Showing entry for Cysteine--tRNA ligase, cytoplasmic


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT010714
Protein NameCysteine--tRNA ligase, cytoplasmic
Uniport IdP49589
GeneCARS1
Gene Id833
DomaintRNA-synt_1e
Pfam PF01406  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
2. Genetic Information Processing 2.2 Translation hsa00970 Aminoacyl-tRNA biosynthesis
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006423 cysteinyl-tRNA aminoacylation
Biological Process GO:0006418 tRNA aminoacylation for protein translation
molecular function GO:0005524 ATP binding
molecular function GO:0004817 cysteine-tRNA ligase activity
molecular function GO:0042802 identical protein binding
molecular function GO:0046872 metal ion binding
molecular function GO:0042803 protein homodimerization activity
molecular function GO:0000049 tRNA binding
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
Reactome
Pathway Id Pathway Name
R-HSA-379716 Cytosolic tRNA aminoacylation
R-HSA-379724 tRNA Aminoacylation
R-HSA-392499 Metabolism of proteins
R-HSA-72766 Translation
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001973 BXGD000095 Alcoholic Intoxication, Chronic Chemically-Induced Disorders; Mental Disorders
C0004352 BXGD000269 Autistic Disorder Mental Disorders
C0004941 BXGD000296 Behavioral Symptoms Behavior and Behavior Mechanisms
C0005890 BXGD000345 Body Height
C0011847 BXGD000749 Diabetes Endocrine System Diseases
C0011849 BXGD000751 Diabetes Mellitus Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011881 BXGD000760 Diabetic Nephropathy Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0022658 BXGD001570 Kidney Diseases Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0023980 BXGD001725 Longevity
C0025958 BXGD001882 Microcephaly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C0036690 BXGD002632 Septicemia Pathological Conditions, Signs and Symptoms; Infections
C0038454 BXGD002760 Cerebrovascular accident Nervous System Diseases; Cardiovascular Diseases
C0201925 BXGD004058 Calcium measurement
C0205710 BXGD004112 Alpers Syndrome (disorder) Immune System Diseases; Nervous System Diseases
C0206180 BXGD004170 Ki-1+ Anaplastic Large Cell Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0242966 BXGD005201 Systemic Inflammatory Response Syndrome Pathological Conditions, Signs and Symptoms
C0243026 BXGD005210 Sepsis Pathological Conditions, Signs and Symptoms; Infections
C0263490 BXGD005314 Brittle hair
C0270972 BXGD006147 Cornelia De Lange Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0333873 BXGD006971 Squamous intraepithelial lesion Pathological Conditions, Signs and Symptoms; Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0334121 BXGD006996 Inflammatory Myofibroblastic Tumor Pathological Conditions, Signs and Symptoms
C0424295 BXGD008524 Hyperactive behavior Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0428302 BXGD008625 Calcium level result
C0856975 BXGD011127 Autistic behavior Behavior and Behavior Mechanisms
C1510586 BXGD013176 Autism Spectrum Disorders Mental Disorders
C1856963 BXGD015662 Fragile nails Pathological Conditions, Signs and Symptoms
C3266262 BXGD018600 Multiple Chronic Conditions Pathological Conditions, Signs and Symptoms
C4022738 BXGD020974 Neurodevelopmental delay
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0006271 L-Cysteine 121.16
BXGC0042376 Picropodophyllotoxin 414.13
BXGC0047692 Gefitinib 446.15
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein