Showing entry for Metabotropic glutamate receptor 8


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT010580
Protein NameMetabotropic glutamate receptor 8
Uniport IdP47743
GeneGrm8
Gene Id14823
Domain7tm_3; ANF_receptor; NCD3G
Pfam PF00003   PF01094   PF07562  
OrganismMus musculus (Mouse)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007196 adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway
Biological Process GO:0007193 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway
Biological Process GO:0007268 chemical synaptic transmission
Biological Process GO:0050966 detection of mechanical stimulus involved in sensory perception of pain
Biological Process GO:0007216 G protein-coupled glutamate receptor signaling pathway
Biological Process GO:0046928 regulation of neurotransmitter secretion
Biological Process GO:0051966 regulation of synaptic transmission, glutamatergic
Biological Process GO:2000300 regulation of synaptic vesicle exocytosis
Biological Process GO:0035249 synaptic transmission, glutamatergic
molecular function GO:0008066 glutamate receptor activity
molecular function GO:0004930 G protein-coupled receptor activity
molecular function GO:0001642 group III metabotropic glutamate receptor activity
cellular component GO:0098982 GABA-ergic synapse
cellular component GO:0098978 glutamatergic synapse
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0099059 integral component of presynaptic active zone membrane
cellular component GO:0043025 neuronal cell body
cellular component GO:0043005 neuron projection
cellular component GO:0042734 presynaptic membrane
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0006162 L-Glutamic acid 147.13
BXGC0036441 Quisqualate 189.04
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein