Showing entry for Synaptotagmin-4


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT010783
Protein NameSynaptotagmin-4
Uniport IdP50232
GeneSyt4
Gene Id64440
DomainC2
Pfam PF00168  
OrganismRattus norvegicus (Rat)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007420 brain development
Biological Process GO:0017156 calcium-ion regulated exocytosis
Biological Process GO:0071277 cellular response to calcium ion
Biological Process GO:0099519 dense core granule cytoskeletal transport
Biological Process GO:0007613 memory
Biological Process GO:0045955 negative regulation of calcium ion-dependent exocytosis
Biological Process GO:0033604 negative regulation of catecholamine secretion
Biological Process GO:1905414 negative regulation of dense core granule exocytosis
Biological Process GO:0046929 negative regulation of neurotransmitter secretion
Biological Process GO:0050709 negative regulation of protein secretion
Biological Process GO:1905433 negative regulation of retrograde trans-synaptic signaling by neuropeptide
Biological Process GO:0048174 negative regulation of short-term neuronal synaptic plasticity
Biological Process GO:2000301 negative regulation of synaptic vesicle exocytosis
Biological Process GO:0031339 negative regulation of vesicle fusion
Biological Process GO:0007269 neurotransmitter secretion
Biological Process GO:1903861 positive regulation of dendrite extension
Biological Process GO:1905415 positive regulation of dense core granule exocytosis
Biological Process GO:0014049 positive regulation of glutamate secretion
Biological Process GO:0017158 regulation of calcium ion-dependent exocytosis
Biological Process GO:0014059 regulation of dopamine secretion
Biological Process GO:0030100 regulation of endocytosis
Biological Process GO:0099161 regulation of presynaptic dense core granule exocytosis
Biological Process GO:0031338 regulation of vesicle fusion
Biological Process GO:0061792 secretory granule maturation
Biological Process GO:0099183 trans-synaptic signaling by BDNF, modulating synaptic transmission
Biological Process GO:0006906 vesicle fusion
Biological Process GO:0061782 vesicle fusion with vesicle
Biological Process GO:0016192 vesicle-mediated transport
molecular function GO:0005544 calcium-dependent phospholipid binding
molecular function GO:0005509 calcium ion binding
molecular function GO:0030276 clathrin binding
molecular function GO:0001786 phosphatidylserine binding
molecular function GO:0046982 protein heterodimerization activity
molecular function GO:0042803 protein homodimerization activity
molecular function GO:0000149 SNARE binding
molecular function GO:0017075 syntaxin-1 binding
molecular function GO:0030348 syntaxin-3 binding
molecular function GO:0019905 syntaxin binding
cellular component GO:0097449 astrocyte projection
cellular component GO:0030424 axon
cellular component GO:0030425 dendrite
cellular component GO:0031045 dense core granule
cellular component GO:0070382 exocytic vesicle
cellular component GO:0098978 glutamatergic synapse
cellular component GO:0005794 Golgi apparatus
cellular component GO:0016021 integral component of membrane
cellular component GO:0099066 integral component of neuronal dense core vesicle membrane
cellular component GO:0098675 intrinsic component of neuronal dense core vesicle membrane
cellular component GO:1990742 microvesicle
cellular component GO:0043025 neuronal cell body
cellular component GO:0098992 neuronal dense core vesicle
cellular component GO:0043005 neuron projection
cellular component GO:0044306 neuron projection terminus
cellular component GO:0048471 perinuclear region of cytoplasm
cellular component GO:0005886 plasma membrane
cellular component GO:0030667 secretory granule membrane
cellular component GO:0036477 somatodendritic compartment
cellular component GO:0045202 synapse
cellular component GO:0008021 synaptic vesicle
cellular component GO:0031982 vesicle
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002586 Calcium 40.08
BXGC0003705 Chloride 35.45
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein