Showing entry for Angiotensin-converting enzyme


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT010588
Protein NameAngiotensin-converting enzyme
Uniport IdP47820
GeneAce
Gene Id24310
DomainPeptidase_M2
Pfam PF01401  
OrganismRattus norvegicus (Rat)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007568 aging
Biological Process GO:0050435 amyloid-beta metabolic process
Biological Process GO:0060978 angiogenesis involved in coronary vascular morphogenesis
Biological Process GO:0031100 animal organ regeneration
Biological Process GO:0050482 arachidonic acid secretion
Biological Process GO:0010815 bradykinin catabolic process
Biological Process GO:0007420 brain development
Biological Process GO:0071838 cell proliferation in bone marrow
Biological Process GO:1904045 cellular response to aldosterone
Biological Process GO:0071333 cellular response to glucose stimulus
Biological Process GO:0042755 eating behavior
Biological Process GO:0009792 embryo development ending in birth or egg hatching
Biological Process GO:0007565 female pregnancy
Biological Process GO:0060047 heart contraction
Biological Process GO:0042447 hormone catabolic process
Biological Process GO:0001822 kidney development
Biological Process GO:0048286 lung alveolus development
Biological Process GO:0030324 lung development
Biological Process GO:0008584 male gonad development
Biological Process GO:0097756 negative regulation of blood vessel diameter
Biological Process GO:0090281 negative regulation of calcium ion import
Biological Process GO:1903597 negative regulation of gap junction assembly
Biological Process GO:0010629 negative regulation of gene expression
Biological Process GO:0046325 negative regulation of glucose import
Biological Process GO:0032091 negative regulation of protein binding
Biological Process GO:0035814 negative regulation of renal sodium excretion
Biological Process GO:0002446 neutrophil mediated immunity
Biological Process GO:0043171 peptide catabolic process
Biological Process GO:0006518 peptide metabolic process
Biological Process GO:0043065 positive regulation of apoptotic process
Biological Process GO:0045777 positive regulation of blood pressure
Biological Process GO:0050729 positive regulation of inflammatory response
Biological Process GO:0050769 positive regulation of neurogenesis
Biological Process GO:2000170 positive regulation of peptidyl-cysteine S-nitrosylation
Biological Process GO:1900086 positive regulation of peptidyl-tyrosine autophosphorylation
Biological Process GO:0032092 positive regulation of protein binding
Biological Process GO:0061098 positive regulation of protein tyrosine kinase activity
Biological Process GO:0003084 positive regulation of systemic arterial blood pressure
Biological Process GO:0010608 posttranscriptional regulation of gene expression
Biological Process GO:0060177 regulation of angiotensin metabolic process
Biological Process GO:0008217 regulation of blood pressure
Biological Process GO:1902033 regulation of hematopoietic stem cell proliferation
Biological Process GO:0014910 regulation of smooth muscle cell migration
Biological Process GO:0003081 regulation of systemic arterial blood pressure by renin-angiotensin
Biological Process GO:0071548 response to dexamethasone
Biological Process GO:0042493 response to drug
Biological Process GO:0001666 response to hypoxia
Biological Process GO:0034616 response to laminar fluid shear stress
Biological Process GO:0032496 response to lipopolysaccharide
Biological Process GO:0031667 response to nutrient levels
Biological Process GO:0097066 response to thyroid hormone
Biological Process GO:0019233 sensory perception of pain
Biological Process GO:0007283 spermatogenesis
Biological Process GO:0042310 vasoconstriction
molecular function GO:0003779 actin binding
molecular function GO:0031711 bradykinin receptor binding
molecular function GO:0004180 carboxypeptidase activity
molecular function GO:0031404 chloride ion binding
molecular function GO:0008144 drug binding
molecular function GO:0004175 endopeptidase activity
molecular function GO:0008238 exopeptidase activity
molecular function GO:0070573 metallodipeptidase activity
molecular function GO:0008237 metallopeptidase activity
molecular function GO:0051019 mitogen-activated protein kinase binding
molecular function GO:0031434 mitogen-activated protein kinase kinase binding
molecular function GO:0008233 peptidase activity
molecular function GO:0008241 peptidyl-dipeptidase activity
molecular function GO:0008240 tripeptidyl-peptidase activity
molecular function GO:0008270 zinc ion binding
cellular component GO:0009925 basal plasma membrane
cellular component GO:0031526 brush border membrane
cellular component GO:0005737 cytoplasm
cellular component GO:0005768 endosome
cellular component GO:0009897 external side of plasma membrane
cellular component GO:0070062 extracellular exosome
cellular component GO:0005615 extracellular space
cellular component GO:0016021 integral component of membrane
cellular component GO:0005764 lysosome
cellular component GO:0005886 plasma membrane
cellular component GO:0097225 sperm midpiece
cellular component GO:0031982 vesicle
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0008753 Isoquercitrin 464.38
BXGC0008824 Astragalin 448.38
BXGC0014231 Isoquercitin 2''-O-Gallate 616.11
BXGC0048458 Astragalin 2''-O-Gallate 600.11
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein