Showing entry for Fatty acid synthase


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT010694
Protein NameFatty acid synthase
Uniport IdP49327
GeneFASN
Gene Id2194
DomainAcyl_transf_1; ADH_zinc_N; KAsynt_C_assoc; ketoacyl-synt; Ketoacyl-synt_C; KR; Methyltransf_12; PP-binding; PS-DH; Thioesterase
Pfam PF00698   PF00107   PF16197   PF00109   PF02801   PF08659   PF08242   PF00550   PF14765   PF00975  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.3 Lipid metabolism hsa00061 Fatty acid biosynthesis
1. Metabolism 1.0 Global and overview maps hsa01100 Metabolic pathways
1. Metabolism 1.0 Global and overview maps hsa01212 Fatty acid metabolism
3. Environmental Information Processing 3.2 Signal transduction hsa04152 AMPK signaling pathway
5. Organismal Systems 5.2 Endocrine system hsa04910 Insulin signaling pathway
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006084 acetyl-CoA metabolic process
Biological Process GO:0071353 cellular response to interleukin-4
Biological Process GO:0006633 fatty acid biosynthetic process
Biological Process GO:0006631 fatty acid metabolic process
Biological Process GO:0046949 fatty-acyl-CoA biosynthetic process
Biological Process GO:0030879 mammary gland development
Biological Process GO:0001649 osteoblast differentiation
Biological Process GO:0031325 positive regulation of cellular metabolic process
Biological Process GO:0045540 regulation of cholesterol biosynthetic process
molecular function GO:0045296 cadherin binding
molecular function GO:0008144 drug binding
molecular function GO:0042802 identical protein binding
molecular function GO:0070402 NADPH binding
molecular function GO:0031177 phosphopantetheine binding
molecular function GO:0003723 RNA binding
cellular component GO:0005829 cytosol
cellular component GO:0070062 extracellular exosome
cellular component GO:0042587 glycogen granule
cellular component GO:0005794 Golgi apparatus
cellular component GO:0042470 melanosome
cellular component GO:0016020 membrane
cellular component GO:0005886 plasma membrane
molecular function GO:0008659 (3R)-hydroxymyristoyl-acyl-carrier-protein dehydratase activity
molecular function GO:0004313 acyl-carrier-protein S-acetyltransferase activity
molecular function GO:0004314 acyl-carrier-protein S-malonyltransferase activity
molecular function GO:0008693 3-hydroxydecanoyl-acyl-carrier-protein dehydratase activity
molecular function GO:0047451 3-hydroxyoctanoyl-acyl-carrier-protein dehydratase activity
molecular function GO:0004317 3-hydroxypalmitoyl-acyl-carrier-protein dehydratase activity
molecular function GO:0004316 3-oxoacyl-acyl-carrier-protein reductase (NADPH) activity
molecular function GO:0004315 3-oxoacyl-acyl-carrier-protein synthase activity
molecular function GO:0102131 3-oxo-glutaryl-acp methyl ester reductase activity
molecular function GO:0102132 3-oxo-pimeloyl-acp methyl ester reductase activity
molecular function GO:0047117 enoyl-acyl-carrier-protein reductase (NADPH, A-specific) activity
molecular function GO:0016295 myristoyl-acyl-carrier-protein hydrolase activity
molecular function GO:0004320 oleoyl-acyl-carrier-protein hydrolase activity
molecular function GO:0016296 palmitoyl-acyl-carrier-protein hydrolase activity
Reactome
Pathway Id Pathway Name
R-HSA-1430728 Metabolism
R-HSA-1430728 Metabolism
R-HSA-162582 Signal Transduction
R-HSA-163685 Integration of energy metabolism
R-HSA-163765 ChREBP activates metabolic gene expression
R-HSA-1655829 Regulation of cholesterol biosynthesis by SREBP (SREBF)
R-HSA-196849 Metabolism of water-soluble vitamins and cofactors
R-HSA-196854 Metabolism of vitamins and cofactors
R-HSA-199220 Vitamin B5 (pantothenate) metabolism
R-HSA-2426168 Activation of gene expression by SREBF (SREBP)
R-HSA-556833 Metabolism of lipids
R-HSA-556833 Metabolism of lipids
R-HSA-75105 Fatty acyl-CoA biosynthesis
R-HSA-75105 Fatty acyl-CoA biosynthesis
R-HSA-8957322 Metabolism of steroids
R-HSA-8978868 Fatty acid metabolism
R-HSA-8978868 Fatty acid metabolism
R-HSA-9006931 Signaling by Nuclear Receptors
R-HSA-9024446 NR1H2 and NR1H3-mediated signaling
R-HSA-9029558 NR1H2 & NR1H3 regulate gene expression linked to lipogenesis
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001418 BXGD000050 Adenocarcinoma Neoplasms
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0003123 BXGD000178 Anorexia Pathological Conditions, Signs and Symptoms
C0003130 BXGD000183 Anoxia Pathological Conditions, Signs and Symptoms
C0004763 BXGD000289 Barrett Esophagus Digestive System Diseases; Neoplasms
C0005684 BXGD000319 Malignant neoplasm of urinary bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0005695 BXGD000323 Bladder Neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0005967 BXGD000357 Bone neoplasms Neoplasms; Musculoskeletal Diseases
C0006118 BXGD000372 Brain Neoplasms Neoplasms; Nervous System Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006625 BXGD000401 Cachexia Pathological Conditions, Signs and Symptoms
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007097 BXGD000424 Carcinoma Neoplasms
C0007102 BXGD000425 Malignant tumor of colon Digestive System Diseases; Neoplasms
C0007103 BXGD000426 Malignant neoplasm of endometrium Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0007112 BXGD000429 Adenocarcinoma of prostate Neoplasms; Male Urogenital Diseases
C0007124 BXGD000437 Noninfiltrating Intraductal Carcinoma Neoplasms
C0007131 BXGD000441 Non-Small Cell Lung Carcinoma Neoplasms; Respiratory Tract Diseases
C0007137 BXGD000445 Squamous cell carcinoma Neoplasms
C0007138 BXGD000446 Carcinoma, Transitional Cell Neoplasms
C0007193 BXGD000451 Cardiomyopathy, Dilated Cardiovascular Diseases
C0007194 BXGD000452 Hypertrophic Cardiomyopathy Cardiovascular Diseases
C0008055 BXGD000514 Chikungunya Fever Infections
C0009081 BXGD000581 Congenital clubfoot Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0009324 BXGD000597 Ulcerative Colitis Digestive System Diseases
C0009375 BXGD000602 Colonic Neoplasms Digestive System Diseases; Neoplasms
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0010481 BXGD000673 Cushing Syndrome Endocrine System Diseases
C0010701 BXGD000688 Phyllodes Tumor Neoplasms
C0011175 BXGD000701 Dehydration Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0011311 BXGD000714 Dengue Fever Infections
C0011847 BXGD000749 Diabetes Endocrine System Diseases
C0011849 BXGD000751 Diabetes Mellitus Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011854 BXGD000753 Diabetes Mellitus, Insulin-Dependent Nutritional and Metabolic Diseases; Immune System Diseases; Endocrine System Diseases
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011881 BXGD000760 Diabetic Nephropathy Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0013274 BXGD000809 Patent ductus arteriosus Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0014070 BXGD000887 Encephalomyelitis Infections; Nervous System Diseases
C0014859 BXGD000961 Esophageal Neoplasms Digestive System Diseases; Neoplasms
C0015695 BXGD001013 Fatty Liver Digestive System Diseases
C0017636 BXGD001131 Glioblastoma Neoplasms
C0017638 BXGD001132 Glioma Neoplasms
C0018801 BXGD001226 Heart failure Cardiovascular Diseases
C0018802 BXGD001227 Congestive heart failure Cardiovascular Diseases
C0019163 BXGD001295 Hepatitis B Digestive System Diseases; Infections
C0019193 BXGD001299 Hepatitis, Toxic Digestive System Diseases; Chemically-Induced Disorders
C0019196 BXGD001301 Hepatitis C Digestive System Diseases; Infections
C0019348 BXGD001325 Herpes Simplex Infections Infections; Skin and Connective Tissue Diseases
C0020443 BXGD001385 Hypercholesterolemia Nutritional and Metabolic Diseases
C0020456 BXGD001392 Hyperglycemia Nutritional and Metabolic Diseases
C0020459 BXGD001394 Hyperinsulinism Nutritional and Metabolic Diseases
C0020473 BXGD001396 Hyperlipidemia Nutritional and Metabolic Diseases
C0020538 BXGD001422 Hypertensive disease Cardiovascular Diseases
C0020676 BXGD001462 Hypothyroidism Endocrine System Diseases
C0020796 BXGD001468 Profound Mental Retardation Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0021051 BXGD001475 Immunologic Deficiency Syndromes Immune System Diseases
C0021390 BXGD001503 Inflammatory Bowel Diseases Digestive System Diseases
C0022661 BXGD001572 Kidney Failure, Chronic Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0023212 BXGD001616 Left-Sided Heart Failure Cardiovascular Diseases
C0023269 BXGD001627 leiomyosarcoma Neoplasms
C0023418 BXGD001642 leukemia Neoplasms
C0023434 BXGD001643 Chronic Lymphocytic Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023530 BXGD001683 Leukopenia Hemic and Lymphatic Diseases
C0023827 BXGD001707 liposarcoma Neoplasms
C0023903 BXGD001720 Liver neoplasms Digestive System Diseases; Neoplasms
C0024121 BXGD001735 Lung Neoplasms Neoplasms; Respiratory Tract Diseases
C0024232 BXGD001751 Lymphatic Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0024623 BXGD001791 Malignant neoplasm of stomach Digestive System Diseases; Neoplasms
C0024814 BXGD001809 Marinesco-Sjogren syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0025202 BXGD001832 melanoma Neoplasms
C0025205 BXGD001833 Melanoma, Experimental Neoplasms
C0025286 BXGD001850 Meningioma Neoplasms; Nervous System Diseases
C0025363 BXGD001867 Mental Retardation, Psychosocial Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0025517 BXGD001875 Metabolic Diseases Nutritional and Metabolic Diseases
C0026277 BXGD001899 Mixed Salivary Gland Tumor Neoplasms
C0026764 BXGD001928 Multiple Myeloma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C0027533 BXGD001995 Neck Neoplasms Neoplasms
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0027794 BXGD002036 Neural Tube Defects Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0027832 BXGD002048 Neurofibromatosis 2 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Nervous System Diseases; Otorhinolaryngologic Diseases
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0029408 BXGD002137 Degenerative polyarthritis Musculoskeletal Diseases
C0029453 BXGD002154 Osteopenia Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0029456 BXGD002157 Osteoporosis Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0029463 BXGD002160 Osteosarcoma Neoplasms
C0029925 BXGD002181 Ovarian Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0030567 BXGD002240 Parkinson Disease Nervous System Diseases
C0032927 BXGD002381 Precancerous Conditions Neoplasms
C0033578 BXGD002408 Prostatic Neoplasms Neoplasms; Male Urogenital Diseases
C0034069 BXGD002458 Pulmonary Fibrosis Respiratory Tract Diseases
C0035334 BXGD002539 Retinitis Pigmentosa Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C0035335 BXGD002540 Retinoblastoma Neoplasms; Eye Diseases
C0036690 BXGD002632 Septicemia Pathological Conditions, Signs and Symptoms; Infections
C0038443 BXGD002757 Stress, Psychological Behavior and Behavior Mechanisms
C0041296 BXGD002903 Tuberculosis Infections
C0042133 BXGD002960 Uterine Fibroids Neoplasms
C0042341 BXGD002975 Varicocele Male Urogenital Diseases; Cardiovascular Diseases
C0042769 BXGD002999 Virus Diseases Infections
C0079744 BXGD003090 Diffuse Large B-Cell Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0085167 BXGD003137 Granular cell tumor Neoplasms
C0085207 BXGD003140 Gestational Diabetes Nutritional and Metabolic Diseases; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0086132 BXGD003264 Depressive Symptoms Behavior and Behavior Mechanisms
C0086692 BXGD003306 Benign Neoplasm Neoplasms
C0151718 BXGD003464 Hypocholesterolemia Nutritional and Metabolic Diseases
C0151779 BXGD003473 Cutaneous Melanoma Neoplasms; Skin and Connective Tissue Diseases
C0152013 BXGD003516 Adenocarcinoma of lung (disorder) Neoplasms
C0152018 BXGD003518 Esophageal carcinoma Digestive System Diseases; Neoplasms
C0153676 BXGD003679 Secondary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0153690 BXGD003684 Secondary malignant neoplasm of bone Pathological Conditions, Signs and Symptoms; Neoplasms; Musculoskeletal Diseases
C0162770 BXGD003980 Right Ventricular Hypertrophy Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0178664 BXGD004032 Glomerulosclerosis (disorder) Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Cardiovascular Diseases
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0205824 BXGD004128 Liposarcoma, Dedifferentiated Neoplasms
C0205825 BXGD004129 Liposarcoma, Pleomorphic Neoplasms
C0220630 BXGD004302 Adult Liver Carcinoma Digestive System Diseases; Neoplasms
C0220650 BXGD004310 Metastatic malignant neoplasm to brain Pathological Conditions, Signs and Symptoms; Neoplasms; Nervous System Diseases
C0220756 BXGD004338 Niemann-Pick Disease, Type C Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases; Hemic and Lymphatic Diseases
C0221271 BXGD004431 Elastosis perforans serpiginosa Skin and Connective Tissue Diseases
C0235527 BXGD004753 Heart Failure, Right-Sided Cardiovascular Diseases
C0235974 BXGD004796 Pancreatic carcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0236734 BXGD004823 Caffeine related disorders
C0238198 BXGD004893 Gastrointestinal Stromal Tumors Digestive System Diseases; Neoplasms
C0238463 BXGD004938 Papillary thyroid carcinoma Neoplasms; Endocrine System Diseases
C0242339 BXGD005150 Dyslipidemias Nutritional and Metabolic Diseases
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0243026 BXGD005210 Sepsis Pathological Conditions, Signs and Symptoms; Infections
C0278488 BXGD006515 Carcinoma breast stage IV
C0278608 BXGD006549 Adult Liposarcoma Neoplasms
C0278701 BXGD006566 Gastric Adenocarcinoma Digestive System Diseases; Neoplasms
C0278877 BXGD006608 Adult Meningioma Neoplasms; Nervous System Diseases
C0278883 BXGD006614 Metastatic melanoma Neoplasms
C0279000 BXGD006622 Liver and Intrahepatic Biliary Tract Carcinoma Digestive System Diseases; Neoplasms
C0279626 BXGD006657 Squamous cell carcinoma of esophagus Digestive System Diseases; Neoplasms
C0279628 BXGD006659 Adenocarcinoma Of Esophagus Digestive System Diseases; Neoplasms
C0279984 BXGD006703 Childhood Liposarcoma Neoplasms
C0280100 BXGD006713 Solid Neoplasm Neoplasms
C0281784 BXGD006785 Benign Meningioma Neoplasms; Nervous System Diseases
C0282612 BXGD006820 Prostatic Intraepithelial Neoplasias Neoplasms
C0334590 BXGD007129 Anaplastic Oligodendroglioma Neoplasms
C0334634 BXGD007144 Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0342443 BXGD007481 Adrenal Cushing's syndrome Endocrine System Diseases
C0344460 BXGD007674 Carcinoma ex pleomorphic adenoma Neoplasms; Stomatognathic Diseases
C0345904 BXGD007745 Malignant neoplasm of liver Digestive System Diseases; Neoplasms
C0346647 BXGD007832 Malignant neoplasm of pancreas Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0349530 BXGD007916 Early gastric cancer Digestive System Diseases; Neoplasms
C0349788 BXGD007956 Arrhythmogenic Right Ventricular Dysplasia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0374997 BXGD007967 Helicobacter pylori (H. pylori) infection in conditions classified elsewhere and of unspecified site
C0375023 BXGD007970 Respiratory syncytial virus (RSV) infection in conditions classified elsewhere and of unspecified site
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0400966 BXGD008266 Non-alcoholic Fatty Liver Disease Digestive System Diseases
C0424295 BXGD008524 Hyperactive behavior Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0431406 BXGD008686 Asymmetric crying face association Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Stomatognathic Diseases
C0456909 BXGD008883 Blindness Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C0476089 BXGD008977 Endometrial Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0494165 BXGD009022 Secondary malignant neoplasm of liver Digestive System Diseases; Neoplasms
C0496836 BXGD009042 Malignant tumor of eye Neoplasms; Eye Diseases
C0546837 BXGD009343 Malignant neoplasm of esophagus Digestive System Diseases; Neoplasms
C0585442 BXGD009593 Osteosarcoma of bone Neoplasms
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0686619 BXGD009835 Secondary malignant neoplasm of lymph node Pathological Conditions, Signs and Symptoms; Neoplasms
C0699790 BXGD009866 Colon Carcinoma Digestive System Diseases; Neoplasms
C0699791 BXGD009867 Stomach Carcinoma Digestive System Diseases; Neoplasms
C0699885 BXGD009869 Carcinoma of bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0740457 BXGD010000 Malignant neoplasm of kidney Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0742343 BXGD010061 Acute Chest Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Respiratory Tract Diseases; Hemic and Lymphatic Diseases
C0750927 BXGD010254 Apraxia, Developmental Verbal Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
C0853879 BXGD010982 Invasive carcinoma of breast Neoplasms; Skin and Connective Tissue Diseases
C0856169 BXGD011096 Endothelial dysfunction
C0860207 BXGD011220 Drug-Induced Liver Disease Digestive System Diseases; Chemically-Induced Disorders
C0917816 BXGD011419 Mental deficiency Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0919267 BXGD011426 ovarian neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0948089 BXGD011504 Acute Coronary Syndrome Cardiovascular Diseases
C1140680 BXGD011718 Malignant neoplasm of ovary Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1153706 BXGD011769 Endometrial adenocarcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C1168327 BXGD011787 High-Grade Prostatic Intraepithelial Neoplasia Neoplasms; Male Urogenital Diseases
C1257931 BXGD011815 Mammary Neoplasms, Human Neoplasms; Skin and Connective Tissue Diseases
C1262760 BXGD011886 Hepatitis, Drug-Induced Digestive System Diseases; Chemically-Induced Disorders
C1269955 BXGD012005 Tumor Cell Invasion
C1301034 BXGD012282 Pancreatic intraepithelial neoplasia Neoplasms
C1302401 BXGD012303 Adenoma of large intestine Digestive System Diseases; Neoplasms
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C1332201 BXGD012502 Adult Diffuse Large B-Cell Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1332986 BXGD012574 Childhood Osteosarcoma Neoplasms
C1335302 BXGD012775 Pancreatic Ductal Adenocarcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C1368683 BXGD012900 Epithelioma Neoplasms
C1370889 BXGD012920 Liposarcoma, well differentiated Neoplasms
C1378703 BXGD012933 Renal carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1449563 BXGD013086 Cardiomyopathy, Familial Idiopathic Cardiovascular Diseases
C1458155 BXGD013136 Mammary Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C1512127 BXGD013185 HER2 gene amplification
C1512409 BXGD013188 Hepatocarcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C1519680 BXGD013244 Tumor Immunity Pathological Conditions, Signs and Symptoms
C1608408 BXGD013434 Malignant transformation
C1621958 BXGD013468 Glioblastoma Multiforme Neoplasms
C1658953 BXGD013486 tumor vasculature
C1762616 BXGD013753 Meningioma, benign, no ICD-O subtype Neoplasms; Nervous System Diseases
C1832661 BXGD013866 ANOPHTHALMIA AND PULMONARY HYPOPLASIA Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Respiratory Tract Diseases
C1853698 BXGD015351 Rippling muscle disease Musculoskeletal Diseases; Nervous System Diseases
C1866119 BXGD016373 Autoimmune Lymphoproliferative Syndrome, Type IA Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Immune System Diseases; Hemic and Lymphatic Diseases
C1868684 BXGD016527 EAR, PATELLA, SHORT STATURE SYNDROME Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Stomatognathic Diseases; Otorhinolaryngologic Diseases
C1959583 BXGD016637 Myocardial Failure Cardiovascular Diseases
C1960398 BXGD016658 HER2-positive carcinoma of breast Neoplasms; Skin and Connective Tissue Diseases
C1961112 BXGD016674 Heart Decompensation Cardiovascular Diseases
C2004493 BXGD016875 Leukemia, B-Cell Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C2145472 BXGD016931 Urothelial Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2363741 BXGD017100 HIV-1 infection
C2711227 BXGD017478 Steatohepatitis Digestive System Diseases
C2931689 BXGD018049 Dystrophia myotonica 2 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C2931822 BXGD018068 Nasopharyngeal carcinoma Neoplasms; Stomatognathic Diseases; Otorhinolaryngologic Diseases
C2938924 BXGD018167 Oestrogen receptor positive breast cancer
C2939419 BXGD018178 Secondary Neoplasm Pathological Conditions, Signs and Symptoms; Neoplasms
C2986665 BXGD018237 Early-Stage Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C3241937 BXGD018578 Nonalcoholic Steatohepatitis Digestive System Diseases
C3495917 BXGD019012 Advanced breast cancer
C3539878 BXGD019087 Triple Negative Breast Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C3642345 BXGD019244 Luminal A Breast Carcinoma
C3658290 BXGD019256 Drug-Induced Acute Liver Injury Digestive System Diseases; Chemically-Induced Disorders
C3665419 BXGD019285 intracranial glioma Neoplasms; Nervous System Diseases
C3714514 BXGD019409 Infection Infections
C3714756 BXGD019429 Intellectual Disability Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C3887964 BXGD019934 POLYCYSTIC KIDNEY DISEASE 3 WITH OR WITHOUT POLYCYSTIC LIVER DISEASE
C3899403 BXGD020082 Decreased Concentration
C4022459 BXGD020900 Decreased adipose tissue
C4087504 BXGD022156 Peritoneal dissemination
C4277682 BXGD022376 Chemical and Drug Induced Liver Injury Digestive System Diseases; Chemically-Induced Disorders
C4279912 BXGD022378 Chemically-Induced Liver Toxicity Digestive System Diseases; Chemically-Induced Disorders
C4282128 BXGD022420 PATENT DUCTUS ARTERIOSUS 1 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C4524257 BXGD023102 MSI-low
C4529962 BXGD023178 Fatty Liver Disease
C4551472 BXGD023303 Hypertrophic obstructive cardiomyopathy Cardiovascular Diseases
C4688007 BXGD023582 Platinum-Resistant Ovarian Carcinoma
C4704874 BXGD023682 Mammary Carcinoma, Human Neoplasms; Skin and Connective Tissue Diseases
C4721208 BXGD023733 Metastatic castration-resistant prostate cancer
C4721209 BXGD023734 Metastatic human epidermal growth factor 2 positive carcinoma of breast Neoplasms; Skin and Connective Tissue Diseases
C4721414 BXGD023738 Mantle cell lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C4721610 BXGD023760 Carcinoma, Ovarian Epithelial Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C4722085 BXGD023788 Malignant neoplasm of colon and/or rectum
C4722518 BXGD023806 Triple-Negative Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C4733095 BXGD023910 HER2-negative breast cancer
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000298 Gentisein 244.2
BXGC0000436 Glycerol 92.09
BXGC0001807 1,5-Dihydroxy-3-methoxy-2-prenylxanthone 326.34
BXGC0001873 Epicatechin 290.27
BXGC0002588 Magnesium 24.31
BXGC0002591 Potassium 39.1
BXGC0002690 alpha-Catechin 290.27
BXGC0003705 Chloride 35.45
BXGC0004378 3-Hydroxyflavone 238.24
BXGC0004459 9-Hydroxycalabaxanthone 408.44
BXGC0005319 Garcinone E 464.55
BXGC0006223 Egonol 326.34
BXGC0006275 L-Methionine 149.21
BXGC0006635 Luteolin 286.24
BXGC0007559 gamma-Mangostin 396.43
BXGC0007560 alpha-Mangostin 410.46
BXGC0008149 beta-Mangostin 424.49
BXGC0013379 3,4,5,3'-Tetrahydroxybenzophenone 246.05
BXGC0013601 2,4,6,3',5'-Pentahydroxybenzophenone 262.05
BXGC0017352 Methylthioadenosine 297.09
BXGC0017572 n.a 432.18
BXGC0019395 n.a 418.16
BXGC0025529 Norathyriol 260.03
BXGC0026001 S-Methyl-L-methionine 164.07
BXGC0026935 Triclosan 287.95
BXGC0030485 Methylene-Bis-Methylphlorobutyrophenone 432.18
BXGC0033310 Epigalocatechin Gallate 458.08
BXGC0033892 n.a 446.19
BXGC0037187 flavaspidic acid-PB 432.18
BXGC0038881 n.a 626.24
BXGC0040454 flavaspidic acid-AB 418.16
BXGC0045748 n.a 418.16
BXGC0045749 n.a 432.18
BXGC0045750 n.a 404.15
BXGC0045751 n.a 460.21
BXGC0047405 Gamolenic Acid 278.22
BXGC0051733 Aspidinol-B 224.1
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein