protein

Showing entry for ATP synthase subunit O, mitochondrial

　　　　　　　　　　　　

General Target Information
BXGT Id	BXGT010609
Protein Name	ATP synthase subunit O, mitochondrial
Uniport Id	P48047
Gene	ATP5PO
Gene Id	539
Domain	OSCP
Pfam	PF00213
Organism	Homo sapiens (Human)

Target protein affiliated biological pathways

KEGG

Class	Subclass	KEGG Id	Pathway Name
1. Metabolism	1.2 Energy metabolism	hsa00190	Oxidative phosphorylation
1. Metabolism	1.0 Global and overview maps	hsa01100	Metabolic pathways
5. Organismal Systems	5.10 Environmental adaptation	hsa04714	Thermogenesis
6. Human Diseases	6.4 Neurodegenerative diseases	hsa05010	Alzheimer disease
6. Human Diseases	6.4 Neurodegenerative diseases	hsa05012	Parkinson disease
6. Human Diseases	6.4 Neurodegenerative diseases	hsa05016	Huntington disease

Gene Ontology

GO Type	GO Id	Gene Ontology
Biological Process	GO:0006754	ATP biosynthetic process
Biological Process	GO:0042407	cristae formation
Biological Process	GO:0042776	mitochondrial ATP synthesis coupled proton transport
Biological Process	GO:1902600	proton transmembrane transport
molecular function	GO:0008144	drug binding
molecular function	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism
cellular component	GO:0005743	mitochondrial inner membrane
cellular component	GO:0005753	mitochondrial proton-transporting ATP synthase complex
cellular component	GO:0005739	mitochondrion
cellular component	GO:0005634	nucleus
cellular component	GO:0005886	plasma membrane

Reactome

Pathway Id	Pathway Name
R-HSA-1428517	The citric acid (TCA) cycle and respiratory electron transport
R-HSA-1430728	Metabolism
R-HSA-1592230	Mitochondrial biogenesis
R-HSA-163200	Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
R-HSA-163210	Formation of ATP by chemiosmotic coupling
R-HSA-1852241	Organelle biogenesis and maintenance
R-HSA-8949613	Cristae formation

Target protein-related diseases

Disease

CUI Id	BXGD Id	Disease Name	Disease Class
C0002395	BXGD000111	Alzheimer's Disease	Nervous System Diseases; Mental Disorders
C0004364	BXGD000270	Autoimmune Diseases	Immune System Diseases
C0011860	BXGD000755	Diabetes Mellitus, Non-Insulin-Dependent	Nutritional and Metabolic Diseases; Endocrine System Diseases
C0016325	BXGD001053	Fluoride Poisoning	Chemically-Induced Disorders
C0020676	BXGD001462	Hypothyroidism	Endocrine System Diseases

Target protein-related compounds

Compounds

BXGC Id	Compound Name	Strcuture	Molecular Weight
BXGC0051100	dihydroartemisinin		284.16

The target protein-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compound^{? Number of compound in food, higher numbers indicate the food are more associated with the protein}