protein

Showing entry for Vitamin D3 receptor

General Target Information
BXGT Id	BXGT010625
Protein Name	Vitamin D3 receptor
Uniport Id	P48281
Gene	Vdr
Gene Id	22337
Domain	Hormone_recep; zf-C4
Pfam	PF00104 PF00105
Organism	Mus musculus (Mouse)

Target protein affiliated biological pathways

KEGG

Class	Subclass	KEGG Id	Pathway Name

Gene Ontology

GO Type	GO Id	Gene Ontology
Biological Process	GO:0009887	animal organ morphogenesis
Biological Process	GO:0097190	apoptotic signaling pathway
Biological Process	GO:0038183	bile acid signaling pathway
Biological Process	GO:0006816	calcium ion transport
Biological Process	GO:0030154	cell differentiation
Biological Process	GO:0000902	cell morphogenesis
Biological Process	GO:0006874	cellular calcium ion homeostasis
Biological Process	GO:0042632	cholesterol homeostasis
Biological Process	GO:0046697	decidualization
Biological Process	GO:0050892	intestinal absorption
Biological Process	GO:0007595	lactation
Biological Process	GO:0055088	lipid homeostasis
Biological Process	GO:0006629	lipid metabolic process
Biological Process	GO:0060745	mammary gland branching involved in pregnancy
Biological Process	GO:0007275	multicellular organism development
Biological Process	GO:0008285	negative regulation of cell population proliferation
Biological Process	GO:0010629	negative regulation of gene expression
Biological Process	GO:0010839	negative regulation of keratinocyte proliferation
Biological Process	GO:0045892	negative regulation of transcription, DNA-templated
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II
Biological Process	GO:0060058	positive regulation of apoptotic process involved in mammary gland involution
Biological Process	GO:0010628	positive regulation of gene expression
Biological Process	GO:0045618	positive regulation of keratinocyte differentiation
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II
Biological Process	GO:0010980	positive regulation of vitamin D 24-hydroxylase activity
Biological Process	GO:0060558	regulation of calcidiol 1-monooxygenase activity
Biological Process	GO:0051924	regulation of calcium ion transport
Biological Process	GO:0006355	regulation of transcription, DNA-templated
Biological Process	GO:0001501	skeletal system development
Biological Process	GO:0070561	vitamin D receptor signaling pathway
molecular function	GO:1902098	calcitriol binding
molecular function	GO:0003677	DNA binding
molecular function	GO:1902121	lithocholic acid binding
molecular function	GO:0038186	lithocholic acid receptor activity
molecular function	GO:0004879	nuclear receptor activity
molecular function	GO:0046965	retinoid X receptor binding
molecular function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding
molecular function	GO:0043565	sequence-specific DNA binding
molecular function	GO:0038023	signaling receptor activity
molecular function	GO:0008134	transcription factor binding
molecular function	GO:0005499	vitamin D binding
molecular function	GO:0070644	vitamin D response element binding
molecular function	GO:0008270	zinc ion binding
cellular component	GO:0005829	cytosol
cellular component	GO:0001651	dense fibrillar component
cellular component	GO:0000791	euchromatin
cellular component	GO:0000792	heterochromatin
cellular component	GO:0043231	intracellular membrane-bounded organelle
cellular component	GO:0005720	nuclear heterochromatin
cellular component	GO:0016363	nuclear matrix
cellular component	GO:0005654	nucleoplasm
cellular component	GO:0005634	nucleus
cellular component	GO:0048471	perinuclear region of cytoplasm
cellular component	GO:0043235	receptor complex
cellular component	GO:0090575	RNA polymerase II transcription regulator complex
cellular component	GO:0030315	T-tubule

Reactome

Pathway Id	Pathway Name

Target protein-related diseases

Disease

CUI Id	BXGD Id	Disease Name	Disease Class

Target protein-related compounds

Compounds

BXGC Id	Compound Name	Strcuture	Molecular Weight
BXGC0004710	3-Hydroxybenzoic acid		138.12
BXGC0012228	Vitamin D		384.64
BXGC0012291	25-Hydroxycholecalciferol		400.64
BXGC0037795	Cyclopamine		411.31
BXGC0042413	Calcitriol		416.33

The target protein-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compound^{? Number of compound in food, higher numbers indicate the food are more associated with the protein}