Showing entry for Methionine aminopeptidase 1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT010997
Protein NameMethionine aminopeptidase 1
Uniport IdP53582
GeneMETAP1
Gene Id23173
DomainPeptidase_M24; zf-C6H2
Pfam PF00557   PF15801  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0031365 N-terminal protein amino acid modification
Biological Process GO:0018206 peptidyl-methionine modification
Biological Process GO:0070527 platelet aggregation
Biological Process GO:0070084 protein initiator methionine removal
Biological Process GO:0022400 regulation of rhodopsin mediated signaling pathway
Biological Process GO:0006417 regulation of translation
molecular function GO:0004177 aminopeptidase activity
molecular function GO:0046872 metal ion binding
molecular function GO:0070006 metalloaminopeptidase activity
molecular function GO:0008235 metalloexopeptidase activity
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
Reactome
Pathway Id Pathway Name
R-HSA-162582 Signal Transduction
R-HSA-2187338 Visual phototransduction
R-HSA-2514856 The phototransduction cascade
R-HSA-2514859 Inactivation, recovery and regulation of the phototransduction cascade
R-HSA-372790 Signaling by GPCR
R-HSA-388396 GPCR downstream signalling
R-HSA-418594 G alpha (i) signalling events
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0027051 BXGD001963 Myocardial Infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0027651 BXGD002009 Neoplasms Neoplasms
C0041296 BXGD002903 Tuberculosis Infections
C0242723 BXGD005193 Parasitemia Pathological Conditions, Signs and Symptoms; Infections
C1269955 BXGD012005 Tumor Cell Invasion
C2930674 BXGD017891 Human Babesiosis Infections; Animal Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0002586 Calcium 40.08
BXGC0002591 Potassium 39.1
BXGC0003705 Chloride 35.45
BXGC0004277 Acetic acid 60.05
BXGC0006275 L-Methionine 149.21
BXGC0031354 Ovalicin 296.16
BXGC0042127 Oxyquinoline 145.05
BXGC0043968 Carbendazim 191.07
BXGC0044780 Cnicin 378.17
BXGC0049447 acetate 59.01
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein