Showing entry for Potassium voltage-gated channel subfamily C member 1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT010643
Protein NamePotassium voltage-gated channel subfamily C member 1
Uniport IdP48547
GeneKCNC1
Gene Id3746
DomainBTB_2; Ion_trans
Pfam PF02214   PF00520  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0035690 cellular response to drug
Biological Process GO:0021549 cerebellum development
Biological Process GO:0021759 globus pallidus development
Biological Process GO:1903818 positive regulation of voltage-gated potassium channel activity
Biological Process GO:0071805 potassium ion transmembrane transport
Biological Process GO:0006813 potassium ion transport
Biological Process GO:0051260 protein homooligomerization
Biological Process GO:0051262 protein tetramerization
Biological Process GO:0014075 response to amine
Biological Process GO:0010996 response to auditory stimulus
Biological Process GO:0071774 response to fibroblast growth factor
Biological Process GO:0009642 response to light intensity
Biological Process GO:1990089 response to nerve growth factor
Biological Process GO:0035864 response to potassium ion
Biological Process GO:0009636 response to toxic substance
molecular function GO:0005251 delayed rectifier potassium channel activity
molecular function GO:0044325 ion channel binding
molecular function GO:0019894 kinesin binding
molecular function GO:0099508 voltage-gated ion channel activity involved in regulation of presynaptic membrane potential
molecular function GO:0005249 voltage-gated potassium channel activity
cellular component GO:0030673 axolemma
cellular component GO:0030424 axon
cellular component GO:0009986 cell surface
cellular component GO:0032590 dendrite membrane
cellular component GO:0016021 integral component of membrane
cellular component GO:0099056 integral component of presynaptic membrane
cellular component GO:0043025 neuronal cell body
cellular component GO:0032809 neuronal cell body membrane
cellular component GO:0005886 plasma membrane
cellular component GO:0008076 voltage-gated potassium channel complex
Reactome
Pathway Id Pathway Name
R-HSA-112316 Neuronal System
R-HSA-1296071 Potassium Channels
R-HSA-1296072 Voltage gated Potassium channels
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0004134 BXGD000256 Ataxia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0007758 BXGD000475 Cerebellar Ataxia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0013362 BXGD000817 Dysarthria Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0014544 BXGD000926 Epilepsy Nervous System Diseases
C0014550 BXGD000930 Myoclonic Epilepsy Nervous System Diseases
C0015967 BXGD001030 Fever Pathological Conditions, Signs and Symptoms
C0025323 BXGD001864 Menorrhagia Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications
C0027066 BXGD001966 Myoclonus Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0036572 BXGD002625 Seizures Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0040822 BXGD002885 Tremor Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0085584 BXGD003195 Encephalopathies Nervous System Diseases
C0151611 BXGD003447 Electroencephalogram abnormal Nervous System Diseases
C0156404 BXGD003857 Irregular Menstruation Pathological Conditions, Signs and Symptoms
C0234162 BXGD004627 Cerebellar Dysmetria Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0234979 BXGD004707 Dysdiadochokinesis Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0234985 BXGD004708 Mental deterioration Mental Disorders
C0239548 BXGD004984 Fasciculation, Tongue Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0424605 BXGD008535 Developmental delay (disorder) Mental Disorders
C0494475 BXGD009030 Tonic - clonic seizures Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0543888 BXGD009300 Epileptic encephalopathy Nervous System Diseases
C0557874 BXGD009444 Global developmental delay
C0751776 BXGD010585 Atypical Inclusion-Body Disease Nervous System Diseases
C0751777 BXGD010586 Familial Progressive Myoclonic Epilepsy Nervous System Diseases
C0751778 BXGD010587 Myoclonic Epilepsies, Progressive Nervous System Diseases
C0751779 BXGD010588 Action Myoclonus-Renal Failure Syndrome Nervous System Diseases
C0751780 BXGD010589 Biotin-Responsive Encephalopathy Nervous System Diseases
C0751781 BXGD010590 Dentatorubral-Pallidoluysian Atrophy Nervous System Diseases
C0751782 BXGD010591 May-White Syndrome Nervous System Diseases
C0751785 BXGD010594 Unverricht-Lundborg Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C1263846 BXGD011897 Attention deficit hyperactivity disorder Mental Disorders
C1305855 BXGD012348 Body mass index
C1836003 BXGD014069 Facial diplegia Infections; Nervous System Diseases; Stomatognathic Diseases
C1836150 BXGD014082 Gait imbalance
C1836830 BXGD014165 Developmental regression Mental Disorders
C1848207 BXGD014916 Poor speech Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C1866934 BXGD016427 Reduced tendon reflexes Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C3714756 BXGD019429 Intellectual Disability Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C3805911 BXGD019493 Increased cup-to-disc ratio
C3887485 BXGD019877 MIGRAINE WITH OR WITHOUT AURA, SUSCEPTIBILITY TO, 1
C4015420 BXGD020205 EPILEPSY, PROGRESSIVE MYOCLONIC 7 Nervous System Diseases
C4021759 BXGD020762 Generalized myoclonic seizures Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C4280747 BXGD022397 Choking episodes
C4477055 BXGD022912 Limb myoclonus Pathological Conditions, Signs and Symptoms; Nervous System Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0001842 Bergapten 216.19
BXGC0047867 Dalfampridine 94.05
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein