Showing entry for Protein farnesyltransferase subunit beta



                       
General Target Information
BXGT IdBXGT010700
Protein NameProtein farnesyltransferase subunit beta
Uniport IdP49356
GeneFNTB
Gene Id100529261;2342
DomainPrenyltrans
Pfam PF00432  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.9 Metabolism of terpenoids and polyketides hsa00900 Terpenoid backbone biosynthesis
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0018343 protein farnesylation
Biological Process GO:0018342 protein prenylation
Biological Process GO:0022400 regulation of rhodopsin mediated signaling pathway
molecular function GO:0004660 protein farnesyltransferase activity
molecular function GO:0008270 zinc ion binding
cellular component GO:0005829 cytosol
cellular component GO:0005875 microtubule associated complex
cellular component GO:0005965 protein farnesyltransferase complex
Reactome
Pathway Id Pathway Name
R-HSA-1280215 Cytokine Signaling in Immune system
R-HSA-162582 Signal Transduction
R-HSA-168256 Immune System
R-HSA-2187338 Visual phototransduction
R-HSA-2514856 The phototransduction cascade
R-HSA-2514859 Inactivation, recovery and regulation of the phototransduction cascade
R-HSA-372790 Signaling by GPCR
R-HSA-388396 GPCR downstream signalling
R-HSA-418594 G alpha (i) signalling events
R-HSA-5673001 RAF/MAP kinase cascade
R-HSA-5683057 MAPK family signaling cascades
R-HSA-5684996 MAPK1/MAPK3 signaling
R-HSA-9607240 FLT3 Signaling
R-HSA-9648002 RAS processing
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0005890 BXGD000345 Body Height
C0014772 BXGD000948 Red Blood Cell Count measurement
C0023508 BXGD001675 White Blood Cell Count procedure
C0026769 BXGD001930 Multiple Sclerosis Immune System Diseases; Nervous System Diseases
C0200665 BXGD004045 Platelet mean volume determination (procedure)
C0524587 BXGD009232 Mean Corpuscular Volume (result)
C1261502 BXGD011856 Finding of Mean Corpuscular Hemoglobin
C1318315 BXGD012393 Serum zinc measurement
C4528257 BXGD023159 Corpuscular Hemoglobin Concentration Mean
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002675 Sugars 342.3
BXGC0004277 Acetic acid 60.05
BXGC0015355 Lauric anhydride 382.34
BXGC0024941 Itaconic anhydride 112.02
BXGC0045257 Lonafarnib 636.05
BXGC0049447 acetate 59.01
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein