Showing entry for C-C chemokine receptor type 5


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT010879
Protein NameC-C chemokine receptor type 5
Uniport IdP51682
GeneCcr5
Gene Id12774
Domain7tm_1
Pfam PF00001  
OrganismMus musculus (Mouse)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006816 calcium ion transport
Biological Process GO:0019722 calcium-mediated signaling
Biological Process GO:0007267 cell-cell signaling
Biological Process GO:0060326 cell chemotaxis
Biological Process GO:0071222 cellular response to lipopolysaccharide
Biological Process GO:0006935 chemotaxis
Biological Process GO:0006952 defense response
Biological Process GO:0007186 G protein-coupled receptor signaling pathway
Biological Process GO:0006955 immune response
Biological Process GO:0006954 inflammatory response
Biological Process GO:0000165 MAPK cascade
Biological Process GO:0030517 negative regulation of axon extension
Biological Process GO:0030336 negative regulation of cell migration
Biological Process GO:2000110 negative regulation of macrophage apoptotic process
Biological Process GO:2000178 negative regulation of neural precursor cell proliferation
Biological Process GO:0070997 neuron death
Biological Process GO:0060139 positive regulation of apoptotic process by virus
Biological Process GO:0022409 positive regulation of cell-cell adhesion
Biological Process GO:0007204 positive regulation of cytosolic calcium ion concentration
Biological Process GO:0031622 positive regulation of fever generation
Biological Process GO:0010628 positive regulation of gene expression
Biological Process GO:0050729 positive regulation of inflammatory response
Biological Process GO:0032731 positive regulation of interleukin-1 beta production
Biological Process GO:0032755 positive regulation of interleukin-6 production
Biological Process GO:0045666 positive regulation of neuron differentiation
Biological Process GO:0032760 positive regulation of tumor necrosis factor production
Biological Process GO:0014808 release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
Biological Process GO:0070723 response to cholesterol
molecular function GO:0003779 actin binding
molecular function GO:0019957 C-C chemokine binding
molecular function GO:0016493 C-C chemokine receptor activity
molecular function GO:0071791 chemokine (C-C motif) ligand 5 binding
molecular function GO:0019956 chemokine binding
molecular function GO:0042802 identical protein binding
molecular function GO:0019901 protein kinase binding
cellular component GO:0009986 cell surface
cellular component GO:0005737 cytoplasm
cellular component GO:0005768 endosome
cellular component GO:0009897 external side of plasma membrane
cellular component GO:0016021 integral component of membrane
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0026391 Naloxone 327.15
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein