Showing entry for Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT010499
Protein NamePhosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform
Uniport IdP46020
GenePHKA1
Gene Id5255
DomainGlyco_hydro_15
Pfam PF00723  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
3. Environmental Information Processing 3.2 Signal transduction hsa04020 Calcium signaling pathway
5. Organismal Systems 5.2 Endocrine system hsa04910 Insulin signaling pathway
5. Organismal Systems 5.2 Endocrine system hsa04922 Glucagon signaling pathway
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006091 generation of precursor metabolites and energy
Biological Process GO:0005980 glycogen catabolic process
Biological Process GO:0005977 glycogen metabolic process
molecular function GO:0005516 calmodulin binding
molecular function GO:0004689 phosphorylase kinase activity
cellular component GO:0005829 cytosol
cellular component GO:0005964 phosphorylase kinase complex
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
R-HSA-1430728 Metabolism
R-HSA-1430728 Metabolism
R-HSA-70221 Glycogen breakdown (glycogenolysis)
R-HSA-70221 Glycogen breakdown (glycogenolysis)
R-HSA-71387 Metabolism of carbohydrates
R-HSA-71387 Metabolism of carbohydrates
R-HSA-8982491 Glycogen metabolism
R-HSA-8982491 Glycogen metabolism
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0011853 BXGD000752 Diabetes Mellitus, Experimental Nutritional and Metabolic Diseases; Endocrine System Diseases
C0017919 BXGD001150 Glycogen Storage Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0017927 BXGD001158 Glycogen Storage Disease Type VIII Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0020676 BXGD001462 Hypothyroidism Endocrine System Diseases
C0026848 BXGD001941 Myopathy Musculoskeletal Diseases; Nervous System Diseases
C0151786 BXGD003475 Muscle Weakness Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases
C0241005 BXGD005072 Creatine phosphokinase serum increased
C0268147 BXGD005837 Glycogen storage disease, type IX Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0424551 BXGD008533 Impaired exercise tolerance
C0541794 BXGD009262 Skeletal muscle atrophy
C1845151 BXGD014719 Glycogen Storage Disease, Type IXD Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C1845155 BXGD014720 Exercise-induced myoglobinuria Musculoskeletal Diseases
C1845977 BXGD014769 X- linked recessive
C1850830 BXGD015181 Exercise-induced myalgia Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases
C1855579 BXGD015514 Exercise-induced muscle stiffness
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0024554 D-luciferin 280
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein