Showing entry for Estrogen receptor


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT010755
Protein NameEstrogen receptor
Uniport IdP49885
GeneESR1
Gene Id
DomainOest_recep; zf-C4
Pfam PF02159   PF00105  
OrganismOvis aries (Sheep)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0071392 cellular response to estradiol stimulus
Biological Process GO:0030518 intracellular steroid hormone receptor signaling pathway
Biological Process GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling
Biological Process GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway
Biological Process GO:0007204 positive regulation of cytosolic calcium ion concentration
Biological Process GO:0051091 positive regulation of DNA-binding transcription factor activity
Biological Process GO:0045429 positive regulation of nitric oxide biosynthetic process
Biological Process GO:0051000 positive regulation of nitric-oxide synthase activity
Biological Process GO:0010863 positive regulation of phospholipase C activity
Biological Process GO:0045893 positive regulation of transcription, DNA-templated
molecular function GO:0003700 DNA-binding transcription factor activity
molecular function GO:0030284 estrogen receptor activity
molecular function GO:0043565 sequence-specific DNA binding
molecular function GO:0005496 steroid binding
molecular function GO:0008270 zinc ion binding
cellular component GO:0005794 Golgi apparatus
cellular component GO:0005634 nucleus
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000130 Estradiol 272.38
BXGC0001899 Daidzein 254.24
BXGC0002071 Apigenin 270.24
BXGC0002627 17alpha-ethynylestradiol 296.4
BXGC0003707 Estrogen 268.36
BXGC0003773 Estriol 288.38
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein