Showing entry for Glycine receptor subunit beta


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT010621
Protein NameGlycine receptor subunit beta
Uniport IdP48167
GeneGLRB
Gene Id2743
DomainNeur_chan_LBD; Neur_chan_memb
Pfam PF02931   PF02932  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
3. Environmental Information Processing 3.3 Signaling molecules and interaction hsa04080 Neuroactive ligand-receptor interaction
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007340 acrosome reaction
Biological Process GO:0007628 adult walking behavior
Biological Process GO:0007268 chemical synaptic transmission
Biological Process GO:1902476 chloride transmembrane transport
Biological Process GO:0097112 gamma-aminobutyric acid receptor clustering
Biological Process GO:0034220 ion transmembrane transport
Biological Process GO:0006811 ion transport
Biological Process GO:0007399 nervous system development
Biological Process GO:0050877 nervous system process
Biological Process GO:0007218 neuropeptide signaling pathway
Biological Process GO:0042391 regulation of membrane potential
Biological Process GO:0043200 response to amino acid
Biological Process GO:0060013 righting reflex
Biological Process GO:0007165 signal transduction
Biological Process GO:0001964 startle response
Biological Process GO:0060012 synaptic transmission, glycinergic
Biological Process GO:0007601 visual perception
molecular function GO:0016934 extracellularly glycine-gated chloride channel activity
molecular function GO:0016933 extracellularly glycine-gated ion channel activity
molecular function GO:0016594 glycine binding
molecular function GO:0030594 neurotransmitter receptor activity
molecular function GO:0044877 protein-containing complex binding
molecular function GO:0004888 transmembrane signaling receptor activity
cellular component GO:0005737 cytoplasm
cellular component GO:0030425 dendrite
cellular component GO:0098982 GABA-ergic synapse
cellular component GO:0016935 glycine-gated chloride channel complex
cellular component GO:0098690 glycinergic synapse
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0043005 neuron projection
cellular component GO:0005886 plasma membrane
cellular component GO:0045211 postsynaptic membrane
cellular component GO:0045202 synapse
Reactome
Pathway Id Pathway Name
R-HSA-112314 Neurotransmitter receptors and postsynaptic signal transmission
R-HSA-112314 Neurotransmitter receptors and postsynaptic signal transmission
R-HSA-112315 Transmission across Chemical Synapses
R-HSA-112315 Transmission across Chemical Synapses
R-HSA-112316 Neuronal System
R-HSA-112316 Neuronal System
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001818 BXGD000080 Agoraphobia Mental Disorders
C0004106 BXGD000254 Astigmatism Eye Diseases
C0004134 BXGD000256 Ataxia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0004352 BXGD000269 Autistic Disorder Mental Disorders
C0014544 BXGD000926 Epilepsy Nervous System Diseases
C0014548 BXGD000928 Epilepsy, Generalized Nervous System Diseases
C0014868 BXGD000965 Esophagitis Digestive System Diseases
C0014877 BXGD000967 Esotropia Eye Diseases; Nervous System Diseases
C0015644 BXGD001008 Muscular fasciculation Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0017168 BXGD001101 Gastroesophageal reflux disease Digestive System Diseases
C0026826 BXGD001935 Muscle Hypertonia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0026837 BXGD001937 Muscle Rigidity Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases
C0026838 BXGD001938 Muscle Spasticity Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases
C0027066 BXGD001966 Myoclonus Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0027092 BXGD001971 Myopia Eye Diseases
C0030319 BXGD002208 Panic Disorder Mental Disorders
C0036572 BXGD002625 Seizures Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0037317 BXGD002689 Sleep disturbances Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0151889 BXGD003498 Hyperreflexia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0162298 BXGD003933 Joint stiffness Musculoskeletal Diseases
C0221170 BXGD004400 Muscular stiffness Nervous System Diseases
C0234166 BXGD004628 Hyperexplexia Nervous System Diseases
C0424605 BXGD008535 Developmental delay (disorder) Mental Disorders
C0477362 BXGD009000 Other specified extrapyramidal and movement disorders
C0557874 BXGD009444 Global developmental delay
C0575081 BXGD009512 Gait abnormality Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0700201 BXGD009880 Dyssomnias Nervous System Diseases; Mental Disorders
C0810364 BXGD010846 Cleft Lip with or without Cleft Palate
C0851578 BXGD010925 Sleep Disorders Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders
C1306503 BXGD012363 Congenital exomphalos Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C1740801 BXGD013744 Exaggerated startle response
C1835614 BXGD014039 Hereditary Hyperexplexia Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases
C3489393 BXGD018928 Hiatal Hernia Pathological Conditions, Signs and Symptoms
C3553291 BXGD019167 HYPEREKPLEXIA 2
C3714756 BXGD019429 Intellectual Disability Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C4084968 BXGD022110 Hereditary Hyperekplexia Immune System Diseases; Nervous System Diseases
C4293678 BXGD022511 Glabellar reflex
C4551915 BXGD023441 Gait Disturbance, CTCAE
C4553743 BXGD023548 Spasticity, CTCAE
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000226 Glycine 75.07
BXGC0017719 Strychnine 334.17
BXGC0038768 2,6-Ditert-Butylphenol 206.17
BXGC0040150 Cannabidiol 314.22
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein