Showing entry for Corticosteroid 11-beta-dehydrogenase isozyme 2


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT010784
Protein NameCorticosteroid 11-beta-dehydrogenase isozyme 2
Uniport IdP50233
GeneHsd11b2
Gene Id25117
Domainadh_short
Pfam PF00106  
OrganismRattus norvegicus (Rat)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007565 female pregnancy
Biological Process GO:0008211 glucocorticoid metabolic process
Biological Process GO:0002017 regulation of blood volume by renal aldosterone
Biological Process GO:0042493 response to drug
Biological Process GO:0032094 response to food
Biological Process GO:0051384 response to glucocorticoid
Biological Process GO:0001666 response to hypoxia
Biological Process GO:0032868 response to insulin
Biological Process GO:0048545 response to steroid hormone
molecular function GO:0051287 NAD binding
molecular function GO:0005496 steroid binding
cellular component GO:0005737 cytoplasm
cellular component GO:0005783 endoplasmic reticulum
cellular component GO:0043231 intracellular membrane-bounded organelle
molecular function GO:0003845 11-beta-hydroxysteroid dehydrogenase NAD(P) activity
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0011627 Glycyrrhetic acid 470.69
BXGC0013582 Curcumin 368.13
BXGC0029810 1,5-Bis(4-Hydroxy-3-Methoxyphenyl)-1,4-Pentadien-3-One 326.12
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein