Showing entry for Solute carrier organic anion transporter family member 1A2


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT010536
Protein NameSolute carrier organic anion transporter family member 1A2
Uniport IdP46721
GeneSLCO1A2
Gene Id6579
DomainKazal_2; OATP
Pfam PF07648   PF03137  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
5. Organismal Systems 5.4 Digestive system hsa04976 Bile secretion
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0015721 bile acid and bile salt transport
Biological Process GO:0015711 organic anion transport
Biological Process GO:0043252 sodium-independent organic anion transport
molecular function GO:0015125 bile acid transmembrane transporter activity
molecular function GO:0008514 organic anion transmembrane transporter activity
molecular function GO:0015347 sodium-independent organic anion transmembrane transporter activity
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
R-HSA-1430728 Metabolism
R-HSA-159418 Recycling of bile acids and salts
R-HSA-194068 Bile acid and bile salt metabolism
R-HSA-382551 Transport of small molecules
R-HSA-425397 Transport of vitamins, nucleosides, and related molecules
R-HSA-425407 SLC-mediated transmembrane transport
R-HSA-556833 Metabolism of lipids
R-HSA-879518 Transport of organic anions
R-HSA-8957322 Metabolism of steroids
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0002895 BXGD000152 Anemia, Sickle Cell Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0006118 BXGD000372 Brain Neoplasms Neoplasms; Nervous System Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007097 BXGD000424 Carcinoma Neoplasms
C0008350 BXGD000531 Cholelithiasis Digestive System Diseases
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0014544 BXGD000926 Epilepsy Nervous System Diseases
C0018790 BXGD001221 Cardiac Arrest Cardiovascular Diseases
C0019196 BXGD001301 Hepatitis C Digestive System Diseases; Infections
C0020433 BXGD001379 Hyperbilirubinemia Pathological Conditions, Signs and Symptoms
C0023449 BXGD001650 Acute lymphocytic leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023452 BXGD001651 Childhood Acute Lymphoblastic Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023473 BXGD001661 Myeloid Leukemia, Chronic Neoplasms; Hemic and Lymphatic Diseases
C0024537 BXGD001786 Malaria, Vivax Infections
C0027651 BXGD002009 Neoplasms Neoplasms
C0038868 BXGD002781 Progressive supranuclear palsy Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C0042769 BXGD002999 Virus Diseases Infections
C0085293 BXGD003154 Hepatitis E Digestive System Diseases; Infections
C0086237 BXGD003273 Epilepsy, Cryptogenic Nervous System Diseases
C0149931 BXGD003388 Migraine Disorders Nervous System Diseases
C0236018 BXGD004804 Aura Nervous System Diseases
C0268318 BXGD005896 Cholestasis of pregnancy Digestive System Diseases; Female Urogenital Diseases and Pregnancy Complications
C0279584 BXGD006641 Childhood B Acute Lymphoblastic Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0344395 BXGD007668 Bilirubin measurement
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0524620 BXGD009236 Metabolic Syndrome X Nutritional and Metabolic Diseases
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0746883 BXGD010153 Febrile Neutropenia Hemic and Lymphatic Diseases
C0751111 BXGD010319 Awakening Epilepsy Nervous System Diseases
C0751606 BXGD010523 Adult Acute Lymphocytic Leukemia
C0947622 BXGD011493 Cholecystolithiasis Digestive System Diseases
C0948008 BXGD011499 Ischemic stroke Nervous System Diseases; Cardiovascular Diseases
C1168401 BXGD011792 Squamous cell carcinoma of the head and neck Neoplasms
C1287365 BXGD012174 Bilirubin level result
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1458155 BXGD013136 Mammary Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C1961102 BXGD016673 Precursor Cell Lymphoblastic Leukemia Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C2985280 BXGD018223 Blood Protein Measurement
C3241937 BXGD018578 Nonalcoholic Steatohepatitis Digestive System Diseases
C4529962 BXGD023178 Fatty Liver Disease
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0005654 Naringin 580.53
BXGC0022231 Ursodiol 392.29
BXGC0022544 Digoxin 780.43
BXGC0025513 Sid73376 872.4
BXGC0025862 Levothyroxine 776.69
BXGC0026391 Naloxone 327.15
BXGC0026595 Glycyrrhizin 822.4
BXGC0035201 Quinidine 324.18
BXGC0044017 Verapamil 454.28
BXGC0051524 Ouabain 584.28
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein