Showing entry for Elongation factor Tu, mitochondrial


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT010703
Protein NameElongation factor Tu, mitochondrial
Uniport IdP49411
GeneTUFM
Gene Id7284
DomainGTP_EFTU; GTP_EFTU_D2; GTP_EFTU_D3
Pfam PF00009   PF03144   PF03143  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0070125 mitochondrial translational elongation
Biological Process GO:0045471 response to ethanol
Biological Process GO:0006414 translational elongation
Biological Process GO:0016032 viral process
molecular function GO:0003924 GTPase activity
molecular function GO:0005525 GTP binding
molecular function GO:0003723 RNA binding
molecular function GO:0003746 translation elongation factor activity
cellular component GO:0070062 extracellular exosome
cellular component GO:0016020 membrane
cellular component GO:0042645 mitochondrial nucleoid
cellular component GO:0005739 mitochondrion
Reactome
Pathway Id Pathway Name
R-HSA-392499 Metabolism of proteins
R-HSA-5368287 Mitochondrial translation
R-HSA-5389840 Mitochondrial translation elongation
R-HSA-72766 Translation
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001125 BXGD000024 Acidosis, Lactic Nutritional and Metabolic Diseases
C0003850 BXGD000225 Arteriosclerosis Cardiovascular Diseases
C0004096 BXGD000252 Asthma Respiratory Tract Diseases; Immune System Diseases
C0004153 BXGD000260 Atherosclerosis Cardiovascular Diseases
C0005893 BXGD000346 Body mass index procedure
C0007134 BXGD000443 Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0007193 BXGD000451 Cardiomyopathy, Dilated Cardiovascular Diseases
C0009324 BXGD000597 Ulcerative Colitis Digestive System Diseases
C0014772 BXGD000948 Red Blood Cell Count measurement
C0014859 BXGD000961 Esophageal Neoplasms Digestive System Diseases; Neoplasms
C0015934 BXGD001026 Fetal Growth Retardation Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications
C0017654 BXGD001136 Glomerular Filtration Rate
C0019163 BXGD001295 Hepatitis B Digestive System Diseases; Infections
C0019209 BXGD001305 Hepatomegaly Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0021390 BXGD001503 Inflammatory Bowel Diseases Digestive System Diseases
C0023434 BXGD001643 Chronic Lymphocytic Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023520 BXGD001678 Leukodystrophy Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C0024117 BXGD001734 Chronic Obstructive Airway Disease Respiratory Tract Diseases
C0024198 BXGD001743 Lyme Disease Infections
C0025958 BXGD001882 Microcephaly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C0028738 BXGD002081 Nystagmus Eye Diseases; Nervous System Diseases
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0030567 BXGD002240 Parkinson Disease Nervous System Diseases
C0040954 BXGD002890 Infection by Trichuris trichiura Infections
C0085584 BXGD003195 Encephalopathies Nervous System Diseases
C0151818 BXGD003480 Opisthotonus Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases
C0220981 BXGD004348 Metabolic acidosis Nutritional and Metabolic Diseases
C0220994 BXGD004357 Hyperammonemia Pathological Conditions, Signs and Symptoms
C0264802 BXGD005430 Dilated cardiomyopathy secondary to metabolic disorder Nutritional and Metabolic Diseases; Cardiovascular Diseases
C0266464 BXGD005676 Polymicrogyria Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0270612 BXGD006081 Leukoencephalopathy Nervous System Diseases
C0279702 BXGD006685 Conventional (Clear Cell) Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0518026 BXGD009069 body fat percentage (physical finding)
C0546837 BXGD009343 Malignant neoplasm of esophagus Digestive System Diseases; Neoplasms
C0578022 BXGD009541 Finding of body mass index
C1145670 BXGD011764 Respiratory Failure Respiratory Tract Diseases
C1836440 BXGD014115 Increased serum lactate Nutritional and Metabolic Diseases
C1836830 BXGD014165 Developmental regression Mental Disorders
C1857682 BXGD015736 Combined Oxidative Phosphorylation Deficiency 4 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C1858430 BXGD015792 Death in infancy
C1868683 BXGD016526 B-CELL MALIGNANCY, LOW-GRADE
C1963184 BXGD016688 Nystagmus, CTCAE 3.0
C2267233 BXGD017017 Neonatal Hypotonia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C3532239 BXGD019055 Mitochondrial cardiomyopathy
C4554036 BXGD023557 Nystagmus, CTCAE 5.0
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002682 Zinc 65.41
BXGC0042376 Picropodophyllotoxin 414.13
BXGC0047692 Gefitinib 446.15
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein