD023002 Sporadic Parkinson disease Nervous System Diseases
C4520840 BXGD023041 Erythroleukemia (Erythroid/Myeloid) Neoplasms; Hemic and Lymphatic Diseases
C4524092 BXGD023092 Chronic rhinosinusitis with nasal polyps
C4525297 BXGD023131 Stage 0 Gallbladder Cancer AJCC v8
C4525300 BXGD023132 Stage IIA Gallbladder Cancer AJCC v8
C4525301 BXGD023133 Stage IIB Gallbladder Cancer AJCC v8
C4525302 BXGD023134 Stage III Gallbladder Cancer AJCC v8
C4525305 BXGD023135 Stage IV Gallbladder Cancer AJCC v8
C4529962 BXGD023178 Fatty Liver Disease
C4551649 BXGD023382 Congenital Dysplasia Of The Hip Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C4551683 BXGD023389 Adrenal Gland Pheochromocytoma Neoplasms; Endocrine System Diseases
C4551686 BXGD023391 Malignant neoplasm of soft tissue Neoplasms
C4721414 BXGD023738 Mantle cell lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C4721610 BXGD023760 Carcinoma, Ovarian Epithelial Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C4722085 BXGD023788 Malignant neoplasm of colon and/or rectum
C4722518 BXGD023806 Triple-Negative Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C4733095 BXGD023910 HER2-negative breast cancer
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0000655 Harmalol 200.24
BXGC0001544 Harmaline 214.26
BXGC0001545 Harmine 212.25
BXGC0001962 Hesperetin 302.28
BXGC0002043 Acacetin 284.26
BXGC0002071 Apigenin 270.24
BXGC0002094 Rhamnetin 316.26
BXGC0002588 Magnesium 24.31
BXGC0002605 Adenosine 267.24
BXGC0003705 Chloride 35.45
BXGC0003857 Cyanidin 3-rutinoside 595.53
BXGC0004580 Carbanilide 212.25
BXGC0004705 Diphenylamine 169.22
BXGC0005678 Quercetagetin 318.24
BXGC0005683 Quercetin 302.24
BXGC0006956 (+)-alpha-Pinene 136.23
BXGC0007014 Harman 182.22
BXGC0007029 Emodin 270.24
BXGC0008747 Tamarixetin 316.26
BXGC0011627 Glycyrrhetic acid 470.69
BXGC0012352 Chelerythrine 348.12
BXGC0018661 Isobicyclogermacral 218.17
BXGC0023872 Adenine 135.05
BXGC0024554 D-luciferin 280
BXGC0028696 Cichoric Acid 474.08
BXGC0029810 1,5-Bis(4-Hydroxy-3-Methoxyphenyl)-1,4-Pentadien-3-One 326.12
BXGC0031622 Podofilox 414.13
BXGC0032115 (-)-alpha-Pinene 136.13
BXGC0033607 1(10)-Aristolene-5-one 218.17
BXGC0034256 Rottlerin 516.18
BXGC0036201 D-Epigalbacin 340.13
BXGC0042376 Picropodophyllotoxin 414.13
BXGC0044857 Sp-600125 220.06
BXGC0045254 Sb-202190 331.11
BXGC0047692 Gefitinib 446.15
BXGC0050099 (2E,5S,6S,8Z,11S)-5,6,15-Trihydroxy-17-Methoxy-11-Methyl-12-Oxabicyclo[12.4.0]Octadeca-1(14),2,8,15,17-Pentaene-7,13-Dione 362.14
BXGC0051873 Sl-0101 516.13
BXGC0052109 Cardamomin 270.09
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein